Acetylcholinesterase (HGNC symbol ACHE; EC 3.1.1.7; systematic name acetylcholine acetylhydrolase), also known as AChE, AChase or acetylhydrolase, is the...
35 KB (3,880 words) - 16:55, 22 July 2024
Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter...
26 KB (2,387 words) - 03:29, 21 August 2024
Sarin (category Acetylcholinesterase inhibitors)
acetylcholinesterase, allowing the muscle to relax. A build-up of acetylcholine in the synaptic cleft, due to the inhibition of acetylcholinesterase,...
46 KB (4,655 words) - 20:47, 5 October 2024
broken down by a choline esterase. The main type for that purpose is acetylcholinesterase (also called choline esterase I or erythrocyte cholinesterase); it...
17 KB (1,803 words) - 19:04, 26 March 2024
others. This group of inhibitors is divided into two subgroups, acetylcholinesterase inhibitors (AChEIs) and butyrylcholinesterase inhibitors (BChEIs)...
13 KB (1,105 words) - 12:13, 25 July 2024
conduction study. MG is generally treated with medications known as acetylcholinesterase inhibitors, such as neostigmine and pyridostigmine. Immunosuppressants...
82 KB (8,872 words) - 21:31, 17 October 2024
Malathion (category Acetylcholinesterase inhibitors)
Malathion is an organophosphate insecticide which acts as an acetylcholinesterase inhibitor. In the USSR, it was known as carbophos, in New Zealand and...
16 KB (1,448 words) - 07:30, 15 August 2024
Nerve agent (category Acetylcholinesterase inhibitors)
messages to organs. The disruption is caused by the blocking of acetylcholinesterase (AChE), an enzyme that catalyzes the breakdown of acetylcholine,...
56 KB (6,500 words) - 08:10, 8 September 2024
Galantamine (category Acetylcholinesterase inhibitors)
Galantamine is a type of acetylcholinesterase inhibitor. It is an alkaloid extracted from the bulbs and flowers of Galanthus nivalis (common snowdrop)...
35 KB (3,136 words) - 06:43, 7 September 2024
Pyridostigmine (category Acetylcholinesterase inhibitors)
Pyridostigmine is an acetylcholinesterase inhibitor in the cholinergic family of medications. It works by blocking the action of acetylcholinesterase and therefore...
11 KB (923 words) - 05:16, 2 October 2024
VX (nerve agent) (category Acetylcholinesterase inhibitors)
talc thickening agent. VX is an acetylcholinesterase inhibitor. It blocks the function of the enzyme acetylcholinesterase (AChE). Normally, when a motor...
49 KB (5,420 words) - 10:44, 6 October 2024
Huperzine A (category Acetylcholinesterase inhibitors)
is a reversible acetylcholinesterase inhibitor and NMDA receptor antagonist that crosses the blood–brain barrier. Acetylcholinesterase is an enzyme that...
14 KB (1,364 words) - 00:31, 7 September 2024
insecticides kill insects by reversibly inactivating the enzyme acetylcholinesterase (AChE inhibition) (IRAC mode of action 1a). The organophosphate pesticides...
30 KB (3,295 words) - 14:42, 16 July 2024
Physostigmine (category Acetylcholinesterase inhibitors)
Fraser at the University of Edinburgh in 1862. Physostigmine, an acetylcholinesterase inhibitor, can be used to treat glaucoma and delayed gastric emptying...
22 KB (2,351 words) - 17:51, 22 September 2024
Tomatine (section Inhibition of acetylcholinesterase)
of the enzyme acetylcholinesterase. The majority of synthetic pesticides used in agriculture work by inhibition of acetylcholinesterase to kill insects...
18 KB (2,070 words) - 03:39, 26 September 2024
concentration by using acetylcholinesterase inhibitors to inhibit acetylcholinesterase from breaking down acetylcholine. Current acetylcholinesterase inhibitors approved...
9 KB (972 words) - 03:17, 10 September 2024
Parathion (category Acetylcholinesterase inhibitors)
Entwicklungsnummer (German for "development number"). It is an irreversible acetylcholinesterase inhibitor. Safety concerns later led to the development of parathion...
13 KB (1,232 words) - 09:20, 27 September 2024
compounds called oximes that bind to organophosphate-inactivated acetylcholinesterase. It is used to treat organophosphate poisoning in conjunction with...
7 KB (678 words) - 08:59, 31 August 2024
the nucleus basalis of Meynert in the basal forebrain. The enzyme acetylcholinesterase converts acetylcholine into the inactive metabolites choline and...
41 KB (4,374 words) - 08:47, 16 October 2024
pesticides such as parathion are organophosphorus suicide inhibitors of acetylcholinesterase with aging times dependent on the lability of leaving groups present...
5 KB (588 words) - 20:27, 18 September 2024
Rivastigmine (category Acetylcholinesterase inhibitors)
Rivastigmine, sold under the brand name Exelon among others, is an acetylcholinesterase inhibitor used for the treatment of dementia associated with Alzheimer's...
21 KB (1,812 words) - 12:37, 12 October 2024
are approved for use in organic gardening Metaldehyde Niclosamide Acetylcholinesterase inhibitors (e.g. methiocarb), highly toxic to other animals and humans...
4 KB (345 words) - 03:07, 5 June 2024
Diisopropyl fluorophosphate (category Acetylcholinesterase inhibitors)
medicine, and as an experimental agent in neuroscience because of its acetylcholinesterase inhibitory properties and ability to induce delayed peripheral neuropathy...
10 KB (894 words) - 20:08, 30 August 2024
MSPI (nerve agent) (category Acetylcholinesterase inhibitors)
MSPI is an irreversible acetylcholinesterase inhibitor. MSPI reacts with the acetylcholinesterase to form an aged enzyme adduct that can't be reactivated...
1 KB (81 words) - 18:58, 15 September 2024
Donepezil (category Acetylcholinesterase inhibitors)
incontinence, and seizures. Donepezil is a centrally acting reversible acetylcholinesterase inhibitor and structurally unrelated to other anticholinesterase...
32 KB (2,835 words) - 20:05, 4 October 2024
Edrophonium (category Acetylcholinesterase inhibitors)
Edrophonium is a readily reversible acetylcholinesterase inhibitor. It prevents breakdown of the neurotransmitter acetylcholine and acts by competitively...
7 KB (612 words) - 08:21, 12 August 2023
Itopride (category Acetylcholinesterase inhibitors)
gastrointestinal conditions. It is a combined D2 receptor antagonist and acetylcholinesterase inhibitor. Itopride is the dimethoxy analog of trimethobenzamide...
17 KB (1,606 words) - 05:17, 31 May 2024
that newborns undergoing mechanical ventilation should not receive acetylcholinesterase inhibitors because these inhibitors may increase airway mucous secretions...
32 KB (3,804 words) - 06:12, 14 July 2024
at Edgewood Arsenal surrounded the modulation of Acetylcholine or Acetylcholinesterase, or the deactivation and reactivation of substances which did the...
54 KB (5,976 words) - 03:10, 9 October 2024
Acetylcholinesterase collagenic tail peptide also known as AChE Q subunit, acetylcholinesterase-associated collagen, or ColQ is the collagen-tail subunit...
9 KB (836 words) - 21:59, 13 June 2024