Anaphylatoxins, or complement peptides, are fragments (C3a, C4a and C5a) that are produced as part of the activation of the complement system. Complement...

U.S. National Library of Medicine. Gerard C, Gerard NP (1994). "C5A anaphylatoxin and its seven transmembrane-segment receptor". Annual Review of Immunology...

The anaphylatoxin receptors are a group of G-protein coupled receptors which bind anaphylatoxins. Members of this family include: C3a receptor C3AR1 C5a...

linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived...

enzyme found in plasma. It inactivates proteins such as bradykinin and anaphylatoxins in the blood in order to prevent toxic buildup. Lysine carboxypeptidase...

cleavage of complement component 3; the other is C3b. C3a is a 77 residue anaphylatoxin that binds to the C3a receptor (C3aR), a class A G protein-coupled receptor...

1016/0167-4781(95)00209-x. PMID 8605247. Ali H, Panettieri RA (February 2005). "Anaphylatoxin C3a receptors in asthma". Respiratory Research. 6 (1): 19. doi:10.1186/1465-9921-6-19...

able to more easily recognize and engulf pathogen molecules. While the anaphylatoxin C3a interacts with its C3a receptor (C3aR) to recruit leukocytes, C3b...

the response which can be augmented by the complement system via the anaphylatoxin C5a. Ligation of Fc receptors on the surfaces of immune effector cells...

may cause local increase of C5a. C5a is a chemotactic agent and an anaphylatoxin; it is essential in the innate immunity but it is also linked with the...

Subsequent investigation demonstrated that complement, specifically the anaphylatoxin C5a, can drive the Arthus reaction indirectly because the resultant...

usually rapidly cleaved by carboxypeptidase B. Both C3a and C5a have anaphylatoxin activity, directly triggering degranulation of mast cells as well as...

convertase activates C3 by cleaving the alpha chain, releasing C3a anaphylatoxin and generating C3b (beta chain + alpha' (alpha prime) chain). In humans...

molecules behave as chemoattractants, for example, C3a or C5a (the anaphylatoxins), and cause the leukocytes to move along a chemotactic gradient towards...

(degranulation) of substances from mast cells or basophils under the influence of anaphylatoxins. It causes difficulty in breathing which ranges from mild to severe...

structures. The amino-terminal domain I of fibulin consists of three anaphylatoxin-like (AT) modules, each approximately 40 residues long and containing...

(1 2) S Y (1 2 4 5) Neuromedin (B U (1 2)) Neurotensin (1 2) Other Anaphylatoxin (C3a C5a (1 2)) Angiotensin (1 2) Apelin Bombesin BRS3 GRPR NMBR) Bradykinin...

(1 2) S Y (1 2 4 5) Neuromedin (B U (1 2)) Neurotensin (1 2) Other Anaphylatoxin (C3a C5a (1 2)) Angiotensin (1 2) Apelin Bombesin BRS3 GRPR NMBR) Bradykinin...

(1 2) S Y (1 2 4 5) Neuromedin (B U (1 2)) Neurotensin (1 2) Other Anaphylatoxin (C3a C5a (1 2)) Angiotensin (1 2) Apelin Bombesin BRS3 GRPR NMBR) Bradykinin...

(1 2) S Y (1 2 4 5) Neuromedin (B U (1 2)) Neurotensin (1 2) Other Anaphylatoxin (C3a C5a (1 2)) Angiotensin (1 2) Apelin Bombesin BRS3 GRPR NMBR) Bradykinin...

(GHSR) InterPro: IPR003905 GPR39 (GPR39) Motilin receptor (MLNR, GPR38) Anaphylatoxin receptors InterPro: IPR002234 C3a receptor (C3AR1, C3AR) C5a receptor...

factor, and leukotrienes); peptide hormones (e.g., calcitonin, C5a anaphylatoxin, follicle-stimulating hormone [FSH], gonadotropin-releasing hormone...

(1 2) S Y (1 2 4 5) Neuromedin (B U (1 2)) Neurotensin (1 2) Other Anaphylatoxin (C3a C5a (1 2)) Angiotensin (1 2) Apelin Bombesin BRS3 GRPR NMBR) Bradykinin...

(1 2) S Y (1 2 4 5) Neuromedin (B U (1 2)) Neurotensin (1 2) Other Anaphylatoxin (C3a C5a (1 2)) Angiotensin (1 2) Apelin Bombesin BRS3 GRPR NMBR) Bradykinin...

smaller fragments of proteolysis, C4a and C2a are released. C4a is an anaphylatoxin. C3 convertases are unstable (half-life 10 – 20 min) – respectively...

(1 2) S Y (1 2 4 5) Neuromedin (B U (1 2)) Neurotensin (1 2) Other Anaphylatoxin (C3a C5a (1 2)) Angiotensin (1 2) Apelin Bombesin BRS3 GRPR NMBR) Bradykinin...

(1 2) S Y (1 2 4 5) Neuromedin (B U (1 2)) Neurotensin (1 2) Other Anaphylatoxin (C3a C5a (1 2)) Angiotensin (1 2) Apelin Bombesin BRS3 GRPR NMBR) Bradykinin...

(1 2) S Y (1 2 4 5) Neuromedin (B U (1 2)) Neurotensin (1 2) Other Anaphylatoxin (C3a C5a (1 2)) Angiotensin (1 2) Apelin Bombesin BRS3 GRPR NMBR) Bradykinin...

(1 2) S Y (1 2 4 5) Neuromedin (B U (1 2)) Neurotensin (1 2) Other Anaphylatoxin (C3a C5a (1 2)) Angiotensin (1 2) Apelin Bombesin BRS3 GRPR NMBR) Bradykinin...

permeability can be increased by the release of certain cytokines, anaphylatoxins, or other mediators (such as leukotrienes, prostaglandins, histamine...