Killer-cell immunoglobulin-like receptors (KIRs), are a family of type I transmembrane glycoproteins expressed on the plasma membrane of natural killer...
35 KB (4,222 words) - 22:14, 16 June 2024
Killer cell immunoglobulin-like receptor 2DL3 is a transmembrane glycoprotein expressed by the natural killer cells and the subsets of the T cells. The...
8 KB (1,031 words) - 02:09, 1 December 2023
NK cells possess two types of surface receptors: activating receptors and inhibitory receptors, including killer-cell immunoglobulin-like receptors. Most...
74 KB (9,180 words) - 04:00, 11 March 2024
possess a domain known as an immunoglobulin domain or fold. Members of the IgSF include cell surface antigen receptors, co-receptors and co-stimulatory molecules...
16 KB (847 words) - 10:57, 24 June 2024
The leukocyte immunoglobulin-like receptors (LILR) are a family of receptors possessing extracellular immunoglobulin domains. They are also known as CD85...
3 KB (340 words) - 03:30, 3 January 2023
Fc receptor is a protein found on the surface of certain cells – including, among others, B lymphocytes, follicular dendritic cells, natural killer cells...
42 KB (4,735 words) - 03:31, 26 March 2024
for the Killer-cell immunoglobulin-like receptors (KIRs) and for the Killer Inhibitory Receptors. The Killer-cell immunoglobulin-like receptors involve...
20 KB (2,287 words) - 12:23, 15 May 2024
UPR. Cell surface B27 heavy chains and dimers can bind to regulatory immune receptors such as members of the killer cell immunoglobulin-like receptor family...
16 KB (1,516 words) - 09:54, 16 February 2024
KIR2DL1 (category Immunoglobulin superfamily)
Killer cell immunoglobulin-like receptor 2DL1 is a protein that in humans is encoded by the KIR2DL1 gene. Killer-cell immunoglobulin-like receptors (KIRs)...
11 KB (1,372 words) - 06:23, 1 January 2024
Antibody (redirect from Receptors, antigen, b-cell)
form of a B cell receptor; the term immunoglobulin (Ig) can refer to either the membrane-bound form or the secreted form of the B cell receptor, but they...
118 KB (13,262 words) - 09:47, 22 June 2024
Immune system (redirect from Cell-mediated immune reactions)
2005, p. 17. Rajalingam 2012, Chapter: Overview of the killer cell immunoglobulin-like receptor system. Kawai T, Akira S (February 2006). "Innate immune...
118 KB (13,493 words) - 15:10, 22 June 2024
Interleukin-10 receptor subunit alpha precursor - Homo sapiens (Human)". www.uniprot.org. Retrieved 2015-10-13. "IL10RB - Interleukin-10 receptor subunit beta...
96 KB (467 words) - 06:58, 14 October 2022
believed. B cells, unlike the other two classes of lymphocytes, T cells and natural killer cells, express B cell receptors (BCRs) on their cell membrane...
32 KB (3,752 words) - 22:20, 13 July 2024
A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a...
31 KB (3,843 words) - 08:24, 16 June 2024
CD56, as CD56dim cNK cells are more likely to express killer-cell immunoglobulin-like receptors (KIRs) and/or CD94/NKG2C. These surface molecules are required...
12 KB (1,311 words) - 21:25, 1 September 2023
toll-like receptor (TLR) family. TLR9 is an important receptor expressed in immune system cells including dendritic cells, macrophages, natural killer cells...
20 KB (2,551 words) - 21:43, 4 April 2024
chimeric antigen receptors (CARs)—also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors—are receptor proteins that...
82 KB (8,595 words) - 09:48, 28 June 2024
Ly49 (category Cell biology)
receptors is found in the human genome, KLRA1P (LY49L), however, it represents a non-functional pseudogene. However killer cell immunoglobulin-like receptors...
8 KB (952 words) - 22:54, 16 September 2023
Immune checkpoint (redirect from T-cell checkpoints)
short for Killer-cell Immunoglobulin-like Receptor, is a receptor for MHC Class I molecules on Natural Killer cells. Bristol-Myers Squibb is working on...
31 KB (3,467 words) - 01:27, 25 June 2024
KIR2DL4 (category Immunoglobulin superfamily)
Killer cell immunoglobulin-like receptor 2DL4 is a protein that in humans is encoded by the KIR2DL4 gene. Killer cell immunoglobulin-like receptors (KIRs)...
9 KB (1,225 words) - 00:37, 8 November 2023
receptors called toll-like receptors (TLRs) that are expressed on the membranes of leukocytes including dendritic cells, macrophages, natural killer cells...
60 KB (6,685 words) - 08:19, 24 June 2024
Killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 is a protein that in humans is encoded by the KIR2DS1 gene. Killer cell...
6 KB (705 words) - 13:59, 29 November 2023
KIR2DS4 (category Immunoglobulin superfamily)
Killer cell immunoglobulin-like receptor 2DS4 is a protein that in humans is encoded by the KIR2DS4 gene. Killer cell immunoglobulin-like receptors (KIRs)...
8 KB (1,071 words) - 21:42, 9 March 2024
channel Kir Killer-cell immunoglobulin-like receptor, a receptor protein expressed on the surface of natural killer cells and some T-cells Kir (river)...
1 KB (180 words) - 01:45, 23 December 2021
Lymphocyte (redirect from Lymphoid Cell)
innate lymphoid cells (ILCs; "innate T cell-like" cells involved in mucosal immunity and homeostasis), of which natural killer cells are an important...
23 KB (2,443 words) - 05:18, 25 June 2024
in receptor desensitization, in modulating membrane structure events, in regulating transcription, in mediating immune responses, in regulating cell growth...
27 KB (2,650 words) - 21:16, 19 March 2024
KIR3DL3 (category Immunoglobulin superfamily)
Killer cell immunoglobulin-like receptor 3DL3 is a protein that in humans is encoded by the KIR3DL3 gene. Killer cell immunoglobulin-like receptors (KIRs)...
9 KB (1,105 words) - 23:05, 3 February 2024
Antibody-dependent cellular cytotoxicity (redirect from Antibody-dependent cell-mediated cytotoxicity)
other cell. ADCC requires an effector cell which classically is known to be natural killer (NK) cells that typically interact with immunoglobulin G (IgG)...
13 KB (1,661 words) - 22:18, 9 December 2023
neoplastic cells in DLBCL, NOS exhibit pathologically overactive NF-κB, PI3K/AKT/mTOR, JAK-STAT0, MAPK/ERK, B-cell receptor, toll-like receptor, and NF-κB...
69 KB (8,143 words) - 18:36, 22 January 2024
Alloimmunity (section NK cells)
and on their ligands expressed by the graft. Receptors of KIR (Killer-cell immunoglobulin-like receptor) family bind concrete MHC class I molecules. If...
18 KB (2,381 words) - 22:48, 14 September 2022