Macrophage-1 antigen (or integrin αMβ2 or macrophage integrin or Mac-1) is a complement receptor ("CR3") consisting of CD11b (integrin αM) and CD18 (integrin...

can present antigens in some way. They are found in a variety of tissue types. Dedicated antigen-presenting cells, including macrophages, B cells and...

Function-associated Antigen 1, also called αLβ2 integrin Mac1 (CD11b/CD18) present on macrophages that is also called Macrophage-1 antigen (CR3) and αMβ2 integrin...

lymphocytes. For example, they are important as antigen presenters to T cells. In humans, dysfunctional macrophages cause severe diseases such as chronic granulomatous...

CR3 or CR-3 may refer to: Macrophage-1 antigen, an immunological cell surface receptor for a complement component CR3, an x86 microprocessor control register...

members, designated ICAM-1 to ICAM-5. They are known to bind to leucocyte integrins CD11/CD18 such as LFA-1 and Macrophage-1 antigen, during inflammation...

evidenced by downregulated expression of the phagocytic receptor Macrophage 1 antigen (Mac-1). AMs actively suppress the induction of two of the immunity...

heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM is also known as CR3A...

receptors bind effector protein fragments that are produced in response to antigen-antibody complexes or damage-associated molecules. Complement receptor...

and antigen presentation. BMDMs provide a large homogenous population of macrophages that play an increasingly important role in making macrophage-related...

encounter an antigen, are converted into activated effector T cells after encountering antigen-presenting cells (APCs). These APCs, such as macrophages, dendritic...

surface of professional antigen-presenting cells (APCs). Professional antigen-presenting cells are primarily dendritic cells, macrophages and B cells, although...

cytotoxic T lymphocytes (CTL), antibody-secreting B cells, macrophages and other particles. Some antigens start out as exogenous and later become endogenous (for...

MAC-1 may refer to: Macrophage-1 antigen Integrin alpha M Macintosh This disambiguation page lists articles associated with the same title formed as a...

tuberculosis-infected human macrophages exhibit enhanced cellular adhesion with increased expression of LFA-1 and ICAM-1 and reduced expression and/or...

subtype. M2a macrophages are activated by IL-4 and IL-13 which evokes upregulated expression of arginase-1, mannose receptor MRc1 (CD206), antigen presentation...

macrophages belong to the mononuclear phagocyte system that serves a vital role in the innate immunity of the skin. They are also a type of antigen-presenting...

recommendation is level 1. THP-1 cells are used as a models to study the monocyte-macrophage differentiation process, antigen presentation and as a model...

HLA class II histocompatibility antigen gamma chain also known as HLA-DR antigens-associated invariant chain or CD74 (Cluster of Differentiation 74),...

protein ICAM-1. Binding of CD18 and CD11b-d results in the formation of complement receptors (e.g. Macrophage-1 antigen receptor, Mac-1, when bound to...

distinct functions: phagocytosis and antigen presentation. Phagocytosis is the main process of macrophages and antigen presentation the main property of...

oxidants and nitric oxide. After phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a phagocyte...

Integrin alpha5beta1 Leukocyte-adhesion receptor: LFA-1 - Heterodimer: CD11a / CD18 Macrophage-1 antigen (CR3) - Heterodimer: CD11b / CD18 Integrin alphaXbeta2...

of activating B lymphocytes. TI-1 antigen, which has an activity that can directly activate B cells and TI-2 antigen, which has highly repetitive structure...

response by inhibiting neutrophils and macrophages from invading the infection site early on. One cause of antigenic escape is that a pathogen's epitopes...

molecules normally found only on professional antigen-presenting cells such as dendritic cells, macrophages, some endothelial cells, thymic epithelial cells...

form bridges between their antigenic sites hindering their proper functioning. Their presence might also attract macrophages or killer cells to attack...

CD (September 1994). "Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1". Immunology. 83 (1): 140–7. PMC 1415006. PMID 7821959...

trial number NCT02215967 for "Study of T Cells Targeting B-Cell Maturation Antigen for Previously Treated Multiple Myeloma" at ClinicalTrials.gov "Celgene...

internalization and processing of antigen, maturation of the vesicles containing the internalized antigen, and activation in DCs and macrophages. There are multiple...