Lenalidomide, sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic...
29 KB (2,483 words) - 05:43, 9 August 2024
83% at 30 months, lenalidomide plus low-dose dexamethasone an 82% survival at 2 years, and melphalan, prednisone, and lenalidomide had a 90% survival...
131 KB (13,509 words) - 07:49, 11 November 2024
There may be accompanying erythroid hypoplasia in the bone marrow. Lenalidomide has activity in 5q- syndrome and is FDA approved for red blood cell (RBC)...
7 KB (639 words) - 13:49, 23 September 2024
that makes cancer and immunology drugs. Its major product is Revlimid (lenalidomide), which is used in the treatment of multiple myeloma, and also in certain...
32 KB (2,807 words) - 21:37, 19 October 2024
blood cells, and antibiotics. Drug therapy may include the medications lenalidomide, antithymocyte globulin, and azacitidine. Some people can be cured by...
61 KB (6,719 words) - 14:44, 6 November 2024
imide group. The IMiD class includes thalidomide and its analogues (lenalidomide, pomalidomide, mezigdomide and iberdomide). These drugs may also be referred...
49 KB (5,487 words) - 11:41, 24 January 2024
humanized IgG1 monoclonal antibody medication used in combination with lenalidomide and dexamethasone, for adults that have received 1 to 3 prior therapies...
14 KB (1,196 words) - 14:55, 2 July 2024
including treatment with bortezomib and an immunomodulatory therapy (such as lenalidomide) and have demonstrated disease progression on or within 60 days of completion...
19 KB (1,730 words) - 05:43, 7 April 2024
under the brand name Monjuvi, is a medication used in combination with lenalidomide for the treatment of adults with relapsed or refractory diffuse large...
11 KB (677 words) - 19:53, 7 November 2024
months (in the placebo+lenalidomide+dexamethasone study arm including 362 people) to 20.6 months (under ixazomib+lenalidomide+dexamethasone, 360 people)...
17 KB (1,693 words) - 06:49, 1 July 2024
sponsored numerous clinical trials with analogues to thalidomide, such as lenalidomide, that are substantially more powerful and have fewer side effects — except...
76 KB (7,432 words) - 14:59, 21 November 2024
Lenalidomide or lenalidomide plus dexamethasone (Rd) is a common treatment for high risk SMM. Many clinical trials have shown that a lenalidomide based...
13 KB (1,570 words) - 13:38, 1 September 2024
(Thal-dex), lenalidomide, bortezomib (Velcade, Vel-dex), or a combination of doxorubicin (Adriamycin) and vincristine or bortezomib/lenalidomide/dexamethasone...
72 KB (6,433 words) - 04:45, 17 November 2024
for multiple myeloma show great promise in combination therapy with lenalidomide and dexamethasone, as well as with bortezomib and dexamethasone.[needs...
22 KB (1,836 words) - 05:53, 21 September 2024
2,6-piperidinedione. It is the core of a variety of drugs, including lenalidomide, a medication used to treat anemia and multiple myeloma; and cycloheximide...
2 KB (146 words) - 16:33, 5 August 2024
License Application (BLA) to the FDA for tafasitamab in combination with lenalidomide for the treatment of relapsed/refractory diffuse large B-cell lymphoma...
17 KB (1,435 words) - 09:34, 28 August 2024
cereblon E3 ligase modulator; it has a higher binding affinity than lenalidomide or pomalidomide. It is developed by Bristol Myers Squibb for various...
11 KB (746 words) - 15:52, 3 June 2024
myeloma who have received at least one prior treatment regimen including lenalidomide; and in combination with dexamethasone is indicated in the treatment...
18 KB (1,271 words) - 13:56, 16 October 2024
The drug lenalidomide contains substructures isoindoline (red) and glutarimide (blue)...
29 KB (3,241 words) - 16:15, 22 October 2024
The drug lenalidomide contains substructures isoindoline (red) and glutarimide (blue)...
27 KB (2,773 words) - 16:33, 26 October 2024
inotuzumab ozogamicin, or epratuzumab and immunomodulators such as lenalidomide and interferon. The latter medications have been used in combination...
67 KB (7,967 words) - 13:33, 14 October 2024
being studied. Immunomodulatory imide drugs such as thalidomide and lenalidomide have been used in combination with dexamethasone to treat POEMS syndrome...
24 KB (2,233 words) - 16:16, 21 September 2024
The inhibition potency of apremilast in TNF-α production is similar to lenalidomide. Celgene reported seven kinds of crystal forms — A, B, C, D, E, F, and...
23 KB (1,907 words) - 02:31, 17 October 2024
Zuclopenthixol Acitretin Adapalene Bexarotene Isotretinoin Tretinoin Thalidomide Lenalidomide Pomalidomide List revoked in September 2016. Abacavir Amprenavir Atazanavir...
26 KB (1,722 words) - 09:50, 2 November 2024
treatment for AL amyloidosis. Other drugs used to treat myeloma such as lenalidomide have shown promise in treating AL amyloidosis. Chemotherapy drugs are...
155 KB (17,518 words) - 23:36, 26 October 2024
treatment of multiple myelomas in adults. It was seen that bortezomib plus lenalidomide plus dexamethasone as well as bortezomib plus melphalan and prednisone...
24 KB (2,272 words) - 08:01, 11 November 2024
and some synthetic derivatives are commercially valuable drugs, e.g. lenalidomide and pazinaclone. 1-Substituted isoindolines and isoindolinones are chiral...
3 KB (275 words) - 16:19, 5 August 2024
unclear. A phase I clinical research trial found that the addition of lenalidomide to the R-CHOP regimen produce an ~80% complete response rate in GBC as...
69 KB (8,143 words) - 23:37, 9 November 2024
L04AX01 Azathioprine L04AX02 Thalidomide L04AX03 Methotrexate L04AX04 Lenalidomide L04AX05 Pirfenidone L04AX06 Pomalidomide L04AX07 Dimethyl fumarate L04AX08...
3 KB (367 words) - 15:37, 25 January 2024
(green tea) Cannabinoids (cannabis, Echinacea purpurea) Curcumin (turmeric) LA-SS-Az Lenalidomide LSD Pentoxifylline Pomalidomide R-DOI TCB-2 Thalidomide...
49 KB (6,227 words) - 14:52, 18 November 2024