The Friedel–Crafts reactions are a set of reactions developed by Charles Friedel and James Crafts in 1877 to attach substituents to an aromatic ring....
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alkylation and acylation reactions with Charles Friedel in 1876. James Crafts, the son of Royal Altamont Crafts and Marianne Mason (daughter of Senator Jeremiah...
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and mineralogy at the Sorbonne. Friedel developed the Friedel-Crafts alkylation and acylation reactions with James Crafts in 1877, and attempted to make...
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Electrophilic aromatic substitution (redirect from Tscherniac–Einhorn reaction)
sulfonation, alkylation Friedel–Crafts reaction and acylation Friedel–Crafts reaction. The most widely practised example of this reaction is the ethylation...
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Friedel-Crafts reaction Friedel family, a rich lineage of French scientists: Charles Friedel (1832–1899), French chemist known for the Friedel-Crafts...
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attack arenes. Acylium ions are intermediates in several reactions, such as the Friedel-Crafts acylation of arenes by acetyl chloride in the presence of...
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Lewis acid catalysis (category Chemical reactions)
reactions involving carbon–carbon or carbon–heteroatom bond formation can be catalyzed by Lewis acids. Examples include the Friedel-Crafts reaction,...
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for the German chemist Ludwig Gattermann and is similar to the Friedel–Crafts reaction. Modifications have shown that it is possible to use sodium cyanide...
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Leaving group (category Reaction mechanisms)
in the Friedel-Crafts reaction. Here, a strong Lewis acid is required to generate either a carbocation from an alkyl halide in the Friedel-Crafts alkylation...
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The Zone of Interest (film) (category CS1 German-language sources (de))
home in the "Zone of Interest" next to the concentration camp. Christian Friedel stars as Rudolf Höss alongside Sandra Hüller as Hedwig Höss. Development...
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1-Tetralone (category CS1 German-language sources (de))
3-Benzoylpropanoic acid itself can be obtained by a Haworth reaction (a variant of the Friedel-Crafts reaction) from benzene and succinic anhydride. The intramolecular...
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Alkylbenzene (section Reactions)
extensive biodegradable yield over BAB-based sulfonates in the 1960s. Friedel-Crafts alkylation: alkylbenzenes can be synthesized from olefins or alkyl halides...
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the Friedel–Crafts reaction Georges Friedel (1865–1933), here above described, French crystallographer and mineralogist; son of Charles Edmond Friedel (1895–1972)...
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Blanc chloromethylation (redirect from Blanc chloromethylation reaction)
moderately and strongly deactivated substrates that are inert to Friedel-Crafts reactions like acetophenone, nitrobenzene and p-chloronitrobenzene do show...
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1914 via the reaction of the methyl Grignard reagent on 2-furonitrile. Modern industrial synthesis generally involves the Friedel–Crafts acylation of...
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Frankland–Duppa reaction Fráter–Seebach alkylation Free radical halogenation Freund reaction Friedel–Crafts acylation Friedel–Crafts alkylation Friedländer...
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Tin(IV) chloride (category CS1 German-language sources (de))
dibutyltin dilaurate) and polymer stabilizers. SnCl4 is used in Friedel–Crafts reactions as a Lewis acid catalyst. For example, the acetylation of thiophene...
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not tennessine. Reaction sequence: organic reduction of ethyl benzoylacetate by sodium borohydride to a diol, followed by Friedel-Crafts alkylation with...
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Hydroquinone (section Reactions)
is highly susceptible to ring substitution by Friedel–Crafts reactions such as alkylation. This reaction is exploited en route to popular antioxidants...
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Oxalyl chloride (section Reactions)
chloride to give the corresponding acyl chloride in a process known as a Friedel-Crafts acylation. The resulting acyl chloride can be hydrolysed to form the...
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Diphenyl ether (category CS1 German-language sources (de))
reactions. The compound undergoes reactions typical of other phenyl rings, including hydroxylation, nitration, halogenation, sulfonation, and Friedel–Crafts...
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controlled, this precursor can be prepared by a standard Friedel-Crafts acylation reaction by mixing chlorobenzene with propionyl chloride in the presence...
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Catalysis (redirect from Catalytic reaction)
prohibitively expensive on a large scale. Examples include the Heck reaction, and Friedel–Crafts reactions. Because most bioactive compounds are chiral, many pharmaceuticals...
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ketone is prepared today as it was originally by Michler using the Friedel-Crafts acylation of dimethylaniline (C6H5NMe2) using phosgene (COCl2) or equivalent...
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Stereoselectivity (redirect from Reaction selectivity)
603 (2004); Vol. 79, p.93 (2002).Link Diastereoselective Friedel-Crafts Cyclization Reactions to 2-Substituted 1-Phenyl-1,2,3,4-tetrahydronaphthalenes...
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technical science for his study of “Velocity measurements in the reaction of Friedel and Crafts” [translated from Dutch]. He subsequently worked as an assistant...
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Acetylation (category Organic reactions)
acetylations. Acetylations are often used in making C-acetyl bonds in Friedel-Crafts reactions. Carbanions and their equivalents are susceptible to acetylations...
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(Mesitylene)molybdenum tricarbonyl (section Reactions)
ligand is indicated by its ability to undergo Friedel-Crafts reactions, e.g. with acetyl chloride. Such reactions are slower on the tricarbonyl(mesitylene)molybdenum...
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Ferrocene (category CS1 German-language sources (de))
undergoes substitution reactions rather than addition reactions on the cyclopentadienyl ligands. For example, Friedel-Crafts acylation of ferrocene with...
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