Neuroligin (NLGN), a type I membrane protein, is a cell adhesion protein on the postsynaptic membrane that mediates the formation and maintenance of synapses...

notably neuroligin, while the intracellular cytoplasmic portion interacts with proteins associated with exocytosis. Neurexin and neuroligin "shake hands...

Neuroligin-3 is a protein that in humans is encoded by the NLGN3 gene. This gene encodes a member of the neuroligin family of neuronal cell surface proteins...

Neuroligin-4, X-linked is a protein that in humans is encoded by the NLGN4X gene. In the human brain, the synaptic protein NLGN4 is primarily expressed...

made and helping to form a stable adhesion complex. synCAM1 along with neuroligin are the two CAM’s known to be sufficient to initiate the formation of...

Gillberg IC, et al. (May 2003). "Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism". Nature Genetics. 34 (1):...

researchers found an association between a maternal immune response to neuroligin 4 Y-linked protein (NLGN4Y) and subsequent sexual orientation in their...

mechanism of gay people who tend to have older brothers. They believed the Neuroligin 4 Y-linked protein was responsible for a later son being gay. They found...

Neuroligin-1 is a protein that in humans is encoded by the NLGN1 gene. This gene encodes a member of the neuroligin family of neuronal cell surface proteins...

this process such as neurexins, present on presynaptic neurons, and neuroligins, present on postsynaptic neurons, that come together to form a physical...

anchoring synaptic proteins. Its direct and indirect binding partners include neuroligin, NMDA receptors, AMPA receptors, and potassium channels. It plays an important...

Autism Speaks, is currently using mice to examine the potential role of neuroligin gene mutations in causing autism. Much research has been done into the...

NLGN may refer to: Neuroligin, a protein New Local Government Network, a think tank of the United Kingdom This disambiguation page lists articles associated...

Examples CA clan C1, C2, C19 Calpamodulin CD clan C14 CFLAR SC clan S9, S33 Neuroligin SK clan S14 ClpR SR clan S60 Serotransferrin domain 2 ST clan S54 RHBDF1...

polyposis coli (APC) multiprotein complex is required for localizing neuroligin and neurexin to neuronal nicotinic synapses in vivo". The Journal of Neuroscience...

not yet known. Neuroligins and SynCAM as synaptogenic signals: Sudhof, Serafini, Scheiffele and colleagues have shown that neuroligins and SynCAM can...

dendritic spine growth may be disrupted in autism due to impaired neurexin–neuroligin cell-adhesion signaling or dysregulated synthesis of synaptic proteins...

essential to formation and maintenance of connections between neurons, neuroligins found on postsynaptic neurons that bind presynaptic cell adhesion molecules...

membranes of inhibitory synapses by the trans-synaptic adhesion molecule neuroligin-2, where they provide the scaffold for the clustering of inhibitory postsynaptic...

mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin-neuroligin-mediated transsynaptic signaling". The Journal of Neuroscience. 32 (43):...

presynaptic membrane cell-adhesion molecules that bind primarily to neuroligins, proteins that have been associated with autism. Autism is characterized...

Neuroligin-2 is a protein that in humans is encoded by the NLGN2 gene. This gene encodes a member of a family of neuronal cell surface proteins. Members...

"Structures, alternative splicing, and neurexin binding of multiple neuroligins". J. Biol. Chem. 271 (5): 2676–2682. doi:10.1074/jbc.271.5.2676. PMID 8576240...

specifically, recent research (Jan 2018) has found maternal antibodies to the neuroligin NLGN4Y protein, a Y-chromosome protein important in male fetal brain development...

synapses. Peter Scheiffele discovered that the neuronal adhesion molecules neuroligin and neurexin play an important role in synapse formation. In his current...

Gillberg C, Bourgeron T (2003). "Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism". Nature Genetics. 34 (1):...

Hirao K, Takai Y, Rosahl TW, Südhof TC (September 1997). "Binding of neuroligins to PSD-95". Science. 277 (5331): 1511–5. doi:10.1126/science.277.5331...

and mammalian genomes. Shipman's neuroscience work focused primarily on neuroligin, a cell adhesion protein that plays a role in synaptic formation. Shipman...

in the birth of a son.": 24  Maternal antibodies against Y-chromosome neuroligin have been implicated in this effect, among other evidence that favours...

specializations that facilitate synaptogenesis. Indeed, a defect in genes encoding neuroligin, a cell-adhesion molecule found in the post-synaptic membrane, has been...