The aldol reaction (aldol addition) is a reaction in organic chemistry that combines two carbonyl compounds (e.g. aldehydes or ketones) to form a new...
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An aldol condensation is a condensation reaction in organic chemistry in which two carbonyl moieties (of aldehydes or ketones) react to form a β-hydroxyaldehyde...
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In organic chemistry, aldol reactions are acid- or base-catalyzed reactions of aldehydes or ketones. Aldol addition or aldolization refers to the addition...
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In organic chemistry, the Mukaiyama aldol addition is an organic reaction and a type of aldol reaction between a silyl enol ether (R2C=CR−O−Si(CH3)3) and...
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bond-formation reaction, giving them wide applicability as a precursor for a variety of other compounds. Aldols are usually synthesized from an aldol addition...
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Michael/aldol reaction (or domino Michael/aldol reaction) is a consecutive series of reactions composed of either Michael addition reactions or aldol reactions...
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Robinson annulation (redirect from Wichterle reaction)
transformations termed Tandem Michael-aldol reactions, that sequentially combine Michael addition and aldol reaction into a single reaction. As is the case with Robinson...
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Chiral auxiliary (section Aldol reactions)
stereoselective transformations, including aldol reactions, alkylation reactions, and Diels-Alder reactions. The oxazolidinones are substituted at the...
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active substrate; the reaction provides gramine derivatives. The Mannich reaction can be considered to involve a mixed-aldol reaction, dehydration of the...
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The reaction is catalyzed by a base and a divalent metal such as calcium. The intermediary steps taking place are aldol reactions, reverse aldol reactions...
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and Barbas-List reactions in organic chemistry are a family of proline-catalysed asymmetric aldol reactions. In the 1970s, two research groups...
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The Aldol–Tishchenko reaction is a tandem reaction involving an aldol reaction and a Tishchenko reaction. In organic synthesis, it is a method to convert...
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Allylic strain (section Aldol reaction)
oxazolidinone. There is another aspect of aldol reaction that is influenced by the allylic strain. On the second aldol reaction, the product which is a 1,3 dicarbonyl...
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Modified aldol tandem reaction is a sequential chemical transformation that combines aldol reaction with other chemical reactions that generate enolates...
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followed by the elimination of water in an E1cB dehydration reaction. Aldol reactions are a key reaction in organic chemistry because they provide a means of...
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Oxocarbenium (category Organic reactions)
and enantioselective acetate aldol addition reactions. The oxocarbenium ion is used as an electrophile in the reaction. When the methyl group increases...
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nucleophilic substitution, as well as being the co-discoverer of the aldol reaction. Borodin was a promoter of education in Russia and founded the School...
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Enolate (category Organic reactions)
(LDA). Often, as in conventional Claisen condensations, Mannich reactions, and aldol condensations, enolates are generated in low concentrations with...
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Stork enamine alkylation (redirect from Stork aldol reaction)
beta-unsaturated aldehyde or ketone hydrolysis of the enamine back to a ketone The reaction also applies to acyl halides as electrophiles, which results in the formation...
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components of an aldol reaction are combined with the asymmetric catalyst S-proline in a ball mill in a mechanosynthesis. The reaction product has 97%...
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aldol reaction in tandem with dynamic kinetic resolution to obtain a high enantioselective reaction. In this reaction proline catalyzes the reaction through...
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Unsaturated carbonyls can be prepared in the laboratory in an aldol reaction and in the Perkin reaction. α,β-Unsaturated carbonyl compounds can be subclassified...
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Self-condensation (category Condensation reactions)
organic reaction in which a chemical compound containing a carbonyl group (C=O) acts both as the electrophile and the nucleophile in an aldol condensation...
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Fructose-bisphosphate aldolase (section Reactions)
often just aldolase, is an enzyme catalyzing a reversible reaction that splits the aldol, fructose 1,6-bisphosphate, into the triose phosphates dihydroxyacetone...
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bond. These two steps are similar to a base-catalyzed aldol reaction. The oxygen anion in this aldol-like product then SN2 attacks on the formerly-nucleophilic...
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the Mitsunobu reaction. The aldol reaction is an essential tool for synthetic chemists. At its simplest, the aldol reaction involves two carbonyl compounds...
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Chiral Lewis acid (section Aldol reaction)
acid (BLA) catalyzes a number of diene-aldehyde cycloaddition reactions. In the aldol reaction, the diastereoselectivity of the product is often dictated...
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Reformatsky reaction an iodolactam is coupled with an aldehyde with triethylborane in toluene at -78 °C. Aldol reaction Blaise reaction Claisen condensation...
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Proline organocatalysis (section Reactions)
development of related reactions including the Michael addition, asymmetric aldol reaction, and the Mannich reaction. This reaction has likewise been used...
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with a C=C bond) and the resulting cyclobutane ring undergoes a retro-aldol reaction to yield a 1,5-diketone: The net effect is to add the two carbon atoms...
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