DNA repair protein RAD50, also known as RAD50, is a protein that in humans is encoded by the RAD50 gene. The protein encoded by this gene is highly similar...

Rad50 may refer to: RADIX-50, a character encoding scheme in computing RAD50 (gene), in biology, encodes a DNA repair protein involved in DNA double-strand...

protein complex consisting of Mre11, Rad50, and Xrs2. It is a budding yeast homolog of the mammalian Mre11-Rad50-Nbs1 (MRN) DNA damage repair complex...

activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends...

complex (MRX complex in yeast) is a protein complex consisting of Mre11, Rad50 and Nbs1 (also known as Nibrin in humans and as Xrs2 in yeast). In eukaryotes...

RADIX 50 or RAD50 (also referred to as RADIX50, RADIX-50 or RAD-50), is an uppercase-only character encoding created by Digital Equipment Corporation...

northern Germany Spo11, a protein used in a complex along with Mre11 and Rad50 during meiotic recombination SPOC (disambiguation) This disambiguation page...

interacts with the MRE11/RAD50/NBS1 (MRN) complex. Other syndromes with clinical features similar to Nijmegen Breakage Syndrome include RAD50 deficiency and Cernunnos/NHEJ...

identified in the Acanthamoeba genome. These genes included Spo11, Mre11, Rad50, Rad51, Rad52, Mnd1, Dmc1, Msh and Mlh. This finding suggests that the ‘'Acanthamoeba'’...

proteins, which participate in the following steps: In yeast, the Mre11-Rad50-Xrs2 (MRX) complex is recruited to DSBs early and is thought to promote...

Vrielynck N, Holá M, Angelis KJ, Cuming AC, Nogué F (April 2012). "MRE11 and RAD50, but not NBS1, are essential for gene targeting in the moss Physcomitrella...

RAD50-interacting protein 1 is a protein that in humans is encoded by the RINT1 gene. RINT1 has been shown to interact with Rad50 and ZW10. GRCh38: Ensembl...

ovarian cancer are BRIP1, MSH6, RAD51C and RAD51D. CDH1, CHEK2, PALB2 and RAD50 have also been associated with ovarian cancer. Several rare genetic disorders...

in the cell as a complex, along with a third protein expressed by the hRad50 gene. This complex, known as the MRN complex, plays an important role in...

MRE11A MSH2 MSH3 MSH6 Myc NBN NMI NPM1 NCOA2 NUFIP1 P53 PALB2 POLR2A PPP1CA Rad50 RAD51 RBBP4 RBBP7 RBBP8 RELA RB1 RBL1 RBL2 RPL31 SMARCA4 SMARCB1 STAT1 TOPBP1...

employed in meiosis of sexual eukaryotes. These genes included Spo11, Mre11, Rad50, Rad51, Rad52, Mnd1, Dmc1, Msh, and Mlh. This finding suggests that Acanthamoeba...

"MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex". Nature Communications. 6: 7744. Bibcode:2015NatCo...6.7744L...

the breaks are associated most immediately with DNA repair enzymes MRE11, RAD50 and ATR. Genomes can be analyzed systematically to identify regulatory regions...

It is a 754 amino acid protein identified as a member of the NBS1/hMre11/RAD50(N/M/R, more commonly referred to as MRN) double strand DNA break repair...

HR-related genes. Defects in the NHEJ mechanism are related to the mutations in hRAD50 and/or hMRE11 genes in mismatch repair deficient tumors. DNA damage & repair...

many other processes, are also found in all domains of life. Rad54, Mre11, Rad50, and a number of other proteins are also found in both archaea and eukaryotes...

this mutation is viable is due to the double-strand break repair genes RAD50, RAD51 and RAD52. The RAD27/FEN1 creates nicks between adjacent Okazaki...

before repair can take place. One such nuclease is Mre11 complexed with Rad50. Mutations of Mre11 can precipitate ataxia-telangiectasia-like disorder...

one subunit and the LSGGQ motif of the other. This was first observed in Rad50 and reported in structures of MJ0796, the NBD subunit of the LolD transporter...

employed in meiosis of sexual eukaryotes. These genes included Spo11, Mre11, Rad50, Rad51, Rad52, Mnd1, Dmc1, Msh and Mlh. This finding suggests that Acanthamoeba...

compaction and reorganization of the nucleoid. Compaction depends on the Mre11-Rad50 protein complex that catalyzes an early step in homologous recombinational...

damage response to double strand breaks. The MRN complex (composed of Mre11, Rad50, and Nbs1) form immediately at the site of double strand break. This MRN...

2008). "A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex". Nature Chemical Biology. 4 (2): 119–25. doi:10.1038/nchembio...

involved with the repair pathway, the MRN complex (which consists of Mre11, Rad50 and NBS1) is attracted to the broken DNA ends and other MRN complexes to...

PMC 1149427. PMID 15849264. Le, S; Moore, JK; Haber, JE; Greider, CW (May 1999). "RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in...