• Thumbnail for Ouabain
    Ouabain /wɑːˈbɑːɪn/ or /ˈwɑːbeɪn, ˈwæ-/ (from Somali waabaayo, "arrow poison" through French ouabaïo) also known as g-strophanthin, is a plant derived...
    23 KB (2,397 words) - 20:25, 14 May 2024
  • Thumbnail for Sodium–potassium pump
    classical ion transporting, this membrane protein can also relay extracellular ouabain-binding signalling into the cell through regulation of protein tyrosine...
    38 KB (4,367 words) - 16:52, 26 June 2024
  • Thumbnail for Ventricular escape beat
    escape rate Ouabain infusion decreases ventricular escape time and increases ventricular escape rhythm. However, a high dose of ouabain can lead to ventricular...
    6 KB (742 words) - 13:04, 23 May 2021
  • Strophanthus. The singular may refer to: g-Strophanthin, also known as ouabain k-Strophanthin Cardenolide This set index article lists chemical compounds...
    529 bytes (58 words) - 21:28, 25 April 2023
  • Thumbnail for Dystonia
    ouabain block of Na+ -K+ pumps in the cerebellum of a live mouse results in it displaying ataxia and dystonia. Ataxia is observed for lower ouabain concentrations...
    40 KB (3,522 words) - 17:36, 3 August 2024
  • Thumbnail for Cardiac glycoside
    toxicaria (upas tree): antiarin Strophanthus kombe (Strophanthus vine): ouabain (g-strophanthin) and other strophanthins Digitalis lanata and Digitalis...
    17 KB (1,844 words) - 02:12, 12 May 2024
  • Thumbnail for Strophanthus
    genus produce toxic alkaloids and cardiac glycosides g-strophanthin (syn. ouabain), k-strophanthin, and e-strophanthin. As ordinarily administered, the drug...
    6 KB (572 words) - 21:10, 22 June 2024
  • ouabain block of Na+ -K+ pumps in the cerebellum of a live mouse results in it displaying ataxia and dystonia. Ataxia is observed for lower ouabain concentrations...
    55 KB (5,946 words) - 00:23, 29 July 2024
  • Thumbnail for K-Strophanthidin
    genus Strophanthus. It is the aglycone of k-strophanthin, an analogue of ouabain. k-strophanthin is found in the ripe seeds of Strophanthus kombé and in...
    15 KB (1,759 words) - 14:56, 9 December 2023
  • Thumbnail for Jens Christian Skou
    Post asked whether the enzyme was inhibited by ouabain. At this stage Skou was unaware that ouabain inhibited the pump, but he immediately telephoned...
    11 KB (1,248 words) - 22:05, 17 January 2024
  • Thumbnail for Digitalis purpurea
    However, digitoxin, digoxin and several other cardiac glycosides, such as ouabain, are known to have steep dose-response curves, i.e., minute increases in...
    26 KB (2,495 words) - 23:11, 11 July 2024
  • Thumbnail for Rostafuroxin
    Giuseppe (2006). "Rostafuroxin: An ouabain antagonist that corrects renal and vascular Na+-K+- ATPase alterations in ouabain and adducin-dependent hypertension"...
    2 KB (150 words) - 00:28, 7 May 2023
  • Thumbnail for Somerton Man
    the purchase. (The drugs were later publicly identified as digitalis and ouabain, both cardenolide-type cardiac glycosides.) Hicks noted the only "fact"...
    110 KB (12,749 words) - 10:35, 9 August 2024
  • Thumbnail for Atovaquone
    PMID 11078770. Farag A, Wang P, et al. (May 2020). "Identification of Atovaquone, Ouabain and Mebendazole as FDA-Approved Drugs Targeting SARS-CoV-2". chemRxiv (preprint)...
    11 KB (880 words) - 06:06, 11 May 2024
  • Nitrogen dioxide N-Nitrosodimethylamine Norbormide Organorhodium complex Ouabain Oxamyl Oxetane, 3,3-bis(chloromethyl)- Oxydisulfoton Paraquat Paraquat...
