• An autoantibody is an antibody (a type of protein) produced by the immune system that is directed against one or more of the individual's own proteins...
    18 KB (1,555 words) - 19:01, 1 March 2024
  • decarboxylase autoantibodies (GADA), islet cell autoantibodies (ICA), insulinoma-associated (IA-2) autoantibodies, and zinc transporter autoantibodies (ZnT8)...
    28 KB (3,080 words) - 17:18, 27 December 2023
  • Antithyroid autoantibodies (or simply antithyroid antibodies) are autoantibodies targeted against one or more components on the thyroid. The most clinically...
    13 KB (1,515 words) - 00:19, 2 December 2023
  • Thumbnail for Antinuclear antibody
    Antinuclear antibodies (ANAs, also known as antinuclear factor or ANF) are autoantibodies that bind to contents of the cell nucleus. In normal individuals, the...
    54 KB (6,097 words) - 21:43, 28 June 2024
  • Thumbnail for Anti-SSA/Ro autoantibodies
    Anti-SSA autoantibodies (anti–Sjögren's-syndrome-related antigen A autoantibodies, also called anti-Ro, or similar names including anti-SSA/Ro, anti-Ro/SSA...
    14 KB (1,783 words) - 03:28, 12 August 2023
  • Thumbnail for Immunoglobulin G
    transplantation. In a mouse model of autoantibody mediated anemia using IgG isotype switch variants of an anti erythrocytes autoantibody, it was found that mouse...
    18 KB (2,098 words) - 13:43, 12 August 2024
  • phenotype neuromyelitis optica and in general all the spectrum of MOG autoantibody-associated demyelinating diseases. Eastern equine encephalitis, Japanese...
    3 KB (300 words) - 13:11, 18 May 2024
  • Thumbnail for Adrenergic receptor autoantibodies
    Adrenergic receptor autoantibodies The adrenergic receptors (or adrenoreceptors) are a class of cell membrane-bound protein receptors throughout the body...
    15 KB (1,636 words) - 05:57, 15 April 2024
  • Anti-transglutaminase antibodies (category Autoantibodies)
    Anti-transglutaminase antibodies (ATA) are autoantibodies against the transglutaminase protein. Detection is considered abnormal, and may indicate one...
    18 KB (1,860 words) - 02:34, 10 March 2024
  • Rheumatoid factor (category Autoantibodies)
    Rheumatoid factor (RF) is the autoantibody that was first found in rheumatoid arthritis. It is defined as an antibody against the Fc portion of IgG and...
    11 KB (1,205 words) - 08:02, 5 June 2024
  • Thumbnail for Glutamate decarboxylase
    and cognitive areas of the brain. Both GAD67 and GAD65 are targets of autoantibodies in people who later develop type 1 diabetes mellitus or latent autoimmune...
    42 KB (4,772 words) - 16:29, 17 May 2024
  • Thumbnail for Demyelinating disease
    A demyelinating disease refers to any disease affecting the nervous system where the myelin sheath surrounding neurons is damaged. This damage disrupts...
    24 KB (2,701 words) - 21:14, 9 March 2024
  • Thumbnail for Myositis
    (known as inflammatory myopathies) that typically test positive for autoantibodies are dermatomyositis, polymyositis, and inclusion body myositis. Other...
    11 KB (1,020 words) - 05:31, 10 August 2024
  • Thumbnail for Autoimmune disease
    characterized by development of autoantibodies to thyroid-stimulating hormone (TSH) receptors (TRAb). The binding of TRAb autoantibodies to TSH receptor results...
    63 KB (6,919 words) - 19:02, 7 August 2024
  • malignancy, or any other underlying disease. Cold agglutinins (CA) are autoantibodies that agglutinate RBCs with a temperature optimum of 3-4 °C but may also...
    19 KB (1,683 words) - 04:21, 20 July 2024
  • Thumbnail for Hashimoto's thyroiditis
    Diagnosis is confirmed with blood tests for TSH, T4, and antithyroid autoantibodies. Other conditions that can produce similar symptoms include Graves'...
