Axonal transport, also called axoplasmic transport or axoplasmic flow, is a cellular process responsible for movement of mitochondria, lipids, synaptic...

Diffuse axonal injury (DAI) is a brain injury in which scattered lesions occur over a widespread area in white matter tracts as well as grey matter. DAI...

axonal region. Proteins needed for the growth of the axon, and the removal of waste materials, need a framework for transport. This axonal transport is...

cargoes are transported at a fast rate or a slow rate. The fast axonal transport has a rate of 50–500 mm per day, while the slow axonal transport was found...

defects in protein transport machinery and regulation, such as RAB1, may play a role in this disease mechanism. Impaired axonal transport of alpha-synuclein...

in the neuron's cell body (soma) or dendrites. In axonal transport (also known as axoplasmic transport) materials are carried through the axoplasm to or...

occurs in many neurodegenerative diseases, especially those where axonal transport is impaired such as amyotrophic lateral sclerosis (ALS) and Alzheimer's...

molecular weight; NF-H). These proteins were discovered from studies of axonal transport and are often referred to as the "neurofilament triplet". However,...

to recruit signaling proteins and to regulate microtubule-mediated axonal transport. Tau is a negative regulator of mRNA translation in Drosophila, mouse...

There is evidence suggesting that it could be due to defects in the axonal transport of mitochondria. Increasing evidence suggests a possible link between...

and retrograde axonal transport is impaired. Between 30-50mmHg there will usually be changes in intraneural blood flow, axonal transport, and vascular...

consequential accumulation as a result of decreased axonal transport. This reduced axonal transport can then cause swelling or bulging on the surface layer...

dysfunction leading to dysfunctional motor neuron axonal homeostasis (reduced axonal length and fast axonal transport of mitochondrial cargo) has been shown to...

nerve trunks and into the central nervous system (CNS) by retrograde axonal transport by using dyneins. The tetanus toxin protein has a molecular weight...

including mitosis, meiosis and transport of cellular cargo, such as in axonal transport, and intraflagellar transport. Most kinesins walk towards the...

techniques are based on the visualization of the biological process of axonal transport. The anterograde and retrograde tracing techniques allow the detailed...

expressed abundantly in neurons, suggesting its role in axons as an axonal transport motor. To further elucidate the function of KIF1A, in vivo studies...

calcify in the optic disc. They are thought to be the remnants of the axonal transport system of degenerated retinal ganglion cells. ODD have also been referred...

axonal transport contributes to pathogenesis in multiple neurodegenerative diseases. It is proposed that protein aggregations due to faulty transport...

muscle tissue, to the spinal cord through nerve pathways via retrograde axonal transport. A third hypothesis is that the virus is imported into the CNS via...

body in a process called retrograde axonal transport. Additionally, dynein motor is also responsible for the transport of degradative endosomes retrogradely...

function of huntingtin (Htt) is not well understood but it is involved in axonal transport. Huntingtin is essential for development, and its absence is lethal...

Gajdusek, Daniel Carleton (1985). "Hypothesis: interference with axonal transport of neurofilament as a common pathogenetic mechanism in certain diseases...

Fundamental Research, Mumbai. Her main area of interest is regulation of axonal transport within nerve cells. She is a recipient of the International Early Career...

2014). "Rabies Virus Hijacks and accelerates the p75NTR retrograde axonal transport machinery". PLOS Pathogens. 10 (8): e1004348. doi:10.1371/journal.ppat...

An additional feature of a low-energy state is failure to maintain axonal transport via dynein/kinesin ATPases, which in many diseases results in neuronal...

transported more slowly. Vesicles and other organelles are also increased at the nodes, which suggest that there is a bottleneck of axonal transport in...

PINK1 across OMM. Miro (or RHOT1/RHOT2) is an OMM protein critical for axonal transport, and may be ubiquitinated and targeted towards proteasomal degradation...

body of the neuron and then transported via fast axonal transport down to the axon terminal. Small clear core vesicles transport small molecule neurotransmitters...

is transported to the anterior pituitary through the portal blood vessel system of the hypophyseal stalk and vasopressin is transported by axonal transport...