FANC proteins are a network of at least 15 proteins that are associated with a cell process known as the Fanconi anemia. Fanconi anemia was first described...
9 KB (1,066 words) - 21:59, 12 May 2024
Fanconi anemia (redirect from Fanconi anemia complementation group proteins)
60% of FA is FANC-A, 16q24.3, which has later onset bone marrow failure. FA is the result of a genetic defect in a cluster of proteins responsible for...
37 KB (4,140 words) - 20:00, 18 November 2024
FANCA (category Protein pages needing a picture)
many FANC proteins have been investigated. Amongst known FANC proteins, most evidence points for a direct interaction primarily between FANCA protein and...
38 KB (4,760 words) - 00:26, 4 January 2024
BRCA2 (redirect from Brca2 protein)
One alternative symbol, FANCD1, recognizes its association with the FANC protein complex. Orthologs, styled Brca2 and Brca2, are common in other vertebrate...
72 KB (7,870 words) - 01:08, 25 September 2024
Xenopus (redirect from Xenopus proteins)
breakage syndrome, RecQL4 Rothmund-Thomson syndrome, c-Myc oncogene and FANC proteins (Fanconi anemia). Xenopus oocytes for studies of gene expression and...
52 KB (5,807 words) - 02:44, 2 August 2024
BRCA1 (redirect from BRCA1 protein)
AM, Sonoda E, Arakawa H, et al. (December 2007). "Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde". Cancer...
121 KB (13,568 words) - 14:53, 22 October 2024
FANCE (section Protein Characteristics)
complementation group E protein is a protein that in humans is encoded by the FANCE gene. The Fanconi anemia complementation group (FANC) currently includes...
18 KB (2,255 words) - 16:34, 12 June 2024
hematological deficiency has helped to reveal the contributions of the FANC protein complexes associated with the repair of double-stranded breaks in genomic...
3 KB (314 words) - 22:57, 25 November 2024
FANCD2 (category Human proteins)
FANCM, FANCN, FANCO, FANCP, FANCQ, FANCR, FANCS, FANCT, FANCU, FANCV, and probably FANCW. Fanconi anemia proteins, including FANCD2, are an emerging therapeutic...
24 KB (2,547 words) - 15:10, 19 September 2024
FANCI (category Human proteins)
known to cause Fanconi anemia. The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2...
13 KB (1,343 words) - 05:21, 6 July 2024
org. Retrieved 2022-05-11. "OMIM Entry – # 176860 – Thrombophilia Due to Protein C Deficiency, Autosomal Dominant; THPH3". omim.org. Retrieved 2018-03-01...
43 KB (995 words) - 08:29, 11 November 2024
sarcomas. The TOPBP1 gene encodes a scaffold protein which facilitates interactions between different proteins at specific times and locations. It accomplishes...
33 KB (3,762 words) - 04:21, 21 November 2024
FANCB (category Human proteins)
Fanconi anemia group B protein is a protein that in humans is encoded by the FANCB gene. The Fanconi anemia complementation group (FANC) currently includes...
8 KB (1,025 words) - 05:56, 4 January 2024
BRIP1 (category Human proteins)
through interaction with other key DNA repair proteins, specifically MLH1, BRCA1 and BLM. This group of proteins helps to ensuring genome stability, and in...
13 KB (1,537 words) - 16:59, 27 August 2024
FANCF (category Human proteins)
BRCA1, RAD51 and PCNA in foci that also contain other DNA repair proteins. All these proteins function together to facilitate DNA interstrand cross-link repair...
20 KB (2,441 words) - 21:11, 2 December 2023
the accepted method for diagnosing FA. There are currently fifteen known FANC genes, with FANCA, FANCC, FANCG, and FANCD2 being the most common. For certain...
26 KB (2,327 words) - 21:39, 20 September 2024
clinical outcomes in neuroblastomas (such as those caused by deletion of the FANC gene in Fanconi anaemia) have been linked to frequent chromothripsis occurrence...
28 KB (3,134 words) - 12:11, 11 April 2024
sparse genetic lines to label individual neurons with fluorescent proteins. The FANC dataset is currently partially proofread and annotated. The male adult...
71 KB (7,615 words) - 23:20, 18 November 2024
"Uncoupling of transcription and translation of Fanconi anemia (FANC) complex proteins during spermatogenesis". Spermatogenesis. 5 (1): e979061. doi:10...
21 KB (2,456 words) - 00:57, 27 January 2024
HLA-A), skin cancer (e.g., COL17A1, XPA, POLH), and Fanconi anemia (e.g., FANC, FANA) have been uncovered. The mutations in the donor and acceptor splice...
69 KB (6,804 words) - 04:42, 27 April 2024