• Killer-cell immunoglobulin-like receptors (KIRs), are a family of type I transmembrane glycoproteins expressed on the plasma membrane of natural killer...
    35 KB (4,222 words) - 22:14, 16 June 2024
  • Thumbnail for Killer cell immunoglobulin-like receptor 2DL3
    Killer cell immunoglobulin-like receptor 2DL3 is a transmembrane glycoprotein expressed by the natural killer cells and the subsets of the T cells. The...
    8 KB (1,031 words) - 02:09, 1 December 2023
  • Thumbnail for Natural killer cell
    NK cells possess two types of surface receptors: activating receptors and inhibitory receptors, including killer-cell immunoglobulin-like receptors. Most...
    74 KB (9,180 words) - 04:00, 11 March 2024
  • Thumbnail for Immunoglobulin superfamily
    possess a domain known as an immunoglobulin domain or fold. Members of the IgSF include cell surface antigen receptors, co-receptors and co-stimulatory molecules...
    16 KB (847 words) - 10:57, 24 June 2024
  • The leukocyte immunoglobulin-like receptors (LILR) are a family of receptors possessing extracellular immunoglobulin domains. They are also known as CD85...
    3 KB (340 words) - 03:30, 3 January 2023
  • Thumbnail for Fc receptor
    Fc receptor is a protein found on the surface of certain cells – including, among others, B lymphocytes, follicular dendritic cells, natural killer cells...
    42 KB (4,735 words) - 03:31, 26 March 2024
  • Thumbnail for Killer activation receptor
    for the Killer-cell immunoglobulin-like receptors (KIRs) and for the Killer Inhibitory Receptors. The Killer-cell immunoglobulin-like receptors involve...
    20 KB (2,287 words) - 12:23, 15 May 2024
  • Thumbnail for HLA-B27
    UPR. Cell surface B27 heavy chains and dimers can bind to regulatory immune receptors such as members of the killer cell immunoglobulin-like receptor family...
    16 KB (1,516 words) - 09:54, 16 February 2024
  • Thumbnail for KIR2DL1
    KIR2DL1 (category Immunoglobulin superfamily)
    Killer cell immunoglobulin-like receptor 2DL1 is a protein that in humans is encoded by the KIR2DL1 gene. Killer-cell immunoglobulin-like receptors (KIRs)...
    11 KB (1,372 words) - 06:23, 1 January 2024
  • Thumbnail for Antibody
    form of a B cell receptor; the term immunoglobulin (Ig) can refer to either the membrane-bound form or the secreted form of the B cell receptor, but they...
    118 KB (13,262 words) - 09:47, 22 June 2024
  • Thumbnail for Immune system
    2005, p. 17. Rajalingam 2012, Chapter: Overview of the killer cell immunoglobulin-like receptor system. Kawai T, Akira S (February 2006). "Innate immune...
    118 KB (13,493 words) - 15:10, 22 June 2024
  • Interleukin-10 receptor subunit alpha precursor - Homo sapiens (Human)". www.uniprot.org. Retrieved 2015-10-13. "IL10RB - Interleukin-10 receptor subunit beta...
    96 KB (467 words) - 06:58, 14 October 2022
  • Thumbnail for B cell
    believed. B cells, unlike the other two classes of lymphocytes, T cells and natural killer cells, express B cell receptors (BCRs) on their cell membrane...
    32 KB (3,752 words) - 22:20, 13 July 2024
  • Thumbnail for Cytotoxic T cell
    A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a...
    31 KB (3,843 words) - 08:24, 16 June 2024
  • Thumbnail for Adaptive NK cell
    CD56, as CD56dim cNK cells are more likely to express killer-cell immunoglobulin-like receptors (KIRs) and/or CD94/NKG2C. These surface molecules are required...
    12 KB (1,311 words) - 21:25, 1 September 2023
  • Thumbnail for Toll-like receptor 9
    toll-like receptor (TLR) family. TLR9 is an important receptor expressed in immune system cells including dendritic cells, macrophages, natural killer cells...