    72 KB (7,888 words) - 02:12, 28 August 2024
  • Thumbnail for Chronic inflammatory demyelinating polyneuropathy
    (CCPD) could be produced by neurofascins. Autoantibodies to components of the Ranvier nodes, specially autoantibodies the Contactin-associated protein 1 (CASPR)...
    46 KB (5,010 words) - 13:32, 26 July 2024
  • Thumbnail for Congenital heart block
    cardiomyocytes, the links between this autoantibody and autoimmune CHB are less strong than the anti-Ro autoantibody and it usually accompanies it in the...
    25 KB (2,851 words) - 03:05, 3 December 2023
  • Anti-histone antibodies are autoantibodies that are a subset of the anti-nuclear antibody family, which specifically target histone protein subunits or...
    6 KB (639 words) - 23:05, 14 September 2023
  • Thumbnail for C-ANCA
    C-ANCA (category Autoantibodies)
    or PR3-ANCA, or antineutrophil cytoplasmic antibodies, are a type of autoantibody, an antibody produced by the body that acts against one of its own proteins...
    1 KB (127 words) - 14:54, 28 July 2024
  • Disease Autoantibody target Autoimmune hemolytic anemia Red blood cells Goodpasture syndrome Glomerular basement membrane Graves disease Thyroid stimulating...
    6 KB (486 words) - 03:52, 28 November 2023
  • Thumbnail for Autoimmune urticaria
    urticaria, is a type of chronic urticaria characterized by the presence of autoantibodies in the patient's immune system that target the body's own mast cells...
    35 KB (3,673 words) - 06:34, 15 January 2024
  • Thumbnail for Antisynthetase syndrome
    myositis-specific autoantibodies such as anti-MDA5 autoantibodies, anti-Mi-2 autoantibodies, and anti-signal recognition particle autoantibodies. Autoantibodies often...
    57 KB (5,502 words) - 04:57, 9 August 2024
  • Thumbnail for Pemphigus
    derived from the Greek root pemphix, meaning "blister". In pemphigus, autoantibodies form against desmoglein, which forms the "glue" that attaches adjacent...
    19 KB (1,951 words) - 13:36, 28 May 2024
  • Thumbnail for Anti-neutrophil cytoplasmic antibody
    Anti-neutrophil cytoplasmic antibody (category Autoantibodies)
    Anti-neutrophil cytoplasmic antibodies (ANCAs) are a group of autoantibodies, mainly of the IgG type, against antigens in the cytoplasm of neutrophils...
    20 KB (2,272 words) - 06:48, 24 August 2024
  • transfused and transfusion-naive patients, suggesting that antikinectin autoantibody development was not due to transfusion-related alloreactivity. Negative...
    40 KB (4,353 words) - 21:26, 6 September 2024
  • IgM-mediated. AIHA cannot be attributed to any single autoantibody. To determine the autoantibody or autoantibodies present in a patient, the Coombs test, also...
    26 KB (3,084 words) - 06:51, 20 July 2024
  • Thumbnail for Diabetes
    adults Body size Thin or normal Often obese Ketoacidosis Common Rare Autoantibodies Usually present Absent Endogenous insulin Low or absent Normal, decreased...
    128 KB (12,971 words) - 04:40, 13 September 2024
  • Thumbnail for Postural orthostatic tachycardia syndrome
    levels of autoantibodies against the α1-adrenergic receptor and against the muscarinic acetylcholine M4 receptor. Elevations of autoantibodies targeting...
    97 KB (9,980 words) - 23:57, 17 August 2024
  • Thumbnail for Anorexia nervosa
    (2013). "The role of "mixed" orexigenic and anorexigenic signals and autoantibodies reacting with appetite-regulating neuropeptides and peptides of the...
    156 KB (17,628 words) - 05:44, 13 September 2024