Purine is a heterocyclic aromatic organic compound that consists of two rings (pyrimidine and imidazole) fused together. It is water-soluble. Purine also...
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Purine metabolism refers to the metabolic pathways to synthesize and break down purines that are present in many organisms. Purines are biologically synthesized...
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Purine analogues are antimetabolites that mimic the structure of metabolic purines. Nucleobase analogues Thiopurines such as thioguanine are used to treat...
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Nucleotide (section Purine ribonucleotide synthesis)
linked. Purines, however, are first synthesized from the sugar template onto which the ring synthesis occurs. For reference, the syntheses of the purine and...
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Purine synthesis may either refer to: in vivo purine synthesis: Purine metabolism#Biosynthesis laboratory purine synthesis: Purine#Laboratory synthesis...
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Nucleotide base (section Modified purine nucleobases)
have a fused-ring skeletal structure derived of purine, hence they are called purine bases. The purine nitrogenous bases are characterized by their single...
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A purine riboswitch is a sequence of ribonucleotides in certain messenger RNA (mRNA) that selectively binds to purine ligands via a natural aptamer domain...
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Xanthine (redirect from 1H-purine-2,6-diol)
archaically xanthic acid; systematic name 3,7-dihydropurine-2,6-dione) is a purine base found in most human body tissues and fluids, as well as in other organisms...
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Caffeine (redirect from 1,3,7-trimethyl-1H-purine-2,6(3H,7H)-dione 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione)
inhibition of phosphodiesterase. Caffeine is a bitter, white crystalline purine, a methylxanthine alkaloid, and is chemically related to the adenine and...
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ammonium acid urate. Uric acid is a product of the metabolic breakdown of purine nucleotides, and it is a normal component of urine. High blood concentrations...
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In enzymology, a purine nucleosidase (EC 3.2.2.1) is an enzyme that catalyzes the chemical reaction a purine nucleoside + H2O ⇌ {\displaystyle \rightleftharpoons...
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Alkaloid (redirect from Purine alkaloid)
This group includes terpene-like and steroid-like alkaloids, as well as purine-like alkaloids such as caffeine, theobromine, theacrine and theophylline...
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Nucleoside deoxyribosyltransferase (redirect from Nucleoside:purine(pyrimidine) deoxy-D-ribosyltransferase)
class is nucleoside:purine(pyrimidine) deoxy-D-ribosyltransferase. Other names in common use include purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyl...
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Adenine (redirect from 6-Amino-purine)
Adenine (/ˈædɪnɪn/) (symbol A or Ade) is a purine nucleotide base. It is one of the four nucleobases in the nucleic acids of DNA, the other three being...
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Purine nucleoside phosphorylase, PNP, PNPase or inosine phosphorylase (EC 2.4.2.1) is an enzyme that in humans is encoded by the NP gene. It catalyzes...
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allopurinol's effect. Allopurinol is a purine analog; it is a structural isomer of hypoxanthine (a naturally occurring purine in the body) and is an inhibitor...
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1-pyrophosphate (PRPP) to the purine. HGPRT plays a central role in the generation of purine nucleotides through the purine salvage pathway. HGPRT catalyzes...
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Inosinic acid (category Purines)
of hypoxanthine and the first nucleotide formed during the synthesis of purine nucleotides. It can also be formed by the deamination of adenosine monophosphate...
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The Purine Nucleotide Cycle is a metabolic pathway in protein metabolism requiring the amino acids aspartate and glutamate. The cycle is used to regulate...
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Methylliberine Names Preferred IUPAC name 2-Methoxy-1,7,9-trimethyl-7,9-dihydro-1H-purine-6,8-dione Other names O(2),1,7,9-Tetramethylurate; Tetramethyluric acid;...
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enzymology, a diphosphate-purine nucleoside kinase (EC 2.7.1.143) is an enzyme that catalyzes the chemical reaction diphosphate + a purine nucleoside ⇌ {\displaystyle...
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Nucleotide salvage (redirect from Purine salvage pathway)
often refers to nucleotide salvage in particular, in which nucleotides (purine and pyrimidine) are synthesized from intermediates in their degradative...
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Nucleic acid metabolism (category Purines)
phosphate, and a nitrogenous base. The bases found in nucleic acids are either purines or pyrimidines. In the more complex multicellular animals, they are both...
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Theacrine (redirect from 1,3,7,9-Tetramethyl-7,9-dihydro-1H-purine-2,6,8(3H)-trione)
Theacrine, also known as 1,3,7,9-tetramethyluric acid, is a purine alkaloid found in Cupuaçu (Theobroma grandiflorum) and in a Chinese tea known as kucha...
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the anomeric carbon is linked through a glycosidic bond to the N9 of a purine or the N1 of a pyrimidine. Nucleotides are the molecular building blocks...
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Inosine (category Purines)
this set of white cells (which cannot operate purine salvage pathways) is selectively targeted by the purine deficiency resulting from inosine monophosphate...
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Purine-rich element binding protein G is a protein that in humans is encoded by the PURG gene. The exact function of this gene is not known, however, its...
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zolesuccinocarboxamide (SAICAR) is an intermediate in the formation of purines. The conversion of ATP, L-aspartate, and 5-aminoimidazole-4-carboxyribonucleotide...
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Hyperuricemia (category Inborn errors of purine-pyrimidine metabolism)
amount of urate in the body depends on the balance between the amount of purines eaten in food, the amount of urate synthesised within the body (e.g., through...
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established; purine–purine pairings are energetically unfavorable because the molecules are too close, leading to overlap repulsion. Purine–pyrimidine base-pairing...
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