Cardiolipin (IUPAC name 1,3-bis(sn-3’-phosphatidyl)-sn-glycerol, "sn" designating stereospecific numbering) is an important component of the inner mitochondrial...

Anti-cardiolipin antibodies (ACA) are antibodies often directed against cardiolipin and found in several diseases, including syphilis, antiphospholipid...

with anti-mitochondrial antibodies have been identified. M1 – cardiolipin (Anti-cardiolipin antibodies, ACA) M2 – branched-chain alpha-keto acid dehydrogenase...

musculature and muscle weakness, growth delay, exercise intolerance, cardiolipin abnormalities, and 3-methylglutaconic aciduria. It can be associated...

to cardiolipin by reacting with a molecule of cytidine diphosphate diglyceride in a reaction catalyzed by cardiolipin synthase. Glycerol Cardiolipin Lipid-gated...

extract of ox heart (diphosphatidyl glycerol). It therefore detects anti-cardiolipin antibodies (IgG, IgM or IgA), visualized through foaming of the test...

phospholipid:diacylglycerol acyltransferases). It catalyzes remodeling of immature cardiolipin to its mature composition containing a predominance of tetralinoleoyl...

after an ischemia and prevent cardiolipin from being catabolized by phospholipase A2. It can also work to restore cardiolipin levels in the inner mitochondrial...

mitochondrial ROS production is stimulated, and cardiolipin is oxidized by a peroxidase function of the cardiolipin–cytochrome c complex. The hemoprotein is...

reduce the production of toxic reactive oxygen species and stabilize cardiolipin. Stealth Peptides, a privately held company, was founded in 2006 to develop...

against substances released by cells when they are damaged by T. pallidum (cardiolipin and lecithin). Traditionally, syphilis serologic testing has been performed...

MTP did indeed have cardiolipin remodeling capabilities. This suggests a possible link between mitochondrial membrane cardiolipin content and beta oxidation...

detect lupus anticoagulant, anti-apolipoprotein antibodies, and/or anti-cardiolipin antibodies. Antiphospholipid syndrome can be primary or secondary. •...

biosynthesis of cardiolipin in mitochondria, and its overexpression in cultured cells resulted in increased cardiolipin synthase activity. As cardiolipin is synthesized...

that cardiolipin is a likely player in mitochondrial apoptosis. In a study done by R Lee et al., it was found that during apoptosis, cardiolipin in the...

monolysocardiolipin (MLCL) into cardiolipin. In 1990, biologists Michael Schlame and Bernd Rustow observed the deacylation of cardiolipin into MLCL, which was then...

homodimer. This is required for activity. Dimers are connected by a cardiolipin molecule, which has been found to play a key role in stabilization of...

phospholipid composition. Phosphatidylcholine makes up about 26.5%, cardiolipin 25.4%, and phosphatidylinositol 4.5%. In S. cerevisiae mitochondria,...

the APOH gene. One of its functions is to bind cardiolipin. When bound, the structure of cardiolipin and β2-GP1 both undergo large changes in structure...

particular requires the presence of cardiolipin, a unique mitochondrial lipid. In yeast mitochondria lacking cardiolipin, the number of enzymes forming respiratory...

Additionally, the inner membrane is rich in an unusual phospholipid, cardiolipin. This phospholipid was originally discovered in cow hearts in 1942, and...

erythematosus but often detected in people without the disease), anti-cardiolipin antibodies, and anti-β2-glycoprotein 1 antibodies; it is therefore regarded...

mitochondria and chloroplasts, and also bacterial cell membranes; and that cardiolipin is found only in the inner mitochondrial membrane and bacterial cell...

generally tested in conjunction with anti-apolipoprotein antibodies and anti-cardiolipin antibodies, and diagnostic criteria require one clinical event (i.e....

anticoagulant-positive". Another autoantibody finding in SLE is the anti-cardiolipin antibody, which can cause a false positive test for syphilis.[citation...

Sodium oxide (NaO) Nonyl Acridine Orange, a fluorescent die. It can stain cardiolipin content of mitochondria. North Atlantic oscillation, a climatic phenomenon...

acid-induced apoptosis in MDA-MB-231 breast cancer cells. A role for cardiolipin". The Journal of Biological Chemistry. 278 (34): 31861–31870. doi:10...

ATP synthases, but the FO subcomplex has many unique subunits. It uses cardiolipin. The inhibitory IF1 also binds differently, in a way shared with trypanosomatida...

of proteins that acts as a mitochondrial phosphatase in cardiolipin biosynthesis. Cardiolipin is a unique dimeric phosphoglycerolipid predominantly present...

blood or cerebrospinal fluid is taken and introduced to the antigen – cardiolipin extracted from bovine muscle or heart. Syphilis non-specific antibodies...