4-Hydroxycoumarin is a coumarin derivative with a hydroxy group at the 4-position. 4-Hydroxycoumarin is an important fungal metabolite from the precursor...

4-Hydroxycoumarins are a class of vitamin K antagonist (VKA) anticoagulant drug molecules. Chemically, they are derived from coumarin by adding a hydroxy...

4-hydroxycoumarin synthase (EC 2.3.1.208, BIS2, BIS3) is an enzyme with systematic name malonyl-CoA:2-hydroxybenzoyl-CoA malonyltransferase. This enzyme...

Hydroxycoumarin may refer to: 4-Hydroxycoumarin 7-Hydroxycoumarin (umbelliferone) This set index article lists chemical compounds articles associated...

anticoagulant prescription drugs, such as warfarin, are based on 4-hydroxycoumarin, a chemical derivative of coumarin initially isolated from this bean...

considered phenylpropanoids. Among the most important derivatives are the 4-hydroxycoumarins, which exhibit anticoagulant properties, a characteristic not present...

A well-known Michael reaction is the synthesis of warfarin from 4-hydroxycoumarin and benzylideneacetone first reported by Link in 1944: Several asymmetric...

incorrectly referred to as "coumadins" rather than 4-hydroxycoumarins. Some of the 4-hydroxycoumarin anticoagulant class of chemicals are designed to have...

which is formed from the 4-hydroxycoumarin and the ketone in the 3-position substituent. However, the existence of many 4-hydroxycoumadin anticoagulants...

is a potent anticoagulant rodenticide. It is a second-generation 4-hydroxycoumarin derivative and vitamin K antagonist, often called a "super-warfarin"...

addition to this specific metabolic disruption, massive toxic doses of 4-hydroxycoumarin, 4-thiochromenone and 1,3-indandione anticoagulants cause damage to...

can cause birth defects (teratogens). Coumarins (more accurately 4-hydroxycoumarins) are the most commonly used VKAs. In medicine, the most commonly used...

Brodifacoum is a highly lethal 4-hydroxycoumarin vitamin K antagonist anticoagulant poison. In recent years, it has become one of the world's most widely...

history. Identified in 1940, dicoumarol became the prototype of the 4-hydroxycoumarin anticoagulant drug class. Dicoumarol itself, for a short time, was...

Difenacoum is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type. It has anticoagulant effects and is used commercially as a rodenticide...

acids include bisphenol A, parabens, 1,2,3-triazole derivates, and 4-hydroxycoumarin and act as proton donors, changing the dye molecule between its leuco...

Flocoumafen is a fluorinated, second-generation anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type. It is a second generation (i.e., high potency)...

Hepatic Elimination half-life 8 to 11 hours Identifiers IUPAC name (RS)-4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one CAS Number 152-72-7 Y PubChem...

Coumatetralyl is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type used as a rodenticide. Coumatetralyl is commonly used with grains...

subset, 4-hydroxycoumarins, act as vitamin K antagonists. They block the regeneration and recycling of vitamin K. Some of the 4-hydroxycoumarin anticoagulant...

is used for metal extraction and plating and as a food additive. 4-Hydroxycoumarin - bicyclic analogue "New Sustainable Production Method Could Advance...

influence the dose needed to achieve the desired INR. Phenprocoumon, a 4-hydroxycoumarin structurally similar to warfarin, is a white to off-white crystalline...

benzylideneacetone results in a preparation of benzylacetone. The reaction of 4-Hydroxycoumarin with this compound yields Warfarin. Claisen, L. "Über die Einwirkung...

warfarin (in equilibrium with the hemiketal) in a Michael addition of 4-hydroxycoumarin and benzylideneacetone: A recent exploit is the vinyl alkylation of...

deficiency following treatment with anti-vitamin K anticoagulants (4-hydroxycoumarins, such as warfarin). Warfarin necrosis is a rare but severe complication...

3-azidocoumarin. The isomeric 4-azidocoumarin (CAS# 42373-56-8) product can also be prepared from 4-hydroxycoumarin via the 4-chloro derivative, which reacts...

and tested it; it turned out to be dicoumarol (3,3'-methylenebis-(4 hydroxycoumarin)). Dicoumarol was subjected to clinical trials in Wisconsin General...

Umbelliferone, also known as 7-hydroxycoumarin, hydrangine, skimmetine, and beta-umbelliferone, is a natural product of the coumarin family. It absorbs...

synthase EC 2.3.1.208: 4-hydroxycoumarin synthase EC 2.3.1.209: dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase EC 2.3.1.210: dTDP-4-amino-4,6-dideoxy-D-galactose...

chromatographic method for the estimation of phenprocoumon, 3-(1-phenyl-propyl)-4-hydroxycoumarin (marcoumar®, liquamar®), in human serum or plasma". Clinica Chimica...