    20 KB (2,551 words) - 21:43, 4 April 2024
  • chimeric antigen receptors (CARs)—also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors—are receptor proteins that...
    82 KB (8,595 words) - 09:48, 28 June 2024
  • Ly49 (category Cell biology)
    receptors is found in the human genome, KLRA1P (LY49L), however, it represents a non-functional pseudogene. However killer cell immunoglobulin-like receptors...
    8 KB (952 words) - 22:54, 16 September 2023
  • Thumbnail for Immune checkpoint
    short for Killer-cell Immunoglobulin-like Receptor, is a receptor for MHC Class I molecules on Natural Killer cells. Bristol-Myers Squibb is working on...
    31 KB (3,467 words) - 01:27, 25 June 2024
  • Thumbnail for KIR2DL4
    KIR2DL4 (category Immunoglobulin superfamily)
    Killer cell immunoglobulin-like receptor 2DL4 is a protein that in humans is encoded by the KIR2DL4 gene. Killer cell immunoglobulin-like receptors (KIRs)...
    9 KB (1,225 words) - 00:37, 8 November 2023
  • Thumbnail for Toll-like receptor
    receptors called toll-like receptors (TLRs) that are expressed on the membranes of leukocytes including dendritic cells, macrophages, natural killer cells...
    60 KB (6,685 words) - 08:19, 24 June 2024
  • Killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 is a protein that in humans is encoded by the KIR2DS1 gene. Killer cell...
    6 KB (705 words) - 13:59, 29 November 2023
  • Thumbnail for KIR2DS4
    KIR2DS4 (category Immunoglobulin superfamily)
    Killer cell immunoglobulin-like receptor 2DS4 is a protein that in humans is encoded by the KIR2DS4 gene. Killer cell immunoglobulin-like receptors (KIRs)...
    8 KB (1,071 words) - 21:42, 9 March 2024
  • channel Kir Killer-cell immunoglobulin-like receptor, a receptor protein expressed on the surface of natural killer cells and some T-cells Kir (river)...
    1 KB (180 words) - 01:45, 23 December 2021
  • Thumbnail for Lymphocyte
    Lymphocyte (redirect from Lymphoid Cell)
    innate lymphoid cells (ILCs; "innate T cell-like" cells involved in mucosal immunity and homeostasis), of which natural killer cells are an important...
    23 KB (2,443 words) - 05:18, 25 June 2024
  • in receptor desensitization, in modulating membrane structure events, in regulating transcription, in mediating immune responses, in regulating cell growth...
    27 KB (2,650 words) - 21:16, 19 March 2024
  • Thumbnail for KIR3DL3
    KIR3DL3 (category Immunoglobulin superfamily)
    Killer cell immunoglobulin-like receptor 3DL3 is a protein that in humans is encoded by the KIR3DL3 gene. Killer cell immunoglobulin-like receptors (KIRs)...
    9 KB (1,105 words) - 23:05, 3 February 2024
  • Thumbnail for Antibody-dependent cellular cytotoxicity
    other cell. ADCC requires an effector cell which classically is known to be natural killer (NK) cells that typically interact with immunoglobulin G (IgG)...
    13 KB (1,661 words) - 22:18, 9 December 2023
  • Thumbnail for Diffuse large B-cell lymphoma
    neoplastic cells in DLBCL, NOS exhibit pathologically overactive NF-κB, PI3K/AKT/mTOR, JAK-STAT0, MAPK/ERK, B-cell receptor, toll-like receptor, and NF-κB...
    69 KB (8,143 words) - 18:36, 22 January 2024
  • and on their ligands expressed by the graft. Receptors of KIR (Killer-cell immunoglobulin-like receptor) family bind concrete MHC class I molecules. If...
    18 KB (2,381 words) - 22:48, 14 September 2022