Purine is a heterocyclic aromatic organic compound that consists of two rings (pyrimidine and imidazole) fused together. It is water-soluble. Purine also...

Purine metabolism refers to the metabolic pathways to synthesize and break down purines that are present in many organisms. Purines are biologically synthesized...

Purine analogues are antimetabolites that mimic the structure of metabolic purines. Nucleobase analogues Thiopurines such as thioguanine are used to treat...

linked. Purines, however, are first synthesized from the sugar template onto which the ring synthesis occurs. For reference, the syntheses of the purine and...

Purine synthesis may either refer to: in vivo purine synthesis: Purine metabolism#Biosynthesis laboratory purine synthesis: Purine#Laboratory synthesis...

have a fused-ring skeletal structure derived of purine, hence they are called purine bases. The purine nitrogenous bases are characterized by their single...

A purine riboswitch is a sequence of ribonucleotides in certain messenger RNA (mRNA) that selectively binds to purine ligands via a natural aptamer domain...

archaically xanthic acid; systematic name 3,7-dihydropurine-2,6-dione) is a purine base found in most human body tissues and fluids, as well as in other organisms...

inhibition of phosphodiesterase. Caffeine is a bitter, white crystalline purine, a methylxanthine alkaloid, and is chemically related to the adenine and...

ammonium acid urate. Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine. High blood concentrations...

In enzymology, a purine nucleosidase (EC 3.2.2.1) is an enzyme that catalyzes the chemical reaction a purine nucleoside + H2O ⇌ {\displaystyle \rightleftharpoons...

This group includes terpene-like and steroid-like alkaloids, as well as purine-like alkaloids such as caffeine, theobromine, theacrine and theophylline...

class is nucleoside:purine(pyrimidine) deoxy-D-ribosyltransferase. Other names in common use include purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyl...

Adenine (/ˈædɪnɪn/) (symbol A or Ade) is a purine nucleotide base. It is one of the four nucleobases in the nucleic acids of DNA, the other three being...

Purine nucleoside phosphorylase, PNP, PNPase or inosine phosphorylase (EC 2.4.2.1) is an enzyme that in humans is encoded by the NP gene. It catalyzes...

allopurinol's effect. Allopurinol is a purine analog; it is a structural isomer of hypoxanthine (a naturally occurring purine in the body) and is an inhibitor...

1-pyrophosphate (PRPP) to the purine. HGPRT plays a central role in the generation of purine nucleotides through the purine salvage pathway. HGPRT catalyzes...

of hypoxanthine and the first nucleotide formed during the synthesis of purine nucleotides. It can also be formed by the deamination of adenosine monophosphate...

The Purine Nucleotide Cycle is a metabolic pathway in protein metabolism requiring the amino acids aspartate and glutamate. The cycle is used to regulate...

Methylliberine Names Preferred IUPAC name 2-Methoxy-1,7,9-trimethyl-7,9-dihydro-1H-purine-6,8-dione Other names O(2),1,7,9-Tetramethylurate; Tetramethyluric acid;...

enzymology, a diphosphate-purine nucleoside kinase (EC 2.7.1.143) is an enzyme that catalyzes the chemical reaction diphosphate + a purine nucleoside ⇌ {\displaystyle...

often refers to nucleotide salvage in particular, in which nucleotides (purine and pyrimidine) are synthesized from intermediates in their degradative...

phosphate, and a nitrogenous base. The bases found in nucleic acids are either purines or pyrimidines. In the more complex multicellular animals, they are both...

Theacrine, also known as 1,3,7,9-tetramethyluric acid, is a purine alkaloid found in Cupuaçu (Theobroma grandiflorum) and in a Chinese tea known as kucha...

the anomeric carbon is linked through a glycosidic bond to the N9 of a purine or the N1 of a pyrimidine. Nucleotides are the molecular building blocks...

this set of white cells (which cannot operate purine salvage pathways) is selectively targeted by the purine deficiency resulting from inosine monophosphate...

Purine-rich element binding protein G is a protein that in humans is encoded by the PURG gene. The exact function of this gene is not known, however, its...

zolesuccinocarboxamide (SAICAR) is an intermediate in the formation of purines. The conversion of ATP, L-aspartate, and 5-aminoimidazole-4-carboxyribonucleotide...

amount of urate in the body depends on the balance between the amount of purines eaten in food, the amount of urate synthesised within the body (e.g., through...

established; purine–purine pairings are energetically unfavorable because the molecules are too close, leading to overlap repulsion. Purine–pyrimidine base-pairing...