Mitochondrial uncoupling protein 3 is a protein that in humans is encoded by the UCP3 gene. The gene is located in chromosome (11q13.4) with an exon count of 7...
15 KB (1,928 words) - 11:46, 4 January 2024
UCPs are related to thermogenesis. Although UCP2 and UCP3 are closely related to UCP1, UCP2 and UCP3 do not affect thermoregulatory abilities of vertebrates...
17 KB (1,876 words) - 06:54, 27 April 2024
reduces production of reactive oxygen species (ROS). In contrast to UCP1 and UCP3, which are primarily expressed in adipose and smooth muscle, UCP2 is expressed...
9 KB (1,160 words) - 02:06, 19 August 2023
decade, three additional homologs of UCP1 have been identified, including UCP3, UCP4, and UCP5 (also known as BMCP1 or SLC25A14). Methods of delivering...
21 KB (2,577 words) - 22:40, 6 April 2024
"Thermogenic responses in brown fat cells are fully UCP1-dependent. UCP2 or UCP3 do not substitute for UCP1 in adrenergically or fatty scid-induced thermogenesis"...
19 KB (1,835 words) - 03:20, 24 May 2024
Ricquier D, Bouillaud F (2000). "The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP". Biochem. J. 345 (2): 161–79. doi:10.1042/0264-6021:3450161...
85 KB (9,411 words) - 15:24, 6 May 2024
(December 2002). "AMP-activated protein kinase activates transcription of the UCP3 and HKII genes in rat skeletal muscle". American Journal of Physiology. Endocrinology...
65 KB (7,147 words) - 05:41, 24 June 2024
HGNC:17781 Q969E3 17832 UCP1 HGNC:12517 P25874 17833 UCP2 HGNC:12518 P55851 17834 UCP3 HGNC:12519 P55916 17835 UEVLD HGNC:30866 Q8IX04 17836 UFC1 HGNC:26941 Q9Y3C8...
242 KB (17 words) - 23:17, 27 April 2024
Tinker L, Kuller LH, Liu S (April 2008). "Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the Women's Health Initiative Observational...
102 KB (11,469 words) - 23:37, 10 April 2024
a plausible therapeutic target for treating neurological conditions. UCP3 UCP3 is mainly expressed in adipose tissue, the lungs, and skeletal muscles;...
13 KB (1,733 words) - 16:04, 23 March 2024
(2008-12-01). "Effect of aging, caloric restriction, and uncoupling protein 3 (UCP3) on mitochondrial proton leak in mice". Experimental Gerontology. 43 (12):...
17 KB (1,624 words) - 13:03, 27 November 2023
of Cambridge, in 2000 a team gave mice a human gene that made the protein UCP3, that was found on the human Chromosome 11. The genetically-engineered mice...
10 KB (1,036 words) - 12:54, 9 April 2024
SLC25A2, SLC25A3, SLC25A4, SLC25A5, SLC25A6, UCP1(SLC25A7), UCP2(SLC25A8), UCP3(SLC25A9), SLC25A10, SLC25A11, SLC25A12, SLC25A13, SLC25A14, SLC25A15, SLC25A16...
35 KB (3,408 words) - 02:42, 30 November 2023
went on to clone and characterize mitochondrial uncoupling genes UCP2 and UCP3, in collaboration with colleagues from Prague and Beaverton, Oregon). His...
14 KB (1,583 words) - 07:51, 13 December 2023
Resistin, Senotherapy, Stearoyl-CoA desaturase-1, Uncoupling protein, UCP2, and UCP3. Notable Cambridge scientists with whom Vidal-Puig has shared paper authorship...
16 KB (1,605 words) - 21:11, 11 July 2024
C-Raf, CRTC2, CBL HDAC5, MEF2D, NRIP1, PFKFB2, PRKD1, PRKCZ, TERT, and UCP3. GRCh38: Ensembl release 89: ENSG00000134308 – Ensembl, May 2017 "Human PubMed...
16 KB (1,999 words) - 12:54, 14 August 2023
domain include: HDMCP, , MCART1, MCART2, MCART6, MTCH1, MTCH2 UCP1, UCP2, UCP3 SLC25A1, SLC25A3, SLC25A4, SLC25A5, SLC25A6, SLC25A10, SLC25A11, SLC25A12...
24 KB (2,653 words) - 03:00, 29 January 2024
Ricquier D, Bouillaud F (2000). "The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP". Biochem. J. 345 (2): 161–79. doi:10.1042/0264-6021:3450161...
7 KB (862 words) - 21:39, 27 March 2024