X-box binding protein 1, also known as XBP1, is a protein which in humans is encoded by the XBP1 gene. The XBP1 gene is located on chromosome 22 while...
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in insulin secretion and peripheral insulin resistance. Abnormalities in XBP1 lead to a heightened endoplasmic reticulum stress response and subsequently...
34 KB (3,710 words) - 16:57, 22 August 2024
transautophosphorylation. The activated domain is able to activate the transcription factor XBP1(Xbox binding protein) mRNA (the mammalian equivalent of the yeast Hac1 mRNA)...
31 KB (3,579 words) - 07:01, 26 July 2024
real-time RT-PCR to measure the rate at which XBP1 is cleaved by IRE1 when the UPR is activated. XBP1 mRNA cleavage leads to the translation of a transcription...
8 KB (951 words) - 10:49, 11 December 2023
for most of them. For example, one association is with mutations in the XBP1 gene, which is involved in the unfolded protein response pathway of the endoplasmic...
162 KB (18,417 words) - 20:04, 18 August 2024
BZIP intron RNA motif (redirect from Hac1 Xbp1 intron)
a non-canonical intron from bZIP-containing genes called HAC1 in yeast, XBP1 in Metazoa, Hxl1 or Cib1 in Basidiomycota and bZIP60 in plants. Splicing...
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are, e.g., 5-HTTLPR in the serotonin transporter gene and gene variants in XBP1. Cloninger argued that the Five Factor model does not assess domains of personality...
16 KB (1,676 words) - 09:03, 25 May 2024
ENSG00000184937 C2H2 ZF Known motif – High-throughput in vitro [1,007] BGGGGGRG XBP1 ENSG00000100219 bZIP Known motif – High-throughput in vitro [1,008] GVTGACGTGKCVHW...
374 KB (81 words) - 02:10, 23 September 2023
splicing activity, removing an intron from the X-box binding protein 1 (XBP1) mRNA, and allowing it to become translated into a functional transcription...
22 KB (2,090 words) - 02:39, 16 July 2024
deposition and premature adipocyte differentiation takes place. The expression of xbp1, master regulator of osterix gets reduced, suggesting that unfolded proteins...
23 KB (2,683 words) - 06:21, 1 August 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
39 KB (4,859 words) - 19:32, 22 August 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
87 KB (9,376 words) - 13:18, 19 August 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
37 KB (4,035 words) - 09:01, 19 August 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
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animal is an unconventional bZIP intron in animals located in the mRNA of Xbp1 orthologs. The RNA structure consists of two hairpins of similar length with...
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DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
12 KB (1,317 words) - 20:08, 28 August 2023
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
24 KB (2,820 words) - 05:34, 10 July 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
8 KB (874 words) - 23:04, 18 August 2023
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
41 KB (4,385 words) - 21:28, 21 August 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
42 KB (4,829 words) - 16:45, 1 August 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
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Griffiths-Jones S (2011). "Conserved RNA structures in the non-canonical Hac1/Xbp1 intron". RNA Biol. 8 (4): 552–556. doi:10.4161/rna.8.4.15396. PMC 3225973...
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differential expression. His work also showed that the bZIP transcription factor: XBP1 forms a hetero-dimer with c-Fos. This has turned out to be relevant to the...
58 KB (5,502 words) - 05:32, 31 May 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
26 KB (2,672 words) - 14:14, 22 July 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
57 KB (7,191 words) - 06:17, 25 July 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
75 KB (8,057 words) - 04:44, 25 July 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
16 KB (1,910 words) - 01:56, 10 August 2024
DBP DDIT3 GABPA GCN4 HLF MAF B F G K NFE 2 L1 L2 L3 NFIL3 NRL NRF 1 2 3 XBP1 (1.2) Basic helix-loop-helix (bHLH) (1.3) bHLH-ZIP AP-4 MAX MXD1 MXD3 MITF...
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the maturation of B-cells toward plasma cells (e.g. CD38, CD138, IR4/MUM1, XBP1, IL21R, and, as just indicated, PRDM1); and 6) reduced expression of genes...
25 KB (3,060 words) - 21:02, 23 January 2024
JUN, KLF6, KLF7, MYC, SMAD1, SMAD2, SMAD3, SOX11, SRF, STAT3, TP53, and XBP1. Several of these can also boost the regenerative capacity of CNS neurons...
34 KB (4,113 words) - 01:03, 12 July 2024