• Thumbnail for Ciliary neurotrophic factor
    Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene. The protein encoded by this gene is a polypeptide hormone and neurotrophic...
    15 KB (1,740 words) - 14:38, 3 December 2023
  • unknown. The CNTF family of neurotrophic factors includes ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), interleukin-6 (IL-6),...
    16 KB (1,784 words) - 04:08, 6 January 2024
  • The ciliary neurotrophic factor receptor, also known as CNTFR, binds the ciliary neurotrophic factor. This receptor and its cognate ligand support the...
    2 KB (146 words) - 00:52, 1 December 2023
  • Thumbnail for Glial scar
    also been shown to increase astrocyte proliferation in vitro. Ciliary neurotrophic factor (CNTF) is a cytosolic protein that is not secreted. CNTF has...
    24 KB (2,962 words) - 15:40, 7 June 2024
  • Thumbnail for Nerve injury
    important role in not only producing neurotrophic factors such as nerve growth factor (NGF) and ciliary neurotrophic factor (CNTF), which promote growth, of...
    34 KB (4,113 words) - 01:03, 12 July 2024
  • brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), and ciliary neurotrophic factor (CNTF)...
    13 KB (1,177 words) - 18:50, 10 July 2024
  • motility factor Bone morphogenetic proteins (BMPs) Ciliary neurotrophic factor family Ciliary neurotrophic factor (CNTF) Leukemia inhibitory factor (LIF)...
    10 KB (1,131 words) - 19:14, 31 March 2024
  • Thumbnail for Leukemia inhibitory factor receptor
    affect other systems, including the ciliary neurotrophic factor, growth hormone and prolactin. Leukemia inhibitory factor receptor has been shown to interact...
    11 KB (1,325 words) - 16:37, 6 April 2024
  • kinase, Akt, and PKC pathways. CNTF: Ciliary neurotrophic factor is another protein that acts as a survival factor for motor neurons. CNTF acts via a receptor...
    52 KB (6,298 words) - 18:13, 4 July 2024
  • Thumbnail for Interleukin-6 receptor
    Interleukin-6 receptor has been shown to interact with Interleukin 6 and ciliary neurotrophic factor. Cluster of differentiation Anti-IL-6 Tocilizumab, a monoclonal...
    11 KB (1,438 words) - 14:27, 22 December 2023
  • Thumbnail for Azad Bonni
    he discovered signaling mechanisms by which neurotrophic factors, including ciliary neurotrophic factor (CNTF) and neurotrophins, induce transcription...
    4 KB (339 words) - 15:46, 8 September 2023
  • Thumbnail for CLCF1
    closely related to other proteins called cardiotrophin-1 and ciliary neurotrophic factor. GRCh38: Ensembl release 89: ENSG00000175505 – Ensembl, May 2017...
    7 KB (861 words) - 23:29, 8 November 2023
  • derived neurotrophic factor (GDNF), and ciliary neurotrophic factor (CNTF) was presented to Dorsal root ganglion cultures in vitro. One factor from each...
    106 KB (14,549 words) - 22:54, 1 July 2024
  • Thumbnail for Glycoprotein 130
    such as cardiotrophin 1 (CT-1), leukemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), oncostatin M (OSM), and IL-11. There are also...
    18 KB (2,202 words) - 01:16, 14 June 2024
  • Thumbnail for Janus kinase 1
    IL-6R, IL-11R, LIF-R, OSM-R, cardiotrophin-1 receptor (CT-1R), ciliary neurotrophic factor receptor (CNTF-R), neurotrophin-1 receptor (NNT-1R) and Leptin-R)...
    21 KB (2,423 words) - 03:55, 27 January 2024
  • Thumbnail for Neurotrophin
    to these four neurotrophins, the GDNF family of ligands, and ciliary neurotrophic factor (CNTF), among other biomolecules. Neurotrophin-6 and neurotrophin-7...
    27 KB (3,071 words) - 04:54, 3 June 2024
  • Thumbnail for CRLF1
    complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival...
    7 KB (931 words) - 16:56, 15 February 2024
  • include the cytokines interleukin 6 (IL-6), ciliary neurotrophic factor (CNTF), and leukemia inhibitory factor (LIF). Although many of these specific modulatory...
    30 KB (3,598 words) - 18:28, 7 June 2024
  • Thumbnail for Retinal pigment epithelium
    insulin-like growth factor-1 (IGF-1), ciliary neurotrophic factor (CNTF), platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), lens...
    9 KB (1,181 words) - 23:04, 9 May 2024
  • Zinc finger protein 91 homolog (mouse), ciliary neurotrophic factor transcription unit, also known as ZFP91-CNTF, is a human gene. The genes ZFP91 and...
    4 KB (509 words) - 09:07, 10 June 2024
  • Thumbnail for Interleukin 6
    Interleukin 6 (category Neurotrophic factors)
    Interleukin 27 (IL-27), ciliary neurotrophic factor (CNTF), cardiotrophin-1 (CT-1), cardiotrophin-like cytokine (CLC), leukemia inhibitory factor (LIF), oncostatin...
    63 KB (7,455 words) - 14:38, 9 July 2024
  • Thumbnail for Macular telangiectasia
    (neovascularisation), treatment with Anti-VEGF can be helpful. Ciliary neurotrophic factor (CNTF) is believed to have neuroprotective properties and could...
    19 KB (2,217 words) - 18:58, 27 September 2023
  • Thumbnail for Astrogliosis
    insult. Upregulation of GFAP, which is induced by FGF, TGFB, and ciliary neurotrophic factor (CNTF), is a classic marker for reactive gliosis. Axon regeneration...
    19 KB (2,179 words) - 01:12, 8 November 2023
  • Thumbnail for Tyrosine kinase 2
    cytokines, including IL-6, IL-11, IL-27, IL-31, oncostatin M (OSM), ciliary neurotrophic factor, cardiotrophin 1, cardiotrophin-like cytokine, and LIF, TYK2...
    25 KB (2,850 words) - 23:00, 12 November 2023
  • Thumbnail for Wallerian degeneration
    neurotrophic factor, ciliary neurotrophic factor, leukemia inhibitory factor, insulin-like growth factor, and fibroblast growth factor. These factors...
    41 KB (5,080 words) - 23:57, 25 November 2023
  • Thumbnail for Interleukin 11 receptor alpha subunit
    receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure...
    8 KB (1,049 words) - 07:02, 13 May 2024
  • Thumbnail for Neurotrophin-3
    this gene, NT-3, is a neurotrophic factor in the NGF (Nerve Growth Factor) family of neurotrophins. It is a protein growth factor which has activity on...
    14 KB (1,816 words) - 04:39, 31 October 2023
  • Thumbnail for Paul A. Sieving
    group conducted the first human clinical trial of ciliary neurotrophic factor (CNTF) as a rescue factor for retinitis pigmentosa. His lab studies potential...
    8 KB (921 words) - 07:37, 3 December 2023
  • Thumbnail for George Yancopoulos
    Aldrich TH, Valenzuela DM, et al. (July 1991). "The receptor for ciliary neurotrophic factor". Science. 253 (5015): 59–63. Bibcode:1991Sci...253...59D. doi:10...
    24 KB (2,391 words) - 20:00, 9 April 2024
  • brain derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin-4/5 (NT-4/5). Other factors are ciliary neurotrophic factor (CNTF), glial...
    35 KB (4,319 words) - 21:07, 12 June 2024