Tumor-associated endothelial cells or tumor endothelial cells (TECs) refers to cells lining the tumor-associated blood vessels that control the passage...
20 KB (2,331 words) - 22:03, 23 July 2022
hallmarks of cancer. In later stages of tumor progression endothelial cells can differentiate into carcinoma associated fibroblasts, which furthers metastasis...
65 KB (6,977 words) - 08:53, 6 September 2024
which protects the tumor from the immune system, is the result of exposure to angiogenic growth factors. Next to endothelial cell anergy, there are more...
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differentiation of other tumor adjacent cells such as epithelial or endothelial cells, adipocytes, pericytes and smooth muscle cells. Adipocytes, especially...
31 KB (3,599 words) - 19:59, 30 June 2024
inflammation by binding to its target receptors on other cells. It is a member of the tumor necrosis factor superfamily, a family of transmembrane proteins...
68 KB (8,811 words) - 19:08, 3 October 2024
carcinoid tumor, salivary gland carcinoma, and unclassified carcinoma. All types can occur in unusual histologic variants and as mixed cell-type combinations...
51 KB (5,333 words) - 22:13, 7 September 2024
freely secreted or cell-associated isoforms, have been characterized. VEGF-A shows prominent activity with vascular endothelial cells, primarily through...
24 KB (3,053 words) - 21:43, 17 August 2024
Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells that...
40 KB (4,578 words) - 12:30, 10 September 2024
Tumor-associated macrophages (TAMs) are a class of immune cells present in high numbers in the microenvironment of solid tumors. They are heavily involved...
22 KB (2,507 words) - 23:16, 25 July 2024
Metastasis (redirect from Metastatic tumor)
the blood vessel cells (endothelial cells), immune cells or stromal cells. The growth of a new network of blood vessels, called tumor angiogenesis, is...
41 KB (5,006 words) - 15:19, 25 September 2024
Angiogenesis (redirect from Tip cells)
tumor. Evidence now suggests the blood vessel in a given solid tumor may, in fact, be mosaic vessels, composed of endothelial cells and tumor cells....
50 KB (5,887 words) - 15:45, 22 September 2024
vascular tumor to affect babies, accounting for 90% of hemangiomas. They are characterised by the abnormal proliferation of endothelial cells and of deviant...
13 KB (1,300 words) - 14:29, 21 September 2024
Microvesicle (redirect from Endothelial microparticle)
demonstrated that tumor-associated microvesicles release proangiogenic factors that promote endothelial cell proliferation, angiogenesis, and tumor growth. Microvesicles...
54 KB (6,074 words) - 11:15, 28 July 2024
A sarcoma is a malignant tumor, a type of cancer that arises from cells of mesenchymal (connective tissue) origin. Connective tissue is a broad term that...
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Furthermore, these cells secrete an abundance of factors that help regulate tumor development. Potential targets for tumor-associated stromal cell recruitment...
21 KB (2,735 words) - 16:58, 28 November 2023
Promotes Macropinocytosis of Kaposi's Sarcoma-Associated Herpesvirus in Human Dermal Microvascular Endothelial Cells". Journal of Virology. 90 (8): 3860–3872...
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type of benign liver tumor, found in 3%–10% of people. They are made up of blood clusters that are surrounded by endothelial cells. These hemangiomas get...
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to stem cells, capable of differentiating to mimic the function of endothelial cells and form vasculature-like structures. The ability of tumors to develop...
36 KB (3,578 words) - 03:14, 2 September 2024
endothelial cell formation and migration, endothelial tube morphogenesis, and down-regulation of genes expressed in endothelial cells. During tumor growth...
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cell (Madin-Darby Bovine Kidney) DF-1cell (chicken fibroblast) Mouse cell lines MC3T3 (embryonic calvarium) Rat tumor cell lines GH3 (pituitary tumor)...
108 KB (8,405 words) - 23:07, 14 August 2024
attack. Embryonic cord-blood cells were induced into pluripotent stem cells using plasmid DNA. Using cell surface endothelial/pericytic markers CD31 and...
92 KB (10,518 words) - 09:00, 6 September 2024
A circulating tumor cell (CTC) is a cell that has shed into the vasculature or lymphatics from a primary tumor and is carried around the body in the blood...
67 KB (8,163 words) - 17:26, 27 April 2024
Kaposi's sarcoma (redirect from AIDS-associated Kaposi sarcoma)
of vascular endothelial growth factor receptor-3 and podoplanin suggests a lymphatic endothelial cell origin of Kaposi's sarcoma tumor cells". Laboratory...
37 KB (4,058 words) - 00:51, 10 August 2024
Neurofibroma (redirect from Solitary nerve sheath tumor)
perineurial cells, endothelial cells, and mast cells. The mast cells then secrete mitogens or survival factors that alter the developing tumor microenvironment...
30 KB (3,257 words) - 22:04, 21 September 2024
stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically...
86 KB (10,355 words) - 13:54, 28 August 2024
Burkitt lymphoma (redirect from Burkitt's tumor)
histiocytes or endothelial cells). "Small non-cleaved cells" are compared to "large non-cleaved cells" of normal germinal center lymphocytes. Tumor cells possess...
38 KB (4,416 words) - 08:01, 25 August 2024
against tumors. Some cancer therapies involve the creation of artificial APCs to prime the adaptive immune system to target malignant cells. Antigen-presenting...
16 KB (2,128 words) - 09:55, 4 March 2024
Hemangioendothelioma (redirect from Dabska tumor)
Characteristic budding, hobnail-like endothelial cells visible. Treatment is varied and depends on the site and extent of tumor involvement, sites of metastasis...
14 KB (1,476 words) - 09:18, 21 September 2024
Phyllodes tumors (from Greek: phullon), are a rare type of biphasic fibroepithelial mass that form from the periductal stromal and epithelial cells of the...
22 KB (2,255 words) - 06:49, 23 March 2024
the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The...
10 KB (1,378 words) - 23:28, 27 March 2024