Atezolizumab, sold under the brand name Tecentriq among others, is a monoclonal antibody medication used to treat urothelial carcinoma, non-small cell...
43 KB (4,164 words) - 02:04, 16 July 2024
combination of tiragolumab and atezolizumab reduced the risk of disease progression or death by 38% compared to atezolizumab monotherapy. In a subset of...
18 KB (2,103 words) - 17:00, 19 July 2024
Atezolizumab (Tecentriq) is a fully humanised IgG1 (immunoglobulin 1) antibody developed by Roche Genentech. In 2016, the FDA approved atezolizumab for...
31 KB (3,266 words) - 05:29, 20 May 2024
carboplatin plus etoposide and were randomized to receive atezolizumab or placebo. Atezolizumab was associated with a significant improvement in overall...
54 KB (5,529 words) - 09:35, 4 August 2024
chemotherapy plus Bevacizumab, chemotherapy plus atezolizumab or chemotherapy plus Bevacizumab and atezolizumab. The chemotherapy used was Carboplatin, and...
59 KB (6,487 words) - 18:42, 27 December 2023
Epizyme's EZH2 inhibitor tazemetostat would be synergistic with Genentech's atezolizumab. In August 2016, the company began a collaboration with Carmot Therapeutics...
32 KB (2,862 words) - 04:08, 6 August 2024
cells, and result in decreased tumor cell kill by the immune system. Atezolizumab is an anti PD-L1 monoclonal antibody. Nivolumab and Pembrolizumab are...
51 KB (5,338 words) - 00:03, 27 August 2024
eligible for any platinum based chemotherapy and have PD-L1 expression, Atezolizumab and Pembrolizumab can be used.[citation needed] People with bone metastasis...
106 KB (11,035 words) - 15:14, 31 August 2024
inactivate BRCA1 or BRCA2. The immune checkpoint inhibitor antibody atezolizumab for those whose tumors express PD-L1. And the similar immunotherapy pembrolizumab...
132 KB (14,894 words) - 12:18, 31 August 2024
sometimes effective in those that do not. Treatment with pembrolizumab, atezolizumab, or combination nivolumab plus ipilimumab are all superior to chemotherapy...
90 KB (9,784 words) - 14:55, 21 June 2024
parkinson's disease, licensed by Mylan and Bausch Health. Tecentriq (atezolizumab), for non-small cell lung cancer. TNKase (tenecteplase), for heart attacks...
55 KB (5,124 words) - 05:32, 27 August 2024
had undergone surgery then received atezolizumab, an immune checkpoint inhibitor. 16 of the patients on atezolizumab then received autogene cevumeran. 1...
4 KB (428 words) - 02:01, 21 January 2024
treat both solid tumors and lymphomas. In May 2016, PD-L1 inhibitor atezolizumab was approved for treating bladder cancer. Other modes of enhancing [adoptive]...
21 KB (2,093 words) - 02:41, 1 September 2024
yet FDA- or other regulator-approved treatment, except PDL1 inhibitor atezolizumab for the ultra-rate diagnosis of alveolar soft part sarcoma. Other strategies...
37 KB (4,087 words) - 23:54, 14 August 2024
part sarcoma has a regulatory approval for such an agent, in this case atezolizumab. When the immunological constant of rejection signature (ICR) was retrospectively...
25 KB (2,419 words) - 22:29, 14 August 2024
certainty evidence. In May 2016, the FDA granted accelerated approval to atezolizumab for locally advanced or metastatic urothelial carcinoma treatment after...
19 KB (1,970 words) - 15:42, 9 August 2024
Larkins E, Vallejo J, Li X, et al. (May 2021). "FDA Approval Summary: Atezolizumab and Durvalumab in Combination with Platinum-Based Chemotherapy in Extensive...
28 KB (2,721 words) - 20:03, 22 August 2024
sunitinib), checkpoint inhibitors (e.g. ipilimumab, nivolumab, pembrolizumab, atezolizumab) Contrast agent Gadolininum based contrast agent Other Allopurinol, Chinese...
20 KB (2,303 words) - 18:34, 27 July 2024
is a phase 3, randomized study of zanzalintinib in combination with atezolizumab versus regorafenib in metastatic colorectal cancer. STELLAR-304 (NCT05678673)...
5 KB (188 words) - 23:55, 23 January 2024
gamma receptor I) in early clinical trials. In May 2016, PD-L1 inhibitor atezolizumab was approved for treating bladder cancer. Anti-PD-L1 antibodies currently...
89 KB (10,338 words) - 14:21, 16 July 2024
in clinical trials. Clinically available examples include durvalumab, atezolizumab and avelumab. In normal tissue, feedback between transcription factors...
24 KB (3,052 words) - 08:26, 20 August 2024
(1 June 2022). "GALLANT-1: Galectin-3 (Gal-3) inhibitor GB1211 plus atezolizumab (atezo) in patients with non–small cell lung cancer (NSCLC)—A randomized...
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instance, in the recent phase III trial IMBrave 150, the combination of atezolizumab and bevacizumab was found to improve both overall and progression-free...
90 KB (10,116 words) - 05:33, 31 August 2024
pembrolizumab (Keytruda), Roche (via its subsidiary Genentech) with atezolizumab, GlaxoSmithKline in collaboration with the Maryland biotech company Amplimmune;...
47 KB (4,870 words) - 15:14, 3 August 2024
pidilizumab (CT-011, Cure Tech) and BMS-936559 (Bristol Myers Squibb). Both atezolizumab (MPDL3280A, Roche) and avelumab (Merck KGaA, Darmstadt, Germany and Pfizer)...
39 KB (5,010 words) - 05:27, 17 August 2024
trials reported TNBC results in June 2016, for IMMU-132, Vantictumab, and atezolizumab in combination with the chemotherapy nab-paclitaxel. In 2019, CytoDyn...
28 KB (3,411 words) - 03:40, 14 June 2024
trials demonstrating promising effects. Specific drugs being tested are atezolizumab, pembrolizumab, and spartalizumab, amongst others. Combinatorial therapy...
20 KB (2,157 words) - 02:36, 2 September 2024
are many chemotherapeutic drugs approved for liver cancer including: atezolizumab, nivolumab, pembrolizumab, regorafenib. Increasingly, immunotherapy agents...
57 KB (6,080 words) - 08:47, 12 August 2024
Aselizumab mab humanized L-selectin (CD62L) severely injured patients Atezolizumab Tecentriq mab humanized PD-L1 Y cancer Atidortoxumab mab human Staphylococcus...
136 KB (4,020 words) - 07:14, 15 August 2024
are currently being conducted for new targeted treatments, including: atezolizumab, varlilumab, durvalumab, avelumab, LAG525, MBG453, TRC105, and savolitinib...
101 KB (10,959 words) - 01:32, 22 August 2024