inhibitors Kunitz STI protease inhibitor Classes of inhibitor mechanisms of action are: Suicide inhibitor Transition state inhibitor Protein protease...

Protease inhibitor can refer to: Protease inhibitor (pharmacology): a class of medication that inhibits viral protease Protease inhibitor (biology): molecules...

Map Proteases in angiogenesis Intramembrane proteases Protease inhibitor (pharmacology) Protease inhibitor (biology) TopFIND - database of protease specificity...

(pharmacology) Protease inhibitor (biology) TopFIND – database of protease specificity, substrates, products and inhibitors MEROPS – database of protease evolutionary...

A trypsin inhibitor (TI) is a protein and a type of serine protease inhibitor (serpin) that reduces the biological activity of trypsin by controlling...

serpin proteinase inhibitor 6 is expressed in monocytes and granulocytes and is a potent inhibitor of the azurophilic granule protease, cathepsin G". Blood...

angiogenesis Intramembrane proteases Protease inhibitor (pharmacology) Protease inhibitor (biology) TopFIND - database of protease specificity, substrates...

first protease inhibitor, saquinavir. Following that discovery, other HIV protease inhibitors were designed using the same principle. The HIV protease is...

(pharmacology) Protease inhibitor (biology) TopFIND - database of protease specificity, substrates, products and inhibitors MEROPS - database of protease evolutionary...

However, not all inhibitors are based on the structures of substrates. For example, the structure of another HIV protease inhibitor tipranavir is not...

considering that changes to a few amino acids within HIV protease can render it much less visible to an inhibitor, the active site of this enzyme can change rapidly...

C1-inhibitor (C1-inh, C1 esterase inhibitor) is a protease inhibitor belonging to the serpin superfamily. Its main function is the inhibition of the complement...

immunodeficiency Protease inhibitor (pharmacology), class of drugs used to treat or prevent infection by viruses, including HIV and Hepatitis C Protease inhibitor (biology)...

molecular biology the protein SSI is a Subtilisin inhibitor-like which stands for Streptomyces subtilisin inhibitor. This is a protease inhibitor. These...

non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance". Journal of Molecular Biology. 284 (2): 313–23...

In molecular biology, Proteinase K (EC 3.4.21.64, protease K, endopeptidase K, Tritirachium alkaline proteinase, Tritirachium album serine proteinase...

of these inhibitors act to block caspases, a family of cysteine proteases that play an integral role in apoptosis. Some of these inhibitors include the...

3C-like protease (3CLpro) or main protease (Mpro), formally known as C30 endopeptidase or 3-chymotrypsin-like protease, is the main protease found in...

Plasminogen activator inhibitor-2 (placental PAI, SerpinB2, PAI-2), a serine protease inhibitor of the serpin superfamily, is a coagulation factor that...

three proteases: P1 protease (1 cleavage site), helper-component protease (1 cleavage site) and TEV protease (7 cleavage sites). The native TEV protease also...

important inhibitors of urokinase are the serpins plasminogen activator inhibitor-1 (PAI-1) and plasminogen activator inhibitor-2 (PAI-2), which inhibit the...

A protease inhibitor, it is also known as alpha1–proteinase inhibitor (A1PI) or alpha1-antiproteinase (A1AP) because it inhibits various proteases (not...

as a protease inhibitor, especially in molecular biology applications. PCMB reacts with thiol groups in proteins and is therefore an inhibitor of enzymes...

medication developed by Pfizer which acts as an orally active 3C-like protease inhibitor. It is part of a nirmatrelvir/ritonavir combination used to treat...

immunodeficiency virus HIV-1 protease inhibitor (Ki = 2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of...

molecular biology, the Bowman–Birk protease inhibitor family of proteins consists of eukaryotic proteinase inhibitors, belonging to MEROPS inhibitor family...

Diisopropyl fluorophosphate (DIFP) is an irreversible inhibitor that blocks the action of serine protease. When it binds to the enzyme a nucleophilic substitution...

In plant biology, proteinase inhibitors are a family of small proteins that serve an integral role in the plant’s defense mechanisms against herbivory...

activation of protease-activated receptors on the cell membrane of the platelet. Thrombin bound to thrombomodulin activates protein C, an inhibitor of the coagulation...

"Selective irreversible inhibition of a protease by targeting a noncatalytic cysteine". Nature Chemical Biology. 7 (1): 22–24. doi:10.1038/nchembio.492...