• This article is about the role of fibroblast growth factor signaling in mesoderm formation. Mesoderm formation is a complex developmental process involving...
    10 KB (1,399 words) - 14:41, 14 July 2024
  • Fibroblast growth factors (FGF) are a family of cell signalling proteins produced by macrophages; they are involved in a wide variety of processes, most...
    25 KB (3,124 words) - 21:38, 18 August 2024
  • Thumbnail for Fibroblast growth factor receptor 1
    Fibroblast growth factor receptor 1 (FGFR-1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
    44 KB (5,003 words) - 07:11, 15 October 2024
  • Thumbnail for Paraxial mesoderm
    signaling circuit than the segmented paraxial mesoderm, though also involving BMP and fibroblast growth factor signaling. Here, retinoic acid interacts with...
    8 KB (791 words) - 12:20, 21 January 2024
  • Thumbnail for Platelet-derived growth factor
    Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
    24 KB (2,882 words) - 16:31, 25 October 2024
  • Thumbnail for Intermediate mesoderm
    specify regions of growth along the dorsal-ventral axis of the mesoderm and plays a central role in formation of the intermediate mesoderm. Vg1/Nodal signalling...
    14 KB (1,553 words) - 14:36, 2 May 2024
  • Thumbnail for Paracrine signaling
    similar structures: fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective...
    46 KB (4,967 words) - 21:12, 7 July 2024
  • Thumbnail for Omphalocele
    of fibroblast growth factor receptors 1 and 2 results in an omphalocele in mice associated with disruptions in ventral body wall muscle formation". Journal...
    27 KB (3,063 words) - 17:50, 17 August 2024
  • Thumbnail for Apical ectodermal ridge
    positive feedback loop of fibroblast growth factors (FGFs) between the intermediate mesoderm, the lateral plate mesoderm and the surface ectoderm. FGF8...
    25 KB (3,322 words) - 04:08, 11 April 2024
  • Thumbnail for Somite
    Somite (section Formation)
    primitive segments) are a set of bilaterally paired blocks of paraxial mesoderm that form in the embryonic stage of somitogenesis, along the head-to-tail...
    14 KB (1,507 words) - 09:41, 1 November 2024
  • Thumbnail for Angiogenesis
    effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord formation of bovine capillary endothelial...
    50 KB (5,887 words) - 03:43, 2 November 2024
  • Thumbnail for Eye development
    regulated by RX/RAX transcription factor. The proteins Wnt and FGF (fibroblast growth factor) play a part in this early stage and are regulated by another protein...
    16 KB (1,919 words) - 17:18, 12 July 2024
  • Thumbnail for Embryoid body
    Eswarakumar, V. P.; Seger, R.; Lonai, P. (2000). "Fibroblast growth factor (FGF) signaling through PI 3-kinase and Akt/PKB is required for embryoid body differentiation"...
    45 KB (4,513 words) - 01:22, 22 June 2024
  • Thumbnail for Induced pluripotent stem cell
    different set of factors, Oct4, Sox2, Nanog, and Lin28, using a lentiviral system. Obtaining fibroblasts to produce iPSCs involves a skin biopsy, and there has...
    92 KB (10,512 words) - 19:18, 10 October 2024
  • Thumbnail for Chondrocyte
    Colony-forming unit-fibroblast Mesenchymal stem cell / marrow stromal cell Chondrocyte Hypertrophic chondrocyte Mesenchymal (mesoderm origin) stem cells...
    15 KB (1,816 words) - 13:04, 2 September 2024
  • Thumbnail for Mammary gland
    paracrine growth factors such as epidermal growth factor (EGF), transforming growth factor beta (TGF-β), amphiregulin, fibroblast growth factor (FGF), and hepatocyte...
    50 KB (5,482 words) - 23:30, 9 December 2024
  • Thumbnail for Myogenesis
    proliferate if enough fibroblast growth factor (FGF) or another growth factor is present in the medium surrounding the cells. When the growth factor runs out, the...
    24 KB (2,738 words) - 02:09, 3 September 2024
  • Thumbnail for Chondroblast
    mesoderm. These cells, when forming from the mesoderm, specifically form from embryonic stem cells via induction through BMP4 and fibroblast growth factor...
    13 KB (1,520 words) - 13:00, 17 December 2024
  • Thumbnail for Limb development
    lateral plate mesoderm proliferate to the point that they cause the ectoderm above to bulge out, forming a limb bud. Fibroblast growth factor (FGF) induces...
    36 KB (4,233 words) - 19:13, 22 November 2024
  • Thumbnail for FGF10
    Fibroblast growth factor 10 is a protein that in humans is encoded by the FGF10 gene. The protein encoded by this gene is a member of the fibroblast growth...
    11 KB (1,338 words) - 10:26, 25 April 2024
  • Thumbnail for Primordial germ cell migration
    left and right respectively, as they actively migrate laterally across the epithelium to exit the gut, facilitated by fibroblast growth factor (FGF)...
    14 KB (1,641 words) - 03:41, 10 December 2023
  • Thumbnail for Skin
    from the epidermis inhibit the formation of placodes in nearby ectoderm.[citation needed] It is believed that the mesoderm defines the pattern. The epidermis...
    36 KB (4,247 words) - 19:35, 21 December 2024
  • Oocyte (section Formation)
    J, Slack JM (December 1994). "Spatial and temporal expression of basic fibroblast growth factor (FGF-2) mRNA and protein in early Xenopus development"...
    23 KB (2,508 words) - 10:01, 11 December 2024
  • Thumbnail for Fibronectin
    Fibronectin (category Diagnostic obstetrics and gynaecology)
    healing as fibroblasts don't grow well in fibrin lacking Factor XIII. Fibronectin promotes particle phagocytosis by both macrophages and fibroblasts. Collagen...
    33 KB (3,686 words) - 18:26, 20 December 2024
  • processes including mesoderm formation and neural tube formation. EMT has also been shown to occur in wound healing, in organ fibrosis and in the initiation...
    59 KB (6,836 words) - 03:14, 26 August 2024
  • Thumbnail for Sonic hedgehog protein
    expressed in the developing embryo limbs, a morphogen called fibroblast growth factors must be secreted from the apical ectodermal ridge. Sonic hedgehog...
    62 KB (7,249 words) - 20:50, 23 September 2024
  • conditional specification. The endoderm sends a fibroblast growth factor (FGF) signal to specify the notocord and the mesenchyme fates. Anterior cells respond...
    33 KB (5,170 words) - 20:53, 16 September 2024
  • Thumbnail for Endothelial stem cell
    becoming an EC. In addition, basic fibroblast growth factor FGF-2 is also involved in promoting angioblasts from the mesoderm. After angