• Macrophage-1 antigen (or integrin αMβ2 or macrophage integrin or Mac-1) is a complement receptor ("CR3") consisting of CD11b (integrin αM) and CD18 (integrin...
    9 KB (1,138 words) - 00:32, 9 November 2023
  • Thumbnail for Macrophage
    lymphocytes. For example, they are important as antigen presenters to T cells. In humans, dysfunctional macrophages cause severe diseases such as chronic granulomatous...
    92 KB (10,131 words) - 14:06, 1 July 2024
  • Function-associated Antigen 1, also called αLβ2 integrin Mac1 (CD11b/CD18) present on macrophages that is also called Macrophage-1 antigen (CR3) and αMβ2 integrin...
    1,012 bytes (87 words) - 01:41, 12 July 2023
  • Thumbnail for Antigen-presenting cell
    can present antigens in some way. They are found in a variety of tissue types. Dedicated antigen-presenting cells, including macrophages, B cells and...
    16 KB (2,128 words) - 09:55, 4 March 2024
  • CR3 or CR-3 may refer to: Macrophage-1 antigen, an immunological cell surface receptor for a complement component CR3, an x86 microprocessor control register...
    791 bytes (138 words) - 23:04, 26 September 2022
  • Thumbnail for Intercellular adhesion molecule
    members, designated ICAM-1 to ICAM-5. They are known to bind to leucocyte integrins CD11/CD18 such as LFA-1 and Macrophage-1 antigen, during inflammation...
    2 KB (156 words) - 10:59, 24 June 2024
  • Thumbnail for Alveolar macrophage
    evidenced by downregulated expression of the phagocytic receptor Macrophage 1 antigen (Mac-1). AMs actively suppress the induction of two of the immunity...
    33 KB (3,862 words) - 16:23, 12 June 2024
  • Thumbnail for Integrin alpha M
    heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM is also known as CR3A...
    15 KB (1,716 words) - 17:02, 7 November 2023
  • subtype. M2a macrophages are activated by IL-4 and IL-13 which evokes upregulated expression of arginase-1, mannose receptor MRc1 (CD206), antigen presentation...
    26 KB (3,077 words) - 07:06, 18 October 2023
  • receptors bind effector protein fragments that are produced in response to antigen-antibody complexes or damage-associated molecules. Complement receptor...
    6 KB (376 words) - 06:42, 5 March 2024
  • Thumbnail for Antigen
    cytotoxic T lymphocytes (CTL), antibody-secreting B cells, macrophages and other particles. Some antigens start out as exogenous and later become endogenous (for...
    20 KB (2,435 words) - 08:54, 4 March 2024
  • Thumbnail for Cell-mediated immunity
    encounter an antigen, are converted into activated effector T cells after encountering antigen-presenting cells (APCs). These APCs, such as macrophages, dendritic...
    14 KB (1,381 words) - 03:19, 4 May 2024
  • Mac1 (redirect from MAC-1)
    MAC-1 may refer to: Macrophage-1 antigen Integrin alpha M Macintosh This disambiguation page lists articles associated with the same title formed as a...
    138 bytes (49 words) - 17:27, 20 July 2020
  • Thumbnail for T helper cell
    T helper cell (redirect from Type 1 T-cell)
    surface of professional antigen-presenting cells (APCs). Professional antigen-presenting cells are primarily dendritic cells, macrophages and B cells, although...
    54 KB (6,597 words) - 01:56, 6 June 2024
  • Thumbnail for Integrin beta 2
    protein ICAM-1. Binding of CD18 and CD11b-d results in the formation of complement receptors (e.g. Macrophage-1 antigen receptor, Mac-1, when bound to...
    11 KB (1,299 words) - 10:15, 11 December 2023
  • and antigen presentation. BMDMs provide a large homogenous population of macrophages that play an increasingly important role in making macrophage-related...
    6 KB (719 words) - 02:43, 3 December 2023
  • Integrin alpha5beta1 Leukocyte-adhesion receptor: LFA-1 - Heterodimer: CD11a / CD18 Macrophage-1 antigen (CR3) - Heterodimer: CD11b / CD18 Integrin alphaXbeta2...
    38 KB (2,656 words) - 12:11, 30 October 2023
  • Thumbnail for Dermal macrophage
    macrophages belong to the mononuclear phagocyte system that serves a vital role in the innate immunity of the skin. They are also a type of antigen-presenting...
    20 KB (2,371 words) - 23:00, 5 January 2024
  • distinct functions: phagocytosis and antigen presentation. Phagocytosis is the main process of macrophages and antigen presentation the main property of...
    6 KB (601 words) - 19:35, 12 August 2023
  • Thumbnail for Mannose receptor C-type 1
    tuberculosis-infected human macrophages exhibit enhanced cellular adhesion with increased expression of LFA-1 and ICAM-1 and reduced expression and/or...
    5 KB (679 words) - 10:00, 18 August 2023
  • Thumbnail for CD74
    HLA class II histocompatibility antigen gamma chain also known as HLA-DR antigens-associated invariant chain or CD74 (Cluster of Differentiation 74),...
    19 KB (2,221 words) - 01:42, 3 December 2023
  • Thumbnail for Phagocyte
    oxidants and nitric oxide. After phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a phagocyte...
    74 KB (8,277 words) - 16:30, 29 May 2024
  • response by inhibiting neutrophils and macrophages from invading the infection site early on. One cause of antigenic escape is that a pathogen's epitopes...
    14 KB (1,583 words) - 13:38, 30 December 2023
  • Thumbnail for PD-L1
    PD-L1 (redirect from Cd274 antigens)
    oxide production by macrophages, reduced granzyme B production by NK cells, and decreased proliferation of L. monocytogenes antigen-specific CD8 T cells...
    25 KB (3,073 words) - 18:36, 5 July 2024
  • Thumbnail for CD68
    CD (September 1994). "Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1". Immunology. 83 (1): 140–7. PMC 1415006. PMID 7821959...
    12 KB (1,369 words) - 13:37, 10 May 2024
  • Thumbnail for Immune complex
    internalization and processing of antigen, maturation of the vesicles containing the internalized antigen, and activation in DCs and macrophages. There are multiple...
    11 KB (1,295 words) - 22:22, 1 July 2024
  • Thumbnail for MHC class II
    MHC class II (redirect from Hla-d antigens)
    molecules normally found only on professional antigen-presenting cells such as dendritic cells, macrophages, some endothelial cells, thymic epithelial cells...
    16 KB (2,022 words) - 21:07, 5 June 2024
  • Thumbnail for Duffy antigen system
    Duffy antigen/chemokine receptor (DARC), also known as Fy glycoprotein (FY) or CD234 (Cluster of Differentiation 234), is a protein that in humans is...
    75 KB (9,574 words) - 18:04, 24 April 2024
  • Thumbnail for Murine respirovirus
    molecule -1 (ICAM-1, CD54), which is a glycoprotein that serves as a ligand for macrophage-1 antigen (Mac-1) and lymphocyte function-associated antigen 1 (LFA-1...
    295 KB (31,886 words) - 17:12, 23 June 2024
  • Tumor-associated macrophages (TAMs) are a class of immune cells present in high numbers in the microenvironment of solid tumors. They are heavily involved...
    21 KB (2,424 words) - 00:10, 3 January 2024