• Thumbnail for Toll-like receptor 3
    Toll-like receptor 3 (TLR3) also known as CD283 (cluster of differentiation 283) is a protein that in humans is encoded by the TLR3 gene. TLR3 is a member...
    9 KB (1,027 words) - 06:24, 13 September 2024
  • Thumbnail for Toll-like receptor
    Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system. They are single-spanning receptors usually expressed...
    61 KB (6,763 words) - 16:03, 3 September 2024
  • Thumbnail for Toll-like receptor 4
    Toll-like receptor 4 (TLR4), also designated as CD284 (cluster of differentiation 284), is a key activator of the innate immune response and plays a central...
    75 KB (9,082 words) - 22:17, 25 September 2024
  • Thumbnail for Toll-like receptor 2
    Toll-like receptor 2 also known as TLR2 is a protein that in humans is encoded by the TLR2 gene. TLR2 has also been designated as CD282 (cluster of differentiation...
    22 KB (2,409 words) - 10:20, 12 August 2024
  • Thumbnail for Toll-like receptor 8
    Toll-like receptor 8 is a protein that in humans is encoded by the TLR8 gene. TLR8 has also been designated as CD288 (cluster of differentiation 288)....
    9 KB (1,091 words) - 21:43, 4 April 2024
  • Thumbnail for Toll-like receptor 7
    Toll-like receptor 7, also known as TLR7, is a protein that in humans is encoded by the TLR7 gene. Orthologs are found in mammals and birds. It is a member...
    13 KB (1,424 words) - 04:29, 22 July 2024
  • Thumbnail for Toll-like receptor 9
    Toll-like receptor 9 is a protein that in humans is encoded by the TLR9 gene. TLR9 has also been designated as CD289 (cluster of differentiation 289)....
    21 KB (2,507 words) - 06:13, 13 September 2024
  • Thumbnail for Toll-like receptor 5
    Toll-like receptor 5, also known as TLR5, is a protein which in humans is encoded by the TLR5 gene. It is a member of the toll-like receptor (TLR) family...
    19 KB (2,255 words) - 05:11, 7 May 2024
  • Thumbnail for Toll-like receptor 1
    Toll-like receptor 1 (TLR1) is a member of Toll-like receptors (TLRs), which is a family of pattern recognition receptors (PRRs) that form the cornerstone...
    12 KB (1,377 words) - 21:42, 4 April 2024
  • Thumbnail for Toll-like receptor 6
    Toll-like receptor 6 is a protein that in humans is encoded by the TLR6 gene. TLR6 is a transmembrane protein, member of toll-like receptor family, which...
    8 KB (1,073 words) - 21:43, 4 April 2024
  • Thumbnail for Toll-like receptor 11
    pseudogene. TLR11 belongs to the toll-like receptor (TLR) family and the interleukin-1 receptor/toll-like receptor superfamily. In mice, TLR11 has been...
    11 KB (1,460 words) - 08:55, 8 November 2023
  • Thumbnail for Toll-like receptor 10
    Toll-like receptor 10 is a protein that in humans is encoded by the TLR10 gene. TLR10 has also been designated as CD290 (cluster of differentiation 290)...
    6 KB (833 words) - 19:32, 7 September 2023
  • Thumbnail for MYD88
    MYD88 (category Genes on human chromosome 3)
    activation through Toll-like receptors (TLRs), which belong to large group of pattern recognition receptors (PRR). In general, these receptors sense common...
    20 KB (2,250 words) - 15:55, 30 July 2024
  • Thumbnail for Polyinosinic:polycytidylic acid
    to simulate viral infections. Poly I:C is known to interact with toll-like receptor 3 (TLR3), which is expressed at the endosomal membrane of B-cells,...
    5 KB (396 words) - 08:34, 8 March 2024
  • Thumbnail for NOD-like receptor
    recognition receptors (PRRs), and play key roles in the regulation of innate immune response. NLRs can cooperate with toll-like receptors (TLRs) and regulate...
