• Thumbnail for Pyruvate dehydrogenase kinase
    Pyruvate dehydrogenase kinase (also pyruvate dehydrogenase complex kinase, PDC kinase, or PDK; EC 2.7.11.2) is a kinase enzyme which acts to inactivate...
    14 KB (1,711 words) - 16:27, 25 October 2023
  • Thumbnail for Pyruvate dehydrogenase
    Pyruvate dehydrogenase is an enzyme that catalyzes the reaction of pyruvate and a lipoamide to give the acetylated dihydrolipoamide and carbon dioxide...
    13 KB (1,279 words) - 22:46, 18 July 2024
  • Thumbnail for PDK4
    Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial (PDK4) is an enzyme that in humans is encoded by the PDK4 gene. It codes for an isozyme...
    20 KB (2,535 words) - 17:29, 31 May 2023
  • Thumbnail for Pyruvate dehydrogenase complex
    Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that converts pyruvate into acetyl-CoA by a process called pyruvate decarboxylation...
    29 KB (3,340 words) - 20:01, 15 August 2024
  • Thumbnail for Pyruvate dehydrogenase lipoamide kinase isozyme 1
    Pyruvate dehydrogenase lipoamide kinase isozyme 1, mitochondrial is an enzyme that in humans is encoded by the PDK1 gene. It codes for an isozyme of pyruvate...
    12 KB (1,616 words) - 09:57, 3 June 2024
  • Thumbnail for PDK2
    Pyruvate dehydrogenase kinase isoform 2 (PDK2) also known as pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial is an enzyme that in humans...
    16 KB (1,929 words) - 07:41, 4 January 2024
  • Thumbnail for PDK3
    Pyruvate dehydrogenase lipoamide kinase isozyme 3, mitochondrial is an enzyme that in humans is encoded by the PDK3 gene. It codes for an isozyme of pyruvate...
    13 KB (1,575 words) - 02:39, 19 December 2023
  • Thumbnail for Tumor hypoxia
    dehydrogenase (GAPDH), phosphoglycerate kinase (PGK), phosphoglycerate mutase (PGM), enolase 1 (ENOA), pyruvate kinase (PK), pyruvate dehydrogenase kinase...
    52 KB (5,517 words) - 00:16, 7 June 2024
  • Thumbnail for Dihydrolipoyl transacetylase
    component of the multienzyme pyruvate dehydrogenase complex. The pyruvate dehydrogenase complex is responsible for the pyruvate decarboxylation step that...
    21 KB (2,487 words) - 00:19, 8 June 2024
  • Thumbnail for Pyruvate dehydrogenase phosphatase
    reverse the effects of pyruvate dehydrogenase kinase upon pyruvate dehydrogenase, activating pyruvate dehydrogenase. Pyruvate dehydrogenase (E1) is one of the...
    10 KB (1,182 words) - 20:23, 10 November 2022
  • Thumbnail for Acetyl-CoA
    Allosteric regulator Acetyl-CoA serves as an allosteric regulator of pyruvate dehydrogenase kinase (PDK). It regulates through the ratio of acetyl-CoA versus CoA...
    22 KB (2,097 words) - 07:31, 11 September 2024
  • Thumbnail for Tumor metabolome
    HIF1 then would activate the pyruvate dehydrogenase kinase (PDKs), which inactivate the mitochondrial pyruvate dehydrogenase complex. It reduces the flow...
    22 KB (2,576 words) - 03:03, 28 November 2023
  • Thumbnail for AMP-activated protein kinase
    5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular...
    65 KB (7,149 words) - 04:45, 26 August 2024
  • Thumbnail for Cyclin-dependent kinase
    Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression...
    35 KB (3,829 words) - 14:24, 17 June 2024
  • Pyruvic acid (redirect from Pyruvate)
    "GlycolysisGluconeogenesis_WP534". Pyruvate decarboxylation by the pyruvate dehydrogenase complex produces acetyl-CoA. Carboxylation by pyruvate carboxylase produces...
    16 KB (1,254 words) - 08:39, 19 July 2024
  • Thumbnail for Protein kinase B
    Protein kinase B (PKB), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple...
    35 KB (3,831 words) - 18:08, 20 August 2024
  • A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses...
    46 KB (5,492 words) - 14:52, 20 August 2024
  • Thumbnail for Protein kinase A
    important in metabolism. For example, protein kinase A phosphorylates acetyl-CoA carboxylase and pyruvate dehydrogenase. Such covalent modification has an inhibitory...
    27 KB (2,665 words) - 17:03, 6 April 2024
  • biology, extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that...
    11 KB (1,128 words) - 19:03, 18 September 2023
  • structural analog of pyruvate and activates the pyruvate dehydrogenase complex (PDC) to inhibit pyruvate dehydrogenase kinases, to keep the complex in...
    26 KB (3,172 words) - 03:56, 1 September 2024
  • Polydiketoenamine, a polymer Phosphoinositide-dependent kinase Pyruvate dehydrogenase kinase PDK (Namibian music group) This disambiguation page lists...
    867 bytes (112 words) - 01:45, 23 June 2023
  • studied as potential drugs because they inhibit the enzyme pyruvate dehydrogenase kinase. Although preliminary studies found that DCA can slow the growth...
    22 KB (1,954 words) - 23:33, 14 June 2024
  • Thumbnail for Pyruvate dehydrogenase (lipoamide) beta
    Pyruvate dehydrogenase (lipoamide) beta, also known as pyruvate dehydrogenase E1 component subunit beta, mitochondrial or PDHE1-B is an enzyme that in...
    20 KB (2,645 words) - 00:23, 8 June 2024
  • Thumbnail for Serine/threonine-specific protein kinase
    A serine/threonine protein kinase (EC 2.7.11.-) is a kinase enzyme, in particular a protein kinase, that phosphorylates the OH group of the amino-acid...
    14 KB (1,210 words) - 13:35, 14 June 2024
  • Thumbnail for Cyclin-dependent kinase 2
    Cyclin-dependent kinase 2, also known as cell division protein kinase 2, or Cdk2, is an enzyme that in humans is encoded by the CDK2 gene. The protein...
    35 KB (4,314 words) - 00:26, 6 July 2024
  • Thumbnail for Pyruvate dehydrogenase (lipoamide) alpha 1
    Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial is an enzyme that in humans is encoded by the PDHA1 gene.The pyruvate dehydrogenase...
    22 KB (2,885 words) - 20:23, 2 January 2024
  • transduction MAP kinase MAP kinase kinase kinase MAP kinase kinase kinase kinase Dérijard B, et al. (1995). "Independent human MAP-kinase signal transduction...
    3 KB (296 words) - 17:06, 14 September 2023
  • Thumbnail for C-Jun N-terminal kinases
    c-Jun N-terminal kinases (JNKs), were originally identified as kinases that bind and phosphorylate c-Jun on Ser-63 and Ser-73 within its transcriptional...
    14 KB (1,626 words) - 20:50, 30 May 2024
  • Thumbnail for MTOR
    a kinase that in humans is encoded by the MTOR gene. mTOR is a member of the phosphatidylinositol 3-kinase-related kinase family of protein kinases. mTOR...
    119 KB (12,654 words) - 00:05, 31 July 2024
  • In cell biology, Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling...
    27 KB (2,716 words) - 12:30, 12 September 2024