    10 KB (825 words) - 19:18, 7 August 2024
  • Thumbnail for Strophanthus gratus
    Tobago. Strophanthus gratus has been used in local traditional medicine: ouabain derived from the plant's seeds is used as a treatment for heart failure...
    2 KB (151 words) - 22:52, 12 December 2023
  • Cintrat JC, Le Pavec G, Delaunay-Moisan A, et al. (September 2021). "Ouabain and chloroquine trigger senolysis of BRAF-V600E-induced senescent cells...
    26 KB (2,028 words) - 10:24, 8 June 2024
  • Strophanthin is the name given to two different compounds, g-strophanthin (ouabain) obtained from Strophanthus gratus and k-strophanthin from Stroph. kombé...
    9 KB (1,116 words) - 18:53, 26 July 2023
  • Thumbnail for Acokanthera
    also occurs in Yemen. Its sap contains the deadly cardiotoxic glycoside ouabain. The sap is among the most commonly used in arrow poisons, including those...
    3 KB (199 words) - 14:22, 14 May 2024
  • Thesis Metabolism and ion transport of frog skin: biological effects of ouabain (1966) Academic work Discipline Neuropharmacology Institutions Lilly Research...
    7 KB (658 words) - 19:43, 15 July 2024
  • Thumbnail for Calotropis gigantea
    Sodium Current Improves Cardiac Function during Sodium Pump Inhibition by Ouabain". Journal of Pharmacology and Experimental Therapeutics. 337 (2): 513–523...
    21 KB (2,361 words) - 09:05, 13 April 2024
  • Thumbnail for Ozone
    2006-09-25. Retrieved 2006-10-11. Smith, LL (2004). "Oxygen, oxysterols, ouabain, and ozone: a cautionary tale". Free Radical Biology & Medicine. 37 (3):...
    150 KB (18,169 words) - 21:47, 8 August 2024
  • Thumbnail for Quinidine
    binding to the same receptor sites as the digitalis glycosides such as ouabain. The effect of quinidine on the ion channels is to prolong the cardiac...
    19 KB (1,862 words) - 01:53, 8 April 2024
  • Thumbnail for List of poisonous plants
    Strophanthus gratus Apocynaceae The ripe seeds of this African plant contain ouabain, a potent cardiac glycoside that, when sufficiently concentrated, can induce...
    141 KB (4,901 words) - 03:57, 16 May 2024
  • Thumbnail for Methylene blue
    incompletely understood; vital staining of nerve fibers in skin is prevented by ouabain, a drug that inhibits the Na/K-ATPase of cell membranes. Methylene blue...
    53 KB (5,613 words) - 08:41, 16 May 2024
  • Thumbnail for Albert Fraenkel
    pneumoniae as a cause of bacterial pneumonia and championed intravenous ouabain for use in heart failure. The Albert-Fraenkel-Plakette (Albert Fraenkel...
    2 KB (205 words) - 00:08, 27 January 2022
  • sides. Maya bowmen were armed with spears. They tipped their arrows with ouabain, a poison which caused death by cardiac arrest or respiratory failure....
    5 KB (515 words) - 02:18, 10 August 2024
  • plants that contain cardiac glycosides, such as Acokanthera (possessing ouabain), oleander (Nerium oleander), milkweeds (Asclepias), or Strophanthus, all...
    15 KB (1,734 words) - 08:00, 28 July 2024
  • Thumbnail for Venomous mammal
    (Acokanthera schimperi), so-called because human hunters extract a toxin, ouabain, to coat arrows that can kill an elephant. After the rat has chewed the...
    30 KB (3,587 words) - 10:42, 3 August 2024
  • Thumbnail for Oleandrin
    like ouabain and digoxin but has less effect than digoxin. It is however, just like its derivate oleandrigenin, a more potent glycoside than ouabain. Oleandrin...
    26 KB (2,686 words) - 05:15, 13 May 2024