Krüppel-like Factor 2 (KLF2), also known as lung Krüppel-like Factor (LKLF), is a protein that in humans is encoded by the KLF2 gene on chromosome 19....

the upregulation of adult hemoglobin in adult definitive erythrocytes, and KLF2, which is vital to the expression of embryonic hemoglobin. Many CRMs have...

Additional genes, however, including certain members of the Klf family (Klf1, Klf2, Klf4, and Klf5), the Myc family (c-myc, L-myc, and N-myc), Nanog, and LIN28...

ENSG00000171872 C2H2 ZF Known motif – High-throughput in vitro [466] MMCCACVCWCCCMTY KLF2 ENSG00000127528 C2H2 ZF Known motif – High-throughput in vitro [467] VCCMCRCCCH...

HGNC:20717 Q6P597 8215 KLC4 HGNC:21624 Q9NSK0 8216 KLF1 HGNC:6345 Q13351 8217 KLF2 HGNC:6347 Q9Y5W3 8218 KLF3 HGNC:16516 P57682 8219 KLF4 HGNC:6348 O43474 8220...

morphology), with Klf2 being required for the mechanism to occur. It has been proposed that PRDM14 induces this state by activating Klf2 via active demethylation...

presence of an isochromosome 17, and, rarely, mutations in the NOTCH2 and KLF2 genes. Some of these genomic abnormalities are similar to those found in...

fingers at its carboxyl terminus that are closely related to another KLF, KLF2. It has two nuclear localization sequences that signals it to localize to...

[GBP5], dual-specificity phosphatase 3 [DUSP3], and Krüppel-like factor 2 [KLF2] genes to differentiate between active TB and other diseases. In 2007, a...

channel TRPV4, subsequently facilitating the Notch signaling pathway via KLF2 and activating various downstream effectors such as BMP-2 and HER2/neu. In...

Trebicka, Jonel; Schierwagen, Robert (2015-01-16). "Statins, Rho GTPases and KLF2: new mechanistic insight into liver fibrosis and portal hypertension". Gut...

q arm of chromosome 3 in 10-20% of cases. Mutations in genes such as: 1 KLF2 (21% of cases), a transcription factor that indirectly regulates the NF-κB...

PMC 3731817. PMID 24294107. "www.genecards.org/cgi-bin/carddisp.pl?gene=KLF2". www.genecards.org. Retrieved 2016-05-09. Ikeda K, Kawakami K (1995). "DNA...

thus resistance to DNA-damage induced apoptosis. Kruppel-like factor 2 (KLF2) negatively regulates human WEE1, thus increasing sensitivity to DNA-damage...

Hirschsprung's disease: Gene locus map 19p13.3 GTPBP3: GTP binding protein 3 19p13.11 KLF2: Krüppel-like factor 2, also known as Lung Krüppel-like factor. Gene map...

cells into the cortical plate. WWP1 has been shown to interact with: CPSF6, KLF2, and Reticulon 4 GRCh38: Ensembl release 89: ENSG00000123124 – Ensembl, May...

with value of 4 indicating the highest conservation and -0.5 the lowest. KLF2 and KLF5 had scores of 3.73 each. The species being compared were elephant...

complex with STAU1, UPF1, and KLF2 mRNA, which promotes SMD and KLF2 transcripts. Knockdown of STAU1 or overexpression of KLF2 in SGC7901 and BGC823 increased...

Sp/KLF family. The following human genes encode Kruppel-like factors: KLF1, KLF2, KLF3, KLF4, KLF5, KLF6, KLF7, KLF8, KLF9, KLF10, KLF11, KLF12, KLF13, KLF14...

regulatory factor X5 0.758 CEBPB CCAAT/enhancer-binding protein beta 0.959 KLF2 Kruppel-like factor 2 (LKLF) 0.986 CSRNP1 cysteine/serine-rich nuclear protein...

expression is inhibited by microRNA-92a and activated by transcription factor KLF2. In addition to LPA receptor-mediated signaling, PPAP2B is also associated...

receptor S1PR1, homing receptor to lymph node CD62L, activation marker KLRG1, KLF2 and CCR7 than TEM in the blood. Other TRM: The majority of TRM express CD69...

expressions. It was found that Kruppel-like family of transcription factors (KLF2, KLF12, and KLF15), which were anti-inflammatory regulators, were down-regulated...

and is strongly affected by other pluripotency factors such as Nanog and KLF2. HTATSF1 has been shown to interact with SUPT5H and GTF2F2. GRCh38: Ensembl...

in B lymphocytes is complex but it appears to operate in a network with KLF2 and KLF4 to influence the switch between spleen marginal zone and follicular...

co-localization with CTCF-independent pluripotency factors (Oct4, Nanog, Sox4, and KLF2). RAD21 cooperates with CTCF, tissue-specific transcription factors, and...