• Thumbnail for Eosinophil
    Eosinophils, sometimes called eosinophiles or, less commonly, acidophils, are a variety of white blood cells and one of the immune system components responsible...
    29 KB (3,166 words) - 00:19, 9 September 2024
  • Thumbnail for Eosinophilia
    eosinophil count in the peripheral blood exceeds 5×108/L (500/μL). Hypereosinophilia is an elevation in an individual's circulating blood eosinophil count...
    50 KB (5,515 words) - 14:42, 21 September 2024
  • Thumbnail for Eosinophil peroxidase
    Eosinophil peroxidase is an enzyme found within the eosinophil granulocytes, innate immune cells of humans and mammals. This oxidoreductase protein is...
    24 KB (2,880 words) - 08:18, 10 March 2024
  • Thumbnail for White blood cell
    diseases. Types of white blood cells are granulocytes (neutrophils, eosinophils, and basophils), and agranulocytes (monocytes, and lymphocytes (T cells...
    32 KB (3,210 words) - 07:13, 7 September 2024
  • Thumbnail for Major basic protein
    Eosinophil major basic protein, often shortened to major basic protein (MBP; also called Proteoglycan 2 (PRG2)) is encoded in humans by the PRG2 gene....
    13 KB (1,515 words) - 04:45, 27 January 2024
  • Thumbnail for Hypereosinophilic syndrome
    syndrome is a disease characterized by a persistently elevated eosinophil count (≥ 1500 eosinophils/mm³) in the blood for at least six months without any recognizable...
    26 KB (2,491 words) - 20:07, 10 September 2024
  • Thumbnail for Eosinopenia
    condition where the number of eosinophils, a type of white blood cell, in circulating blood is lower than normal. Eosinophils are a type of granulocyte and...
    15 KB (1,693 words) - 15:08, 25 April 2024
  • Thumbnail for Eosinophil cationic protein
    Eosinophil cationic protein (ECP) also known as ribonuclease 3 is a basic protein located in the eosinophil primary matrix. In humans, the eosinophil...
    19 KB (2,337 words) - 06:15, 3 June 2024
  • Thumbnail for Eosinophil-derived neurotoxin
    Eosinophil-derived neurotoxin is an enzyme that in humans is encoded by the RNASE2 gene. The protein encoded by this gene is found in eosinophil granulocytes...
    8 KB (999 words) - 05:11, 25 December 2023
  • Thumbnail for Prurigo nodularis
    CM (August 2000). "Eosinophil cationic protein- and eosinophil-derived neurotoxin/eosinophil protein X-immunoreactive eosinophils in prurigo nodularis"...
    14 KB (1,489 words) - 12:27, 7 September 2024
  • Thumbnail for Eosinophilic granulomatosis with polyangiitis
    rhinitis. The second stage is characterized by abnormally high numbers of eosinophils (hypereosinophilia), which causes tissue damage, most commonly to the...
    28 KB (2,682 words) - 19:53, 23 August 2024
  • Thumbnail for Eosinophilic esophagitis
    involves eosinophils, a type of white blood cell. In healthy individuals, the esophagus is typically devoid of eosinophils. In EoE, eosinophils migrate...
    32 KB (3,642 words) - 13:22, 13 September 2024
  • Thumbnail for Granulocyte
    granulocytes", the most abundant of the granulocytes; the other types (eosinophils, basophils, and mast cells) have varying morphology. Granulocytes are...
    23 KB (2,454 words) - 02:29, 31 August 2024
  • Thumbnail for Interleukin 5
    immunoglobulin secretion—primarily IgA. It is also a key mediator in eosinophil activation. IL-5 is a 115-amino acid (in human, 133 in the mouse) -long...
    13 KB (1,523 words) - 19:27, 26 June 2024
  • type of white blood cell, the eosinophil. Typically, the disorder is associated with hypereosinophilia, i.e. an eosinophil blood cell count greater than...
