Fibroblast growth factors (FGF) are a family of cell signalling proteins produced by the macrophages. They are involved in a wide variety of processes...
25 KB (3,126 words) - 10:38, 23 January 2025
This article is about the role of fibroblast growth factor signaling in mesoderm formation. Mesoderm formation is a complex developmental process involving...
10 KB (1,399 words) - 14:41, 14 July 2024
Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
24 KB (2,882 words) - 16:31, 25 October 2024
Fibroblast growth factor 8 (FGF-8) is a protein that in humans is encoded by the FGF8 gene. The protein encoded by this gene belongs to the fibroblast...
20 KB (2,446 words) - 06:03, 13 April 2025
Fibroblast growth factor receptor 1 (FGFR-1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
44 KB (5,003 words) - 14:24, 24 February 2025
specify regions of growth along the dorsal-ventral axis of the mesoderm and plays a central role in formation of the intermediate mesoderm. Vg1/Nodal signalling...
14 KB (1,553 words) - 14:36, 2 May 2024
signaling circuit than the segmented paraxial mesoderm, though also involving BMP and fibroblast growth factor signaling. Here, retinoic acid interacts with...
8 KB (791 words) - 12:20, 21 January 2024
Paracrine signaling (redirect from Paracrine factor)
similar structures: fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective...
45 KB (4,879 words) - 07:05, 7 April 2025
Angiogenesis (section Formation of tumor blood vessels)
effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord formation of bovine capillary endothelial...
50 KB (5,880 words) - 03:43, 2 November 2024
Mammary gland (section Growth)
paracrine growth factors such as epidermal growth factor (EGF), transforming growth factor beta (TGF-β), amphiregulin, fibroblast growth factor (FGF), and hepatocyte...
50 KB (5,471 words) - 13:50, 17 March 2025
Chondroblast (section Signaling, transcription and environmental factors responsible for chondroblast creation)
mesoderm. These cells, when forming from the mesoderm, specifically form from embryonic stem cells via induction through BMP4 and fibroblast growth factor...
13 KB (1,520 words) - 13:00, 17 December 2024
proliferation are Fibroblast growth factor 8 (FGF8), Wnt4, and Wnt5. Ventral developmental patterning and the expression of transcription factors is influenced...
39 KB (4,758 words) - 14:43, 3 April 2025
Myogenesis (section Specific muscle formation)
proliferate if enough fibroblast growth factor (FGF) or another growth factor is present in the medium surrounding the cells. When the growth factor runs out, the...
24 KB (2,799 words) - 10:27, 23 January 2025
different set of factors, Oct4, Sox2, Nanog, and Lin28, using a lentiviral system. Obtaining fibroblasts to produce iPSCs involves a skin biopsy, and there has...
92 KB (10,517 words) - 20:17, 8 January 2025
Omphalocele (section Environmental factors)
of fibroblast growth factor receptors 1 and 2 results in an omphalocele in mice associated with disruptions in ventral body wall muscle formation". Journal...
27 KB (3,063 words) - 17:50, 17 August 2024
positive feedback loop of fibroblast growth factors (FGFs) between the intermediate mesoderm, the lateral plate mesoderm and the surface ectoderm. FGF8...
25 KB (3,322 words) - 11:36, 28 December 2024
Colony-forming unit-fibroblast Mesenchymal stem cell / marrow stromal cell Chondrocyte Hypertrophic chondrocyte Mesenchymal (mesoderm origin) stem cells...
15 KB (1,816 words) - 13:04, 2 September 2024
Eye development (section Mesoderm)
regulated by RX/RAX transcription factor. The proteins Wnt and FGF (fibroblast growth factor) play a part in this early stage and are regulated by another protein...
16 KB (1,919 words) - 17:18, 12 July 2024
from the epidermis inhibit the formation of placodes in nearby ectoderm.[citation needed] It is believed that the mesoderm defines the pattern. The epidermis...
36 KB (4,249 words) - 00:22, 6 March 2025
Blastocyst (section Blastocyst formation)
epiblast and primitive endoderm. This process of specification known as cell fate determination is carried out in part by fibroblast growth factor (FGF)...
29 KB (3,144 words) - 03:35, 26 March 2025
Limb development (section Limb formation)
lateral plate mesoderm proliferate to the point that they cause the ectoderm above to bulge out, forming a limb bud. Fibroblast growth factor (FGF) induces...
36 KB (4,234 words) - 06:01, 28 December 2024
other transcription factors such as Emx, Otx, and Pax genes, and secreted signaling factors such as fibroblast growth factors (FGFs) and Wnts. These brain...
26 KB (3,288 words) - 21:36, 24 November 2024
nodal signaling and endoderm formation. Fibroblast growth factors (FGF), canonical Wnt pathway, bone morphogenetic protein (BMP), and retinoic acid (RA)...
37 KB (3,895 words) - 19:29, 11 March 2025
grown on a feeder layer of mouse embryonic fibroblasts and require the presence of basic fibroblast growth factor (bFGF or FGF-2). Without optimal culture...
101 KB (11,722 words) - 16:02, 12 April 2025
resulting in the halting of cell cycle and the differentiation of NPCs. Conversely, the fibroblast growth factor pathway promotes Notch signaling to keep...
95 KB (11,032 words) - 23:25, 20 February 2025
proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. Professor Marshall Urist and Professor Hari Reddi discovered...
33 KB (3,537 words) - 15:42, 19 September 2024
Sonic hedgehog protein (section Discovery and naming)
expressed in the developing embryo limbs, a morphogen called fibroblast growth factors must be secreted from the apical ectodermal ridge. Sonic hedgehog...
62 KB (7,265 words) - 13:08, 12 March 2025
Fibronectin (category Diagnostic obstetrics and gynaecology)
healing as fibroblasts don't grow well in fibrin lacking Factor XIII. Fibronectin promotes particle phagocytosis by both macrophages and fibroblasts. Collagen...
33 KB (3,689 words) - 06:14, 14 April 2025