Interferon gamma receptor 1 (IFNGR1) also known as CD119 (Cluster of Differentiation 119), is a protein that in humans is encoded by the IFNGR1 gene....
12 KB (1,390 words) - 22:37, 2 April 2024
The interferon-gamma receptor (IFNGR) protein complex is the heterodimer of two chains: IFNGR1 and IFNGR2. It binds interferon-γ, the sole member of interferon...
8 KB (870 words) - 23:14, 28 May 2024
heterodimeric receptor consisting of Interferon gamma receptor 1 (IFNGR1) and Interferon gamma receptor 2 (IFNGR2). IFN-γ binding to the receptor activates...
56 KB (6,476 words) - 06:27, 13 September 2024
biology, the interferon gamma receptor (IFNGR1) family is a family of proteins which includes several eukaryotic and viral interferon gamma receptor proteins...
3 KB (313 words) - 20:28, 22 December 2020
The interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. Endogenous human...
24 KB (2,617 words) - 19:43, 7 August 2022
Mendelian susceptibility to mycobacterial disease (redirect from Interferon gamma, receptor 1, deficiency)
complete deficiency in the interferon-gamma receptor have significant elevations in plasma concentrations of interferon-gamma, which can be measured by...
14 KB (1,413 words) - 03:44, 11 October 2023
Interferon gamma receptor 2 also known as IFN-γR2 is a protein which in humans is encoded by the IFNGR2 gene. This gene (IFNGR2) encodes the non-ligand-binding...
2 KB (245 words) - 00:15, 8 October 2023
interferon-alpha/beta receptor interferon-gamma receptor Interferon type III receptor Interleukin-10 receptor Interleukin-20 receptor Interleukin-22 receptor Interleukin-28...
6 KB (616 words) - 18:29, 7 June 2023
Based on the type of receptor through which they signal, human interferons have been classified into three major types. Interferon type I: All type I IFNs...
62 KB (7,065 words) - 05:17, 28 June 2024
Interleukin-28 receptor is a type II cytokine receptor found largely in epithelial cells. It binds type 3 interferons, interleukin-28 A (Interferon lambda 1), Interleukin-28B...
10 KB (1,126 words) - 20:57, 24 June 2021
proliferator-activated receptor gamma (PPAR-γ or PPARG), also known as the glitazone reverse insulin resistance receptor, or NR1C3 (nuclear receptor subfamily 1, group...
19 KB (2,091 words) - 05:22, 13 July 2024
Interferon alfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α), obtained from the...
7 KB (662 words) - 22:43, 14 September 2024
pseudogenes. Interferons bind to interferon receptors. All type I IFNs bind to a specific cell surface receptor complex known as the IFN-α receptor (IFNAR)...
24 KB (2,932 words) - 03:26, 14 June 2024
nigricans, type A Intercellular cholesterol esterification disease Interferon gamma, receptor 1, deficiency Internal carotid agenesis Intraocular lymphoma Interstitial...
7 KB (577 words) - 03:43, 30 March 2022
It interacts with the common gamma chain (γc) of type I cytokine receptors, to elicit signals from the IL-2 receptor family (e.g. IL-2R, IL-7R, IL-9R...
21 KB (2,423 words) - 20:04, 16 October 2024
lymphocytes. Immune interferon (IFN-gamma; MIM 147570) is produced by mitogen- or antigen-stimulated T lymphocytes.[supplied by OMIM] The interferons (IFN)s are...
24 KB (2,894 words) - 01:36, 26 August 2023
of interferon gamma (IFN-γ). It is a pro-inflammatory cytokine that shares similar biological effects to IL-12 and structural forms with the IL-1 family...
49 KB (6,005 words) - 13:33, 14 October 2024
Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian...
32 KB (2,851 words) - 23:22, 16 August 2024
Nishikawa H, et al. (February 2003). "Involvement of Toll-like receptor 4 signaling in interferon-gamma production and antitumor effect by streptococcal agent...
75 KB (9,082 words) - 22:17, 25 September 2024
Cell-mediated immunity (redirect from Type 1 immunity)
TH17 upon IL-1 or IL-23 exposure. Type 1 immunity makes use of the type 1 subset for each of these cell types. By secreting interferon gamma and TNF, TH1...
14 KB (1,381 words) - 19:57, 18 August 2024
Retinoic acid receptor gamma (RAR-γ), also known as NR1B3 (nuclear receptor subfamily 1, group B, member 3) is a nuclear receptor encoded by the RARG...
10 KB (1,208 words) - 06:34, 8 November 2023
problems. Interleukin 12 receptor, beta 1 deficiency IL-12p40 deficiency Interferon gamma receptor 1 deficiency Interferon gamma receptor 2 deficiency Tyk2 deficiency...
19 KB (1,836 words) - 09:52, 5 July 2024
Interleukin 10 (category Genes on human chromosome 1)
IL-22, IL-24 (Mda-7), IL-26 and interferons type-I (IFN-alpha, -beta, -epsilon, -kappa, -omega), type-II (IFN-gamma) and type-III (IFN-lambda, including...
40 KB (4,619 words) - 05:18, 22 August 2024
RIG-I (category RIG-I-like receptors)
gene I) is a cytosolic pattern recognition receptor (PRR) that can mediate induction of a type-I interferon (IFN1) response. RIG-I is an essential molecule...
23 KB (2,831 words) - 16:57, 27 August 2024
Interleukin 12 (redirect from IL-12 and IL-12 Receptor β1 Mutations)
the growth and function of T cells. It stimulates the production of interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) from T cells and natural...
14 KB (1,578 words) - 23:52, 11 October 2024
The common gamma chain (γc) (or CD132), also known as interleukin-2 receptor subunit gamma or IL-2RG, is a cytokine receptor sub-unit that is common to...
16 KB (2,092 words) - 14:33, 22 June 2024
IL-2Rβ, or CD122), and γ (gamma) (also called IL-2Rγ, γc, common gamma chain, or CD132); these subunits are also parts of receptors for other cytokines.: 713 ...
9 KB (934 words) - 16:50, 3 October 2024
Together with peroxisome proliferator-activated receptor delta and peroxisome proliferator-activated receptor gamma, PPAR-alpha is part of the subfamily of peroxisome...
22 KB (2,567 words) - 20:42, 4 October 2024
STAT1 (redirect from Signal transducer and activator of transcription 1)
Specifically STAT1 can be activated by several ligands such as Interferon alpha (IFNα), Interferon gamma (IFNγ), Epidermal Growth Factor (EGF), Platelet Derived...
31 KB (3,702 words) - 10:57, 15 July 2024
RAR-related orphan receptor gamma (RORγ) is a protein that in humans is encoded by the RORC (RAR-related orphan receptor C) gene. RORγ is a member of...
21 KB (2,372 words) - 01:41, 15 December 2023