• Trace amine-associated receptors (TAARs), sometimes referred to as trace amine receptors (TAs or TARs), are a class of G protein-coupled receptors that...
    32 KB (2,036 words) - 11:13, 25 February 2024
  • Thumbnail for TAAR1
    Trace amine-associated receptor 1 (TAAR1) is a trace amine-associated receptor (TAAR) protein that in humans is encoded by the TAAR1 gene. TAAR1 is an...
    60 KB (6,935 words) - 21:06, 17 December 2024
  • Thumbnail for Trace amine
    Trace amines are an endogenous group of trace amine-associated receptor 1 (TAAR1) agonists – and hence, monoaminergic neuromodulators – that are structurally...
    20 KB (2,302 words) - 02:01, 24 November 2024
  • Thumbnail for RO5203648
    RO5203648 (category Amines)
    RO5203648 is a trace amine-associated receptor 1 (TAAR1) partial agonist. It is a potent and highly selective partial agonist of both rodent and primate...
    22 KB (2,054 words) - 11:23, 22 December 2024
  • Thumbnail for TAAR2
    Trace amine-associated receptor 2 (TAAR2), formerly known as G protein-coupled receptor 58 (GPR58), is a protein that in humans is encoded by the TAAR2...
    9 KB (946 words) - 19:05, 15 August 2024
  • W (October 2016). "The emerging roles of human trace amines and human trace amine-associated receptors (hTAARs) in central nervous system". Biomed. Pharmacother...
    8 KB (1,436 words) - 17:54, 28 December 2023
  • Thumbnail for Phenethylamine
    phenethylamine regulates monoamine neurotransmission by binding to trace amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2...
    54 KB (5,178 words) - 18:43, 13 December 2024
  • Thumbnail for Tryptamine
    Tryptamine (category Trace amines)
    others. Tryptamine has been shown to activate serotonin receptors and trace amine-associated receptors expressed in the mammalian brain, and regulates the...
    50 KB (4,029 words) - 22:49, 23 December 2024
  • Thumbnail for RO5263397
    RO5263397 (category Amines)
    is a trace amine-associated receptor 1 (TAAR1) partial agonist which is used in scientific research. RO5263397 is a trace amine-associated receptor 1 (TAAR1)...
    6 KB (406 words) - 11:29, 19 December 2024
  • Thumbnail for Trimethylamine
    TAAR5, a trace amine-associated receptor that is expressed in the olfactory epithelium and functions as an olfactory receptor for tertiary amines. One or...
    17 KB (1,630 words) - 12:42, 26 November 2024
  • Thumbnail for TAAR5
    Trace amine-associated receptor 5 is a protein that in humans is encoded by the TAAR5 gene. In vertebrates, TAAR5 is expressed in the olfactory epithelium...
    8 KB (928 words) - 07:45, 8 October 2024
  • Thumbnail for Adderall
    which results in part from their interactions with human trace amine-associated receptor 1 (hTAAR1) and vesicular monoamine transporter 2 (VMAT2) in...
    63 KB (22,430 words) - 04:07, 24 December 2024
  • Thumbnail for EPPTB
    potent and selective antagonist or inverse agonist of the trace amine-associated receptor 1 (TAAR1). The drug was the first selective antagonist developed...
    37 KB (4,068 words) - 11:47, 19 December 2024
  • Autoreceptor (category Receptors)
    "Modulation of Monoamine Transporters by Common Biogenic Amines via Trace Amine-Associated Receptor 1 and Monoamine Autoreceptors in Human Embryonic Kidney...
    8 KB (807 words) - 09:55, 11 December 2024
  • Thumbnail for TAAR8
    Trace amine-associated receptor 8 is a protein that in humans is encoded by the TAAR8 gene. In humans, TAAR8 is the only trace amine-associated receptor...
