Pyrimidine (C4H4N2; /pɪˈrɪ.mɪˌdiːn, paɪˈrɪ.mɪˌdiːn/) is an aromatic, heterocyclic, organic compound similar to pyridine (C5H5N). One of the three diazines...
23 KB (2,105 words) - 19:49, 4 December 2024
Pyrimidine dimers represent molecular lesions originating from thymine or cytosine bases within DNA, resulting from photochemical reactions. These lesions...
16 KB (1,947 words) - 15:06, 24 November 2024
The purine bases adenine and guanine and pyrimidine base cytosine occur in both DNA and RNA, while the pyrimidine bases thymine (in DNA) and uracil (in RNA)...
32 KB (3,305 words) - 19:08, 12 December 2024
of cytosine, uracil, and thymine is derived of pyrimidine, so those three bases are called the pyrimidine bases. Each of the base pairs in a typical double-helix...
15 KB (1,439 words) - 03:19, 11 November 2024
Pyrimidine biosynthesis occurs both in the body and through organic synthesis. De Novo biosynthesis of a pyrimidine is catalyzed by three gene products...
9 KB (771 words) - 13:58, 17 June 2024
Pyrimidine analogues are antimetabolites which mimic the structure of metabolic pyrimidines. Nucleobase analogues Fluorouracil (5FU), which inhibits thymidylate...
1 KB (83 words) - 04:27, 4 June 2024
RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached...
10 KB (906 words) - 19:45, 16 December 2024
In enzymology, a pyrimidine-5'-nucleotide nucleosidase (EC 3.2.2.10) is an enzyme that catalyzes the chemical reaction a pyrimidine 5'-nucleotide + H2O...
2 KB (186 words) - 15:38, 26 August 2023
In enzymology, a pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) is an enzyme that catalyzes the chemical reaction a pyrimidine nucleoside + phosphate...
2 KB (220 words) - 17:19, 22 September 2024
Nucleoside deoxyribosyltransferase (redirect from Nucleoside:purine(pyrimidine) deoxy-D-ribosyltransferase)
nucleoside:purine(pyrimidine) deoxy-D-ribosyltransferase. Other names in common use include purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyl...
3 KB (267 words) - 16:18, 22 September 2024
Uracil (redirect from 2-oxy-4-oxy pyrimidine)
demethylated form of thymine. Uracil is a common and naturally occurring pyrimidine derivative. The name "uracil" was coined in 1885 by the German chemist...
29 KB (2,951 words) - 03:46, 11 December 2024
Nucleic acid metabolism (category Pyrimidines)
nitrogenous base. The bases found in nucleic acids are either purines or pyrimidines. In the more complex multicellular animals, they are both primarily produced...
13 KB (1,457 words) - 22:06, 24 December 2023
a heterocyclic aromatic organic compound that consists of two rings (pyrimidine and imidazole) fused together. It is water-soluble. Purine also gives...
24 KB (2,506 words) - 20:00, 4 December 2024
Ribosylpyrimidine nucleosidase (redirect from Pyrimidine-nucleoside ribohydrolase)
pyrimidine nucleoside + H2O ⇌ {\displaystyle \rightleftharpoons } D-ribose + a pyrimidine base Thus, the two substrates of this enzyme are pyrimidine...
3 KB (278 words) - 15:45, 22 September 2024
Deoxyribonuclease (pyrimidine dimer) (EC 3.1.25.1, endodeoxyribonuclease (pyrimidine dimer), bacteriophage T4 endodeoxyribonuclease V, T4 endonuclease...
2 KB (148 words) - 13:47, 26 August 2023
linked through a glycosidic bond to the N9 of a purine or the N1 of a pyrimidine. Nucleotides are the molecular building blocks of DNA and RNA. This list...
10 KB (813 words) - 19:42, 12 August 2024
(OPRTase) or orotic acid phosphoribosyltransferase is an enzyme involved in pyrimidine biosynthesis. It catalyzes the formation of orotidine 5'-monophosphate...
18 KB (1,867 words) - 19:23, 22 July 2024
Photolyase (redirect from Deoxyribocyclobutadipyrimidine pyrimidine-lyase)
is called photoreactivation. They mainly convert pyrimidine dimers into a normal pair of pyrimidine bases. Photo reactivation, the first DNA repair mechanism...
15 KB (1,759 words) - 05:16, 23 September 2024
Dimerization (section Pyrimidine dimers)
radical (C5H5)Cr(CO)3. Pyrimidine dimers (also known as thymine dimers) are formed by a photochemical reaction from pyrimidine DNA bases when exposed...
12 KB (1,298 words) - 04:28, 1 January 2025
Pyrimidine phosphorylase may refer to: Thymidine phosphorylase Uridine phosphorylase This set index article includes a list of related items that share...
410 bytes (49 words) - 08:17, 7 November 2019
orotidine-5'-monophosphate (OMP). A distinguishing characteristic of pyrimidine synthesis is that the pyrimidine ring is fully synthesized before being attached to the...
9 KB (922 words) - 10:51, 23 January 2024
governed by physico-chemical processes. RNA is composed of purine and pyrimidine nucleotides, both of which are necessary for reliable information transfer...
4 KB (467 words) - 14:44, 14 July 2024
endonucleosidase (EC 3.2.2.17, pyrimidine dimer DNA-glycosylase, endonuclease V, deoxyribonucleate pyrimidine dimer glycosidase, pyrimidine dimer DNA glycosylase...
2 KB (165 words) - 13:47, 26 August 2023
Pyrimidine oxygenase (EC 1.14.99.46, RutA) is an enzyme with systematic name uracil,FMNH2:oxygen oxidoreductase (uracil hydroxylating, ring-opening). This...
2 KB (159 words) - 15:38, 26 August 2023
Orotic aciduria (redirect from Orotic aciduria purines-pyrimidines)
decreased ability to synthesize pyrimidines. It was the first described enzyme deficiency of the de novo pyrimidine synthesis pathway. Orotic aciduria...
6 KB (585 words) - 15:13, 25 October 2024
single-ringed chemical structures called pyrimidines. Purines are complementary only with pyrimidines: pyrimidine–pyrimidine pairings are energetically unfavorable...
32 KB (3,701 words) - 14:01, 27 November 2024
adenine, guanine, and cytosine. Thymine is also known as 5-methyluracil, a pyrimidine nucleobase. In RNA, thymine is replaced by the nucleobase uracil. Thymine...
11 KB (889 words) - 19:26, 3 December 2024
structure: Pyrimidines are six-membered heterocyclic with nitrogen atoms in position 1 and 3. Purines are bicyclic, consisting of a pyrimidine fused to...
49 KB (5,299 words) - 15:13, 30 December 2024
Nucleotide salvage (section Pyrimidines)
to nucleotide salvage in particular, in which nucleotides (purine and pyrimidine) are synthesized from intermediates in their degradative pathway. Nucleotide...
7 KB (736 words) - 10:22, 12 August 2024
divided into two groups, the single-ringed pyrimidines and the double-ringed purines. In DNA, the pyrimidines are thymine and cytosine; the purines are...
166 KB (17,843 words) - 18:18, 22 December 2024