Forkhead box O3, also known as FOXO3 or FOXO3a, is a human protein encoded by the FOXO3 gene. FOXO3 belongs to the O subclass of the forkhead family of...
19 KB (2,272 words) - 15:06, 17 October 2024
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
75 KB (2,848 words) - 15:25, 25 November 2024
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
12 KB (196 words) - 21:22, 24 November 2024
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
61 KB (1,739 words) - 01:11, 22 November 2024
conserved ageing-controlling pathway in evolution and among its targets are the FOXO3/Sirtuin transcription factors and the mTOR complexes, probably responsive...
96 KB (11,527 words) - 20:30, 24 November 2024
widely expressed), FOXN4 FOXO1 (widely expressed: muscle, liver, pancreas), FOXO3 (apoptosis, erythroid, longevity), FOXO4 (widely expressed), FOXO6 (liver...
8 KB (874 words) - 23:04, 18 August 2023
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
43 KB (4,655 words) - 16:05, 25 November 2024
UDP-galactose The expression of GALT is controlled by the actions of the FOXO3 gene. The absence of this enzyme results in classic galactosemia in humans...
17 KB (1,900 words) - 17:16, 8 November 2024
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
419 KB (548 words) - 03:07, 31 October 2024
2000s, he began to study the genetics of longevity, including the roles of FOXO3 and the sirtuins.: 154–155 He was awarded the Royal Society of New South...
9 KB (701 words) - 21:33, 28 December 2023
Ovarian follicle activation (section Foxo3)
timing and level of the Foxo3 expression is very important to regulate ovarian follicle activation. AKt- PTEN-AKt and Foxo3 are all involved in the same...
33 KB (4,011 words) - 09:53, 13 June 2024
involved in the regulation of transcription and stem cell fate, such as FOXO3 and EZH1. Downregulation of mitochondrial cytochrome C also reflects the...
30 KB (3,755 words) - 01:51, 4 April 2024
acquire cancer. The University of Hawaii has found that the "longevity gene" FOXO3 that reduces the effects of aging is more commonly found in individuals...
73 KB (8,531 words) - 03:17, 13 November 2024
ENSG00000150907 Forkhead Known motif – High-throughput in vitro [276] RTAAACATGTTTAC FOXO3 ENSG00000118689 Forkhead Known motif – High-throughput in vitro [277] GTAAACAW...
374 KB (81 words) - 02:10, 23 September 2023
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
118 KB (5,323 words) - 22:34, 23 November 2024
both nutraceuticals and pharmaceuticals (together or separately) such as FOXO3-activators. Researchers are also exploring ways to mitigate side-effects...
112 KB (12,378 words) - 15:55, 24 November 2024
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
7 KB (738 words) - 00:03, 15 May 2024
HGNC:1928 O00409 5818 FOXN4 HGNC:21399 Q96NZ1 5819 FOXO1 HGNC:3819 Q12778 5820 FOXO3 HGNC:3821 O43524 5821 FOXO3B HGNC:3822 A0A2Z4LIS9 5822 FOXO4 HGNC:7139 P98177...
277 KB (17 words) - 18:41, 6 October 2024
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
18 KB (845 words) - 00:23, 16 November 2024
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
325 KB (117 words) - 06:43, 18 October 2024
Forkhead family transcription factors (FoxO/FH), of which FKHR/FoxO1, FKHRL1/FoxO3 and AFX/FoxO4 are directly phosphorylated by Akt. This phosphorylation induces...
36 KB (4,072 words) - 08:10, 29 October 2024
"Auranofin displays anticancer activity against ovarian cancer cells through FOXO3 activation independent of p53". International Journal of Oncology. 45 (4):...
15 KB (1,434 words) - 15:36, 6 November 2024
increase kinase activity during autophagy, and activate ULK1. AMBRA1 promotes FOXO3 and Nazio et al. (2021) showed when AMBRA1 is reduced, there is inhibition...
14 KB (1,490 words) - 22:00, 15 June 2024
NFAT and mTOR if conditions are suitable for proliferation, or to AKT and FOXO3 under conditions of stress. Lacritin consists of 119 amino acids after cleavage...
42 KB (4,892 words) - 22:55, 17 August 2024
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
32 KB (80 words) - 17:33, 15 October 2024
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
2 KB (265 words) - 22:02, 16 February 2023
Digital immortality Eternal youth Immortality in fiction Longevity genes FOXO3 APOE CETP ACE IL6 Klotho SIRT1 TNF Related Blue zone Longevity insurance...
84 KB (91 words) - 17:39, 15 October 2024
shown that circRNA is associated with heart failure and heart disease. circFOXO3, Titin genes, circSLC8A1-1 and circAmotl1 play an important role in cardiac...
55 KB (6,557 words) - 21:55, 24 August 2024
Ageing. 2008 (approximately) It was observed that different variants of FOXO3 gene are associated with human longevity. Since then, research has been...
203 KB (18,823 words) - 03:19, 18 November 2024
modulating nuclear localization of the autophagy-related transcription factors FOXO3/FOXO3A and TFEB, suggesting that DIRAS1, along with DIRAS2, may behave as...
8 KB (1,035 words) - 00:41, 5 September 2024