• The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide, referring to...
    7 KB (751 words) - 22:09, 29 July 2024
  • group, the C-terminus, and an end with an unbound amine group, the N-terminus. Proteins are naturally synthesized starting from the N-terminus and ending...
    6 KB (607 words) - 07:14, 3 September 2024
  • Thumbnail for XPG N terminus
    molecular biology the protein domain XPG refers to, in this case, the N-terminus of XPG. The XPG protein can be corrected by a 133 kDa nuclear protein...
    5 KB (559 words) - 03:21, 29 November 2023
  • Thumbnail for Protein
    as the N-terminus or amino terminus, whereas the end of the protein with a free carboxyl group is known as the C-terminus or carboxy terminus (the sequence...
    103 KB (11,472 words) - 16:37, 31 October 2024
  • Thumbnail for Post-translational modification
    O-acylation (esters), N-acylation (amides), S-acylation (thioesters) acetylation, the addition of an acetyl group, either at the N-terminus of the protein or...
    32 KB (3,131 words) - 03:19, 21 November 2024
  • Thumbnail for Protein primary structure
    in the opposite order (starting at the C-terminus) to biological protein synthesis (starting at the N-terminus). Protein sequence is typically notated...
    21 KB (2,599 words) - 01:04, 11 November 2024
  • bond to the C-terminus, but entropically it was more favorable to hydrogen bond with the N-terminus. Specifically, they found that C-terminus hydrogen bonding...
    22 KB (3,076 words) - 01:13, 10 August 2024
  • (usually 16-30 amino acids long) present at the N-terminus (or occasionally nonclassically at the C-terminus or internally) of most newly synthesized proteins...
    15 KB (1,749 words) - 23:12, 13 August 2024
  • Thumbnail for Protein sequencing
    Edman degradation remains a valuable tool for characterizing a protein's N-terminus. It is often desirable to know the unordered amino acid composition of...
    21 KB (2,836 words) - 10:57, 8 February 2024
  • myristoyl group at the N-terminus being able to covalently attach to the membranes. Other amino acid residues at the N-terminus are important for membrane...
    10 KB (1,215 words) - 14:38, 22 September 2024
  • Thumbnail for N,N'-Dicyclohexylcarbodiimide
    DMAP. In protein synthesis (such as Fmoc solid-state synthesizers), the N-terminus is often used as the attachment site on which the amino acid monomers...
    14 KB (1,191 words) - 13:39, 7 July 2024
  • Thumbnail for Arginylation
    fully intact proteins, not just on the N-terminus of protein fragments or pre-processed proteins. In 1986, the N-end rule was elucidated, and it states...
    21 KB (2,495 words) - 23:15, 20 February 2024
  • Thumbnail for Peptide synthesis
    starts at the carboxyl end of the peptide (C-terminus), and proceeds toward the amino-terminus (N-terminus). Protein biosynthesis (long peptides) in living...
    54 KB (6,128 words) - 03:44, 11 November 2024
  • Thumbnail for Ubiquitin
    threonine residues through an ester bond, or the amino group of the protein's N-terminus via a peptide bond. The protein modifications can be either a single ubiquitin...
    97 KB (11,029 words) - 03:48, 27 October 2024
  • Thumbnail for G protein-coupled receptor
    seven-transmembrane receptors. Ligands can bind either to the extracellular N-terminus and loops (e.g. glutamate receptors) or to the binding site within transmembrane...
    82 KB (9,384 words) - 16:34, 5 September 2024
  • Thumbnail for Angiotensin
    other proteins of the serpin family, but angiotensinogen has an elongated N-terminus compared to other serpin family proteins. Obtaining actual crystals for...
    29 KB (3,163 words) - 19:13, 18 October 2024
  • Thumbnail for Z-DNA
    to the E3L protein that determine virulence are the N-terminus and the C-terminus. The N-terminus is made of up a sequence similar to that of the Zα domain...
    34 KB (4,310 words) - 05:43, 18 September 2024
  • Western blotting. The peptide sequence of the FLAG-tag from the N-terminus to the C-terminus is: DYKDDDDK (1012 Da). Additionally, FLAG-tags may be used in...
    7 KB (846 words) - 22:41, 10 August 2024
  • Thumbnail for Integral membrane protein
    positioned such that their carboxyl-terminus is towards the cytosol, or Type II, which have their amino-terminus towards the cytosol. Type III proteins...
    9 KB (1,035 words) - 19:59, 25 January 2024
  • the N-terminus of dnaB whereas the other dnaB-dnaC complex will complex with dnaA from the dnaC. After the assembly of dnaG onto the N-terminus of dnaB...
    2 KB (231 words) - 12:19, 5 February 2024
  • Thumbnail for Directionality (molecular biology)
    a 5′-to-3′ direction, and will extend the protein from its N-terminus toward its C-terminus. For example, in a typical gene a start codon (5′-ATG-3′) is...
    9 KB (1,191 words) - 13:38, 29 May 2024
  • Thumbnail for Chhatrapati Shivaji Terminus
    Chhatrapati Shivaji Terminus (officially Chhatrapati Shivaji Maharaj Terminus since 2017, formerly Victoria Terminus (VT), Bombay station code: CSMT (mainline)/ST...
    24 KB (2,220 words) - 19:18, 20 November 2024
  • Thumbnail for Pertactin
    important components of acellular pertussis vaccine. A large part of the N-terminus of the pertactin protein is composed of beta helix repeats. This region...
    4 KB (433 words) - 17:16, 22 May 2024
  • Thumbnail for Wiskott–Aldrich syndrome protein
    autoinhibited conformation with sequences near its C-terminus binding to a region near its N-terminus. Its activation is dependent upon CDC42 and PIP2 acting...
    21 KB (2,588 words) - 00:21, 5 February 2024
  • the N-terminus glycosylations that occur post-translation and contribute to an increase in apparent size of the mature receptor. The amino terminus of...
    8 KB (963 words) - 00:05, 3 April 2024
  • Thumbnail for Alpha helix
    outside of the helix, and point roughly "downward" (i.e., toward the N-terminus), like the branches of an evergreen tree (Christmas tree effect). This...
    46 KB (5,219 words) - 12:42, 20 November 2024
  • Thumbnail for Teriparatide
    Forteo, is a form of parathyroid hormone (PTH) consisting of the first (N-terminus) 34 amino acids, which is the bioactive portion of the hormone. It is...
    27 KB (2,054 words) - 06:31, 7 July 2024
  • Thumbnail for Single-chain variable fragment
    or threonine for solubility, and can either connect the N-terminus of the VH with the C-terminus of the VL, or vice versa. This protein retains the specificity...
    11 KB (1,228 words) - 17:51, 29 July 2023
  • amino acid is released from the amino or the carboxy terminal (N-terminus or C-terminus), an exopeptidase is further classified as an aminopeptidase or...
    2 KB (241 words) - 15:41, 8 November 2024
  • mitochondrial matrix have specific signal sequences at their beginning (N-terminus) that consist of a string of 20 to 50 amino acids. These sequences are...
    53 KB (6,406 words) - 07:06, 12 November 2024