Members of the signal transducer and activator of transcription (STAT) protein family are intracellular transcription factors that mediate many aspects...
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attributes of an inode Stat (TV series), an American sitcom that aired in 1991 Stat (website), a health-oriented news website STAT protein, a signal transducer...
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The JAK-STAT signaling pathway is a chain of interactions between proteins in a cell, and is involved in processes such as immunity, cell division, cell...
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STAT inhibitors are drugs which target signal transducer and activator of transcription (STAT) proteins, a family of cytoplasmic induction factors. Inhibitors...
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STAT1 (redirect from Germline STAT 1 Mutation)
humans is encoded by the STAT1 gene. It is a member of the STAT protein family. All STAT molecules are phosphorylated by receptor associated kinases...
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Horsch K, Daly JM, Hynes NE (June 1999). "ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases". The Journal of...
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Protein inhibitor of activated STAT (PIAS), also known as E3 SUMO-protein ligase PIAS, is a protein that regulates transcription in mammals. PIAS proteins...
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is Janus kinase (JAK), many of whose effects are mediated by STAT proteins. (See JAK-STAT pathway.) Some kinases have dual-specificity kinase activities...
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STAT2 (category Proteins)
transcription 2 is a protein that in humans is encoded by the STAT2 gene. It is a member of the STAT protein family. This protein is critical to the biological...
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(SOCS3 or SOCS-3) is a protein that in humans is encoded by the SOCS3 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known...
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Paracrine signaling (section JAK-STAT pathway)
attract STAT proteins. The STAT proteins dimerize and enter the nucleus to act as transcription factors to alter gene expression. In particular, the STATs transcribe...
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SUMO-protein ligase PIAS4 is one of several protein inhibitor of activated STAT (PIAS) proteins. It is also known as protein inhibitor of activated STAT protein...
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activation of the JAK/STAT (Janus kinase/signal transducer and activator of transcription) and MAPK (mitogen activated protein kinase) cascades.[citation...
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Janus kinase (redirect from Janus protein kinase)
non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway. They were initially named "just another kinase" 1 and 2 (since they...
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Cluster of differentiation 40, CD40 is a type I transmembrane protein found on antigen-presenting cells and is required for their activation. The binding...
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Interferon gamma (section JAK-STAT pathway)
more commonly referred to as the JAK-STAT pathway. In the JAK-STAT pathway, activated JAK1 and JAK2 proteins regulate the phosphorylation of tyrosine...
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λεπτός leptos, "thin" or "light" or "small"), also known as obese protein, is a protein hormone predominantly made by adipocytes (cells of adipose tissue)...
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Interleukin 6 (section Protein superfamily)
acute phase response. IL-6 is responsible for stimulating acute phase protein synthesis, as well as the production of neutrophils in the bone marrow...
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Philadelphia chromosome (redirect from Bcr-abl fusion protein)
region BCR gene of chromosome 22, coding for a hybrid protein: a tyrosine kinase signaling protein that is "always on", causing the cell to divide uncontrollably...
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STAT6 (category Proteins)
the Signal Transducer and Activator of Transcription (STAT) family of proteins. The proteins of STAT family transmit signals from a receptor complex to the...
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IFNA2 (section Protein family)
members of the family Signal Transducer and Activator of Transcription (STAT protein); phosphorylated STAT1 and STAT2 bind IRF9 forming a complex named "IFN-Stimulated...
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G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved...
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signal proteins of the signal transducer and activator of transcription (STAT) protein family – which include transcription factors for target genes that serve...
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Poly(ADP-ribose) polymerase family member 14 is a protein that, in humans, is encoded by the PARP14 gene. Poly(ADP-ribosyl)ation is an immediate DNA damage-dependent...
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histamine secretion positive regulation of tyrosine phosphorylation of STAT protein cellular response to granulocyte macrophage colony-stimulating factor...
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Insulin-like growth factor 1 (category Aging-related proteins)
was termed "nonsuppressible insulin-like activity" (NSILA). IGF-1 is a protein that in humans is encoded by the IGF1 gene. IGF-1 consists of 70 amino...
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encodes for the 770 amino acid protein, STAT3. STAT3 is part of a family of proteins known as the STAT protein. These proteins play an essential role in chemical...
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