• Thumbnail for Sirolimus
    in 1999. Hyftor (sirolimus gel) was approved for topical treatment of facial angiofibroma in the European Union in May 2023. Sirolimus is indicated for...
    70 KB (7,051 words) - 03:41, 9 November 2024
  • Thumbnail for Lymphatic malformations
    lymphatics feeding into the lymphocele." Sirolimus is used to treat lymphangioma. Treatment with sirolimus can decrease pain and the fullness of venous...
    23 KB (2,582 words) - 01:20, 22 September 2024
  • Thumbnail for Everolimus
    needed] It is the 40-O-(2-hydroxyethyl) derivative of sirolimus and works similarly to sirolimus as an inhibitor of mammalian target of rapamycin (mTOR)...
    27 KB (2,534 words) - 20:49, 4 October 2024
  • Thumbnail for Immunosuppressive drug
    Everolimus is an analog of sirolimus and also is an mTOR inhibitor. Zotarolimus is a semi-synthetic derivative of sirolimus used in drug-eluting stents...
    29 KB (3,378 words) - 02:54, 25 September 2024
  • Thumbnail for MTOR inhibitors
    sites for mTOR and FKBP12. The bacterial natural product rapamycin or sirolimus, a cytostatic agent, has been used in combination therapy with corticosteroids...
    57 KB (6,281 words) - 12:56, 6 November 2024
  • Thumbnail for Lymphangioleiomyomatosis
    (mTORC1) led to successful use of rapamycin analog sirolimus in clinical trials and FDA approval of sirolimus for treatment of LAM. TSC1 and TSC2 form a tumor...
    100 KB (11,094 words) - 10:45, 2 November 2024
  • Thumbnail for Hives
    medications (dapsone, sulfasalazine), immunosuppressants (cyclosporin, sirolimus) or other medications like omalizumab can be used. These options are explained...
    50 KB (5,769 words) - 14:49, 25 October 2024
  • provide a "scaffold" to open the artery. An anti-rejection-type medication, sirolimus, helps to limit the overgrowth of normal cells while the artery heals...
    2 KB (178 words) - 20:25, 12 March 2024
  • Thumbnail for Methylprednisolone
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    57 KB (5,143 words) - 05:47, 15 October 2024
  • Thumbnail for Neurofibroma
    Sirolimus, a compound that inhibits mTOR signalling, is being studied to treat plexiform neurofibromas. The combination of erlotinib with sirolimus was...
    30 KB (3,257 words) - 16:53, 28 October 2024
  • Thumbnail for Tacrolimus
    hypomagnesemia, hyperglycemia, diabetes mellitus, itching, lung damage (sirolimus also causes lung damage), and various neuropsychiatric problems such as...
    43 KB (4,357 words) - 08:39, 29 October 2024
  • Thumbnail for Streptomyces hygroscopicus
    hygroscopicus can be used to produce several chemical compounds or enzymes. Sirolimus (also known as rapamycin) is an antifungal and immunosuppressant that...
    5 KB (318 words) - 15:29, 28 May 2024
  • Thumbnail for Percutaneous coronary intervention
    drug-eluting stents to be utilized were the paclitaxel-eluting stent and the sirolimus-eluting stent, both of which have received approval from the U.S. Food...
    48 KB (5,360 words) - 06:42, 22 September 2024
  • Thumbnail for Flucloxacillin
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    24 KB (2,105 words) - 06:45, 2 October 2024
  • cyclophosphamide, ciclosporin, tacrolimus, everolimus, thymoglobulin and sirolimus. Newer, so-called "biologic drugs" or monoclonal antibodies, are also...
    25 KB (2,838 words) - 02:41, 5 October 2024
  • Thumbnail for Rifampicin
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    47 KB (4,718 words) - 05:12, 30 October 2024
  • Thumbnail for Fentanyl
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    174 KB (16,182 words) - 18:46, 5 November 2024
  • Thumbnail for Drug-eluting stent
    and Drug Administration (FDA) were sirolimus-eluting stents (SES), which release a natural product called sirolimus, an immunosuppressant drug. SES were...
    136 KB (14,041 words) - 10:43, 6 November 2024
  • Thumbnail for Leukopenia
    after, in particular, high-dose therapy. Immunosuppressive drugs, such as sirolimus, mycophenolate mofetil, tacrolimus, ciclosporin, leflunomide and TNF inhibitors...
    9 KB (810 words) - 17:18, 30 September 2024
  • usually caused by the prolonged use of T cell suppressant drugs, such as sirolimus, tacrolimus, or ciclosporin. The Epstein-Barr virus, which infects >90%...
    8 KB (776 words) - 14:33, 15 August 2024
  • Thumbnail for Nicotine
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    136 KB (14,214 words) - 18:53, 6 November 2024
  • antibody coating of the Genous Stent with antiproliferative sirolimus elution. The sirolimus drug reduces the risk of stent restenosis through inhibiting...
    14 KB (1,348 words) - 01:13, 16 March 2024
  • Thumbnail for Graft-versus-host disease
    substances that have been studied for GvHD treatment include, for example: sirolimus, pentostatin, etanercept, and alemtuzumab. In August 2017, the US FDA...
    39 KB (4,442 words) - 15:41, 17 October 2024
  • 2018). "Targeted therapy with a localised abluminal groove, low-dose sirolimus-eluting, biodegradable polymer coronary stent (TARGET All Comers): a multicentre...
    12 KB (923 words) - 06:22, 2 September 2024
  • Thumbnail for Scleroderma
    cyclophosphamide, mycophenolate, intravenous immunoglobulin, rituximab, sirolimus, alefacept, and the tyrosine kinase inhibitors, imatinib, nilotinib, and...
    38 KB (3,293 words) - 18:29, 29 August 2024
  • Thumbnail for Rifaximin
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    25 KB (2,335 words) - 14:04, 2 November 2024
  • Thumbnail for Fenbendazole
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    9 KB (673 words) - 18:57, 5 November 2024
  • Thumbnail for Tetracycline
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    29 KB (2,627 words) - 15:59, 29 October 2024
  • Thumbnail for Ritonavir
    disopyramide, immunosuppressants such as tacrolimus, voclosporin and sirolimus, neuroleptics like clozapine, lurasidone and pimozide, as well as some...
    42 KB (3,598 words) - 01:06, 23 October 2024
  • hypogammaglobulinemia (transient) requiring IVIgG replacement.[citation needed] Sirolimus (rapamycin, rapamune) which is a mTOR (mammalian target of rapamycin)...
    26 KB (2,502 words) - 02:54, 15 July 2024