    3 KB (391 words) - 02:23, 29 November 2023
  • Thumbnail for Olfactory receptor
    “odor space” of a population of native aldehyde receptors. Phantosmia Receptor Trace amine-associated receptor Odorant Pseudogenes Gene family Gaillard I,...
    36 KB (4,353 words) - 15:38, 20 September 2024
  • RG-7351 is a trace amine-associated receptor 1 (TAAR1) partial agonist that is or was under development for the treatment of major depressive disorder...
    3 KB (183 words) - 11:31, 19 December 2024
  • Thumbnail for RO5166017
    RO5166017 (category Amines)
    Roche which acts as a potent and selective agonist for the trace amine-associated receptor 1 (TAAR1), with no significant activity at other targets. It...
    8 KB (697 words) - 11:35, 19 December 2024
  • Thumbnail for Amphetamine
    W (October 2016). "The emerging roles of human trace amines and human trace amine-associated receptors (hTAARs) in central nervous system". Biomedicine...
    279 KB (29,447 words) - 12:23, 22 December 2024
  • Thumbnail for Dextroamphetamine
    serotonin, norepinephrine and dopamine transporters) either via trace amine-associated receptor 1 (TAAR1) or in a TAAR1 independent fashion when there are...
    64 KB (21,532 words) - 09:38, 21 December 2024
  • Thumbnail for Monoamine neurotransmitter
    W (October 2016). "The emerging roles of human trace amines and human trace amine-associated receptors (hTAARs) in central nervous system". Biomed. Pharmacother...
    7 KB (1,409 words) - 21:17, 11 March 2024
  • RG-7410 is a trace amine-associated receptor 1 (TAAR1) agonist which was under development for the treatment of schizophrenia but was never marketed....
    3 KB (136 words) - 02:23, 23 October 2024
  • Thumbnail for Substituted cathinone
    substituted cathinones do not act as agonists of the human trace amine-associated receptor 1 (TAAR1). This may potentiate their stimulating and addictive...
    56 KB (2,453 words) - 06:04, 8 December 2024
  • Thumbnail for Levmetamfetamine
    norepinephrine-releasing activity, levmetamfetamine is also an agonist of the trace amine-associated receptor 1 (TAAR1). Levmetamfetamine has also been found to act as a...
    51 KB (5,047 words) - 17:31, 11 December 2024
  • Thumbnail for Tyramine
    Tyramine (redirect from Tyramine receptor)
    tyramin), also known under several other names, is a naturally occurring trace amine derived from the amino acid tyrosine. Tyramine acts as a catecholamine...
    29 KB (2,685 words) - 23:57, 2 December 2024
  • Thumbnail for Methamphetamine
    identified as a potent full agonist of trace amine-associated receptor 1 (TAAR1), a G protein-coupled receptor (GPCR) that regulates brain catecholamine...
    163 KB (15,931 words) - 20:58, 22 December 2024
  • Thumbnail for Dopamine
    activity of an intracellular trace amine-associated receptor, TAAR1. TAAR1 is a high-affinity receptor for dopamine, trace amines, and certain substituted...
    139 KB (14,295 words) - 21:14, 14 December 2024
  • Thumbnail for Neurotransmitter
    serotonin pathways) throughout the brain via signaling through trace amine-associated receptor 1. A brief comparison of these systems follows: Understanding...
    99 KB (8,867 words) - 23:25, 14 December 2024
  • Thumbnail for N-Methylphenethylamine
    N-Methylphenethylamine (NMPEA) is a naturally occurring trace amine neuromodulator in humans that is derived from the trace amine, phenethylamine (PEA). It has been detected...
    10 KB (1,125 words) - 02:12, 22 April 2024
  • Thumbnail for RO5256390
    RO5256390 (category Amines)
    developed by Hoffmann-La Roche which acts as an agonist for the trace amine associated receptor 1 (TAAR1), which has been shown to block compulsive and binge-like...
    4 KB (295 words) - 11:38, 19 December 2024