Intracellular receptors are globular protein receptors located inside the cell rather than on its cell membrane. The word intracellular means "within...

diffuse passively across the plasma membrane and interact with intracellular receptors. Cell signaling can occur over short or long distances, and can...

protein-coupled receptors, and enzyme-linked hormone receptors. Intracellular receptors are those found inside the cell, and include cytoplasmic receptors and nuclear...

protoplasm and are referred to as intracellular or nuclear receptors, such as testosterone. Upon hormone binding, the receptor can initiate multiple signaling...

ganglion cells. Receptors can be roughly divided into two major classes: intracellular and extracellular receptors. Extracellular receptors are integral...

protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G...

Ryanodine receptors (RyR for short) form a class of intracellular calcium channels in various forms of excitable animal tissue like muscles and neurons...

metabotropic receptor is activated, a series of intracellular events are triggered that can also result in ion channels opening or other intracellular events...

cell(s). Recognition of the hormone by an associated cell membrane or intracellular receptor protein. Relay and amplification of the received hormonal signal...

hormone receptors are found in the nucleus, cytosol, and also on the plasma membrane of target cells. They are generally intracellular receptors (typically...

of the receptor kept intracellular. The majority of enzyme-linked receptors are, or associate with, protein kinases. G protein-coupled receptors are integral...

protein binds to the third intracellular loop of all opioid receptors. Both in mice and humans, the genes for the various receptor subtypes are located on...

of ERs. The first includes the intracellular estrogen receptors, namely ERα and ERβ, which belong to the nuclear receptor family. The second class consists...

domains being the receptor itself. The activated receptor as a result then becomes autophosphorylated on multiple specific intracellular tyrosine residues...

proliferator-activated receptor alpha (PPAR-α), also known as NR1C1 (nuclear receptor subfamily 1, group C, member 1), is a nuclear receptor protein functioning...

Intracellular parasites are microparasites that are capable of growing and reproducing inside the cells of a host. They are also called intracellular...

The vitamin D receptor (VDR also known as the calcitriol receptor) is a member of the nuclear receptor family of transcription factors. Calcitriol (the...

noradrenaline are receptor ligands to either α1, α2 or β-adrenoreceptors. The α1 couples to Gq, which results in increased intracellular Ca2+ and subsequent...

in the heart, and in the central nervous system. The H1 receptor is linked to an intracellular G-protein (Gq) that activates phospholipase C and the inositol...

TAAR1 gene. TAAR1 is a primarily intracellular amine-activated Gs-coupled and Gq-coupled G protein-coupled receptor (GPCR) that is primarily expressed...

scope and effect of ligand binding on σ1 receptors has led some to believe that σ1 receptors are intracellular signal transduction amplifiers. Recently...

domain-like receptors, or NOD-like receptors (NLRs) (also known as nucleotide-binding leucine-rich repeat receptors), are intracellular sensors of pathogen-associated...

to a monomeric receptor that has seven transmembrane regions; in this case, the ligand is ACh. This receptor is bound to intracellular proteins, known...

nuclear receptors are a class of proteins responsible for sensing steroids, thyroid hormones, vitamins, and certain other molecules. These intracellular receptors...

cell surface receptor. Sigma-2 is an EXPERA domain protein with a mostly intracellular (ER membrane) localization. Because the σ-receptor was originally...

encoded by the NR4A1 gene. Nuclear receptor 4A1 (NR4A1) is a member of the NR4A nuclear receptor family of intracellular transcription factors. NR4A1 is...

activity on the intracellular side. Hence a catalytic receptor is an integral membrane protein possessing both catalytic, and receptor functions. They...

the receptor is responsible for binding glucagon-like peptide-1 (GLP-1) ligands, while the intracellular C-terminus interacts with intracellular signaling...

responsible for subsequent intracellular signaling pathways. Upon cleavage of the monomer to its respective α- and β-chains, receptor hetero or homo-dimerisation...

receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca2+ ion channel found in neurons. The NMDA receptor is...