    32 KB (3,610 words) - 06:12, 8 September 2024
  • hypereosinophilia (i.e. a large or extremely large increase in the number of eosinophils in the blood circulation) is caused by an aberrant population of lymphocytes...
    20 KB (2,341 words) - 00:22, 25 November 2023
  • disorder characterized by the presence of sustained elevations in blood eosinophil levels that reach ranges diagnostic of eosinophilia (i.e. 500–1500/microliter)...
    13 KB (1,439 words) - 16:22, 3 December 2023
  • Thumbnail for Eotaxin
    chemokine subfamily of eosinophil chemotactic proteins. Eotaxin is a special CC chemokine because it primarily attracts eosinophils. By being a chemoattractant...
    10 KB (1,309 words) - 17:45, 5 May 2024
  • Thumbnail for Fc receptor
    follicular dendritic cells, natural killer cells, macrophages, neutrophils, eosinophils, basophils, human platelets, and mast cells – that contribute to the...
    42 KB (4,735 words) - 03:31, 26 March 2024
  • Thumbnail for Dupilumab
    sores, and increased blood levels of a type of white blood cell called eosinophils. It was developed by Regeneron Pharmaceuticals and Sanofi Genzyme. It...
    22 KB (1,789 words) - 04:29, 16 July 2024
  • Thumbnail for Dexpramipexole
    first-in-class oral investigational medicine that lowers blood and tissue eosinophils before they can cause damage in the target organ. Dexpramipexole is being...
    9 KB (1,044 words) - 02:28, 17 June 2024
  • Thumbnail for Antibody-dependent cellular cytotoxicity
    antibodies. However, macrophages, neutrophils and eosinophils can also mediate ADCC, such as eosinophils killing certain parasitic worms known as helminths...
    13 KB (1,661 words) - 22:18, 9 December 2023
  • Thumbnail for Charcot–Leyden crystals
    Charcot–Leyden crystals are microscopic crystals composed of eosinophil protein galectin-10 found in people who have allergic diseases such as asthma or...
    5 KB (436 words) - 04:13, 27 April 2024
  • Thumbnail for Inflammation
    asthma, hay fever, and parasite infestation result in an increase in eosinophils, creating eosinophilia. Leukopenia can be induced by certain infections...
    97 KB (9,537 words) - 01:09, 13 September 2024
  • Thumbnail for Esophagitis
    esophagitis is caused by a high concentration of eosinophils in the esophagus. The presence of eosinophils in the esophagus may be due to an allergen and...
    16 KB (1,784 words) - 17:34, 11 August 2024
  • activation of human eosinophils. By binding to human IL-5, it blocks its biological function; consequently survival and activity of eosinophils are reduced....
    13 KB (1,383 words) - 07:59, 1 July 2024
  • Thumbnail for C-C motif chemokine ligand 24
    SA, Bickel CA, Hamilton RG, Bochner BS (June 2002). "Eotaxin-2 alters eosinophil integrin function via mitogen-activated protein kinases". Am. J. Respir...
    4 KB (612 words) - 23:46, 3 March 2023
  • Thumbnail for EGOT (gene)
    EGOT, also known as Eosinophil Granule Ontogeny (EGO)† Transcript (non-protein coding), is a human gene at 3p26.1 that produces a long noncoding RNA molecule...
    2 KB (218 words) - 01:58, 3 December 2023
  • Thumbnail for Löffler's syndrome
    Löffler's syndrome is a disease in which eosinophils accumulate in the lung in response to a parasitic infection. The parasite can be Ascaris, Strongyloides...
    9 KB (930 words) - 14:49, 15 September 2023
  • Thumbnail for Fluticasone propionate
    wide range of inhibitory effects on multiple cell types (e.g. mast cell, eosinophil, neutrophil, macrophages, and lymphocytes) and mediators (e.g. histamine...
    18 KB (1,113 words) - 19:49, 26 September 2024