• The FriedelCrafts reactions are a set of reactions developed by Charles Friedel and James Crafts in 1877 to attach substituents to an aromatic ring....
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  • Thumbnail for James Crafts
    alkylation and acylation reactions with Charles Friedel in 1876. James Crafts, the son of Royal Altamont Crafts and Marianne Mason (daughter of Senator Jeremiah...
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  • Thumbnail for Charles Friedel
    and mineralogy at the Sorbonne. Friedel developed the Friedel-Crafts alkylation and acylation reactions with James Crafts in 1877, and attempted to make...
    5 KB (306 words) - 22:36, 5 July 2024
  • sulfonation, alkylation FriedelCrafts reaction and acylation FriedelCrafts reaction. The most widely practised example of this reaction is the ethylation...
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  • Friedel-Crafts reaction Friedel family, a rich lineage of French scientists: Charles Friedel (1832–1899), French chemist known for the Friedel-Crafts...
    19 KB (1,981 words) - 17:20, 27 November 2023
  • attack arenes. Acylium ions are intermediates in several reactions, such as the Friedel-Crafts acylation of arenes by acetyl chloride in the presence of...
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  • Lewis acid catalysis (category Chemical reactions)
    reactions involving carbon–carbon or carbon–heteroatom bond formation can be catalyzed by Lewis acids. Examples include the Friedel-Crafts reaction,...
    45 KB (5,026 words) - 04:16, 15 October 2024
  • for the German chemist Ludwig Gattermann and is similar to the FriedelCrafts reaction. Modifications have shown that it is possible to use sodium cyanide...
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  • Thumbnail for Leaving group
    Leaving group (category Reaction mechanisms)
    in the Friedel-Crafts reaction. Here, a strong Lewis acid is required to generate either a carbocation from an alkyl halide in the Friedel-Crafts alkylation...
    22 KB (2,532 words) - 15:42, 14 February 2024
  • The Zone of Interest (film) (category CS1 German-language sources (de))
    home in the "Zone of Interest" next to the concentration camp. Christian Friedel stars as Rudolf Höss alongside Sandra Hüller as Hedwig Höss. Development...
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  • Thumbnail for 1-Tetralone
    1-Tetralone (category CS1 German-language sources (de))
    3-Benzoylpropanoic acid itself can be obtained by a Haworth reaction (a variant of the Friedel-Crafts reaction) from benzene and succinic anhydride. The intramolecular...
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  • Thumbnail for Alkylbenzene
    extensive biodegradable yield over BAB-based sulfonates in the 1960s. Friedel-Crafts alkylation: alkylbenzenes can be synthesized from olefins or alkyl halides...
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  • Thumbnail for Georges Friedel
    the FriedelCrafts reaction Georges Friedel (1865–1933), here above described, French crystallographer and mineralogist; son of Charles Edmond Friedel (1895–1972)...
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  • moderately and strongly deactivated substrates that are inert to Friedel-Crafts reactions like acetophenone, nitrobenzene and p-chloronitrobenzene do show...
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  • Thumbnail for 2-Acetylfuran
    1914 via the reaction of the methyl Grignard reagent on 2-furonitrile. Modern industrial synthesis generally involves the FriedelCrafts acylation of...
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  • Frankland–Duppa reaction Fráter–Seebach alkylation Free radical halogenation Freund reaction FriedelCrafts acylation FriedelCrafts alkylation Friedländer...
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  • Tin(IV) chloride (category CS1 German-language sources (de))
    dibutyltin dilaurate) and polymer stabilizers. SnCl4 is used in FriedelCrafts reactions as a Lewis acid catalyst. For example, the acetylation of thiophene...
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  • Thumbnail for Tosyl group
    not tennessine. Reaction sequence: organic reduction of ethyl benzoylacetate by sodium borohydride to a diol, followed by Friedel-Crafts alkylation with...
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  • Thumbnail for Hydroquinone
    is highly susceptible to ring substitution by FriedelCrafts reactions such as alkylation. This reaction is exploited en route to popular antioxidants...
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  • Thumbnail for Oxalyl chloride
    chloride to give the corresponding acyl chloride in a process known as a Friedel-Crafts acylation. The resulting acyl chloride can be hydrolysed to form the...
    11 KB (906 words) - 12:28, 2 November 2024
  • Thumbnail for Diphenyl ether
    Diphenyl ether (category CS1 German-language sources (de))
    reactions. The compound undergoes reactions typical of other phenyl rings, including hydroxylation, nitration, halogenation, sulfonation, and Friedel–Crafts...
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  • Thumbnail for 3-Chloromethcathinone
    controlled, this precursor can be prepared by a standard Friedel-Crafts acylation reaction by mixing chlorobenzene with propionyl chloride in the presence...
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  • Thumbnail for Catalysis
    Catalysis (redirect from Catalytic reaction)
    prohibitively expensive on a large scale. Examples include the Heck reaction, and FriedelCrafts reactions. Because most bioactive compounds are chiral, many pharmaceuticals...
    46 KB (5,235 words) - 20:06, 2 November 2024
  • Thumbnail for Ketone
    Ketone (section Reactions)
    reagents. aryl ketones can be prepared in the FriedelCrafts acylation, the related Houben–Hoesch reaction, and the Fries rearrangement. Ozonolysis, and...
    24 KB (2,895 words) - 09:31, 2 November 2024
  • Thumbnail for Michler's ketone
    ketone is prepared today as it was originally by Michler using the Friedel-Crafts acylation of dimethylaniline (C6H5NMe2) using phosgene (COCl2) or equivalent...
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  • 603 (2004); Vol. 79, p.93 (2002).Link Diastereoselective Friedel-Crafts Cyclization Reactions to 2-Substituted 1-Phenyl-1,2,3,4-tetrahydronaphthalenes...
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  • technical science for his study of “Velocity measurements in the reaction of Friedel and Crafts” [translated from Dutch]. He subsequently worked as an assistant...
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  • Acetylation (category Organic reactions)
    acetylations. Acetylations are often used in making C-acetyl bonds in Friedel-Crafts reactions. Carbanions and their equivalents are susceptible to acetylations...
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  • Thumbnail for (Mesitylene)molybdenum tricarbonyl
    ligand is indicated by its ability to undergo Friedel-Crafts reactions, e.g. with acetyl chloride. Such reactions are slower on the tricarbonyl(mesitylene)molybdenum...
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  • Ferrocene (category CS1 German-language sources (de))
    undergoes substitution reactions rather than addition reactions on the cyclopentadienyl ligands. For example, Friedel-Crafts acylation of ferrocene with...
    53 KB (5,194 words) - 17:00, 2 November 2024