    14 KB (1,532 words) - 23:00, 21 November 2023
  • include toll-like receptors (TLRs) and C-type lectin receptors (CLRs). Cytoplasmic PRRs include NOD-like receptors (NLRs) and RIG-I-like receptors (RLRs)...
    43 KB (5,173 words) - 21:02, 10 August 2024
  • Thumbnail for Protease-activated receptor 2
    Protease activated receptor 2 (PAR2) also known as coagulation factor II (thrombin) receptor-like 1 (F2RL1) or G-protein coupled receptor 11 (GPR11) is a...
    24 KB (2,715 words) - 22:33, 27 March 2024
  • Thumbnail for Toll-interleukin receptor
    protein-protein interactions between the toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins...
    8 KB (839 words) - 21:44, 4 April 2024
  • Thumbnail for Dirt
    LV; Schmidt, RR (22 November 2009), "Commensal bacteria regulate Toll-like receptor 3–dependent inflammation after skin injury", Nature Medicine, 15 (12):...
    9 KB (929 words) - 15:30, 14 August 2024
  • polylysine. It is under trial for use in cancer. Poly I:C is a ligand for toll like receptor-3, which usually triggers on the structurally similar double-stranded...
    3 KB (122 words) - 08:22, 23 September 2024
  • Novakofski JE, et al. (February 2023). "The Impact of Variation in the Toll-like Receptor 3 Gene on Epizootic Hemorrhagic Disease in Illinois Wild White-Tailed...
    15 KB (1,941 words) - 23:53, 8 January 2024
  • Thumbnail for TIRAP
    molecule associated with toll-like receptors. The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify...
    1 KB (179 words) - 19:07, 9 June 2023
  • "Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3". Nature. 413 (6857): 732–738. Bibcode:2001Natur.413..732A. doi:10...
    34 KB (4,151 words) - 09:53, 12 September 2024
  • rarediseases.info.nih.gov. Retrieved 2023-03-05. "Entry - *603029 - TOLL-LIKE RECEPTOR 3 - OMIM". omim.org. Retrieved 2023-03-05. "Entry - #614212 - ENCEPHALOPATHY...
    11 KB (857 words) - 21:45, 30 May 2024
  • Thumbnail for Yellow fever
    "Sensing of viral infection and activation of innate immunity by toll-like receptor 3". Clinical Microbiology Reviews. 21 (1): 13–25. doi:10.1128/CMR.00022-07...
    111 KB (12,218 words) - 02:43, 27 September 2024
  • Thumbnail for Mollaret's meningitis
    Ahmad-Nejad; Michael Neumaier; Michael G. Hennerici; Marc Fatar (2010). "Toll-Like Receptor 3 Immune Deficiency May Be Causative for HSV-2-Associated Mollaret...
    14 KB (1,604 words) - 09:18, 14 September 2024
  • Thumbnail for HAVCR2
    HAVCR2 (redirect from TIM-3)
    endosomal Toll-like receptors (TLRs).  HMGB1 binds to HAVCRS2/TIM3 on dendritic cells but its binding site has not been determined. TIM-3 receptor prevents...
    25 KB (2,940 words) - 07:05, 3 September 2024
  • Thumbnail for CU-CPT4a
    CU-CPT4a (category Receptor antagonists)
    CU-CPT4a is a drug which acts as a selective antagonist of Toll-like receptor 3 (TLR3), with an IC50 of 3.44 μM. It is used for research into the function of...
    2 KB (164 words) - 11:36, 31 October 2023
  • RIG-I-like receptors (retinoic acid-inducible gene-I-like receptors, RLRs) are a type of intracellular pattern recognition receptor involved in the recognition...
    25 KB (3,011 words) - 17:07, 24 May 2024
  • Thumbnail for Katalin Karikó
    Drew Weissman (16 January 2004). "mRNA is an endogenous ligand for Toll-like receptor 3". Journal of Biological Chemistry. 279 (13): 12542–12550. doi:10...
    43 KB (4,593 words) - 00:29, 24 September 2024