An acetylcholine receptor (abbreviated AChR) or a cholinergic receptor is an integral membrane protein that responds to the binding of acetylcholine, a...
13 KB (1,300 words) - 18:52, 8 May 2024
Nicotinic acetylcholine receptors, or nAChRs, are receptor polypeptides that respond to the neurotransmitter acetylcholine. Nicotinic receptors also respond...
47 KB (4,776 words) - 23:03, 16 July 2024
Muscarinic acetylcholine receptors, or mAChRs, are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain...
31 KB (2,707 words) - 09:11, 16 June 2024
nicotine are derived from its effects on nicotinic acetylcholine receptors in the brain. Acetylcholine is a choline molecule that has been acetylated at...
38 KB (4,232 words) - 12:54, 20 November 2023
The muscarinic acetylcholine receptor M1, also known as the cholinergic receptor, muscarinic 1, is a muscarinic receptor that in humans is encoded by...
22 KB (2,221 words) - 04:29, 10 August 2024
muscarinic acetylcholine receptor, also known as cholinergic/acetylcholine receptor M3, or the muscarinic 3, is a muscarinic acetylcholine receptor encoded...
16 KB (1,761 words) - 18:13, 7 June 2024
The muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans...
19 KB (2,091 words) - 21:42, 27 March 2024
Anticholinergic (redirect from Acetylcholine receptor antagonist)
binding of ACh to muscarinic acetylcholine receptors; such agents do not antagonize the binding at nicotinic acetylcholine receptors at the neuromuscular junction...
25 KB (2,388 words) - 05:24, 21 July 2024
Muscarinic antagonist (redirect from Muscarinic receptor antagonists)
receptor antagonist (MRA), also called an antimuscarinic, is a type of anticholinergic agent that blocks the activity of the muscarinic acetylcholine...
40 KB (1,998 words) - 10:32, 22 May 2024
Parasympathomimetic drug (redirect from Acetylcholine receptor agonist)
nicotinic or muscarinic receptors (thus mimicking acetylcholine), or indirectly by inhibiting cholinesterase, promoting acetylcholine release, or other mechanisms...
7 KB (618 words) - 06:38, 29 April 2024
The muscarinic acetylcholine receptor M4, also known as the cholinergic receptor, muscarinic 4 (CHRM4), is a protein that, in humans, is encoded by the...
16 KB (1,853 words) - 03:12, 24 November 2022
nicotinic agonist is a drug that mimics the action of acetylcholine (ACh) at nicotinic acetylcholine receptors (nAChRs). The nAChR is named for its affinity for...
42 KB (4,258 words) - 23:15, 16 May 2024
The alpha-7 nicotinic receptor, also known as the α7 receptor, is a type of nicotinic acetylcholine receptor implicated in long-term memory, consisting...
26 KB (2,626 words) - 17:23, 19 June 2024
release acetylcholine (ACh), a small molecule neurotransmitter, which diffuses across the synaptic cleft and binds to nicotinic acetylcholine receptors (nAChRs)...
34 KB (4,062 words) - 14:11, 30 July 2024
The human muscarinic acetylcholine receptor M5, encoded by the CHRM5 gene, is a member of the G protein-coupled receptor superfamily of integral membrane...
13 KB (1,508 words) - 12:25, 16 January 2024
The alpha-4 beta-2 nicotinic receptor, also known as the α4β2 receptor, is a type of nicotinic acetylcholine receptor implicated in learning, consisting...
16 KB (1,639 words) - 00:34, 17 July 2024
electric signal which alters the cell excitability. The acetylcholine receptor is a receptor linked to a cation channel. The protein consists of four...
21 KB (2,456 words) - 22:14, 21 November 2023
Cholinergic (redirect from Receptors, cholinergic)
releasing acetylcholine, or butyrylcholine ("indirect-acting"), or mimicking their behaviours at one or more of the body's acetylcholine receptor ("direct-acting")...
9 KB (965 words) - 13:45, 21 December 2023
and Ipratropium bromide (all of which act as receptor antagonists of muscarinic acetylcholine receptors) are effective for treating asthma and COPD-related...
7 KB (718 words) - 00:07, 22 January 2024
Muscarinic agonist (redirect from Muscarinic receptor agonist)
agent that activates the activity of the muscarinic acetylcholine receptor. The muscarinic receptor has different subtypes, labelled M1-M5, allowing for...
7 KB (642 words) - 03:58, 16 December 2023
which results from antibodies that block or destroy nicotinic acetylcholine receptors (AChR) at the junction between the nerve and muscle. This prevents...
84 KB (8,872 words) - 03:05, 14 August 2024
muscarinic acetylcholine receptor positive allosteric modulator. KarXT (xanomeline/trospium) – combined M1 and M4 muscarinic acetylcholine receptor agonist...
10 KB (755 words) - 14:25, 16 August 2024
nicotinic receptor, also known as the α3β4 receptor and the ganglion-type nicotinic receptor, is a type of nicotinic acetylcholine receptor, consisting...
12 KB (1,100 words) - 23:20, 16 July 2024
This is accomplished via their action on the post-synaptic acetylcholine (Nm) receptors. In clinical use, neuromuscular block is used adjunctively to...
60 KB (6,864 words) - 05:14, 1 August 2024
Nicotinic antagonist (redirect from Nicotinic receptor antagonist)
anticholinergic drug that inhibits the action of acetylcholine (ACh) at nicotinic acetylcholine receptors. These compounds are mainly used for peripheral...
4 KB (172 words) - 22:07, 1 May 2024
up to 1.6%. Muscarine is a selective agonist of the muscarinic acetylcholine receptors. The name muscarine derives from that of Amanita muscaria, from...
18 KB (1,882 words) - 01:40, 28 June 2024
Acetylcholinesterase inhibitor (redirect from Acetylcholine esterase inhibitor)
autonomic ganglia and neuromuscular junctions, which are rich in acetylcholine receptors. Acetylcholinesterase inhibitors are one of two types of cholinesterase...
26 KB (2,387 words) - 03:29, 21 August 2024
Ligand-gated ion channel (redirect from Ionotropic receptor)
nicotinic acetylcholine receptor. It consists of a pentamer of protein subunits (typically ααβγδ), with two binding sites for acetylcholine (one at the...
29 KB (2,597 words) - 03:43, 7 April 2024
nicotinic acetylcholine receptor blockers (15), ecdysone receptor agonists (18), volgate-gated sodium channel blockers (22A and 22B), ryanodine receptor modulators...
32 KB (3,333 words) - 14:16, 30 June 2024
particular receptor is referred to as its endogenous ligand. E.g. the endogenous ligand for the nicotinic acetylcholine receptor is acetylcholine, but it...
26 KB (2,672 words) - 14:14, 22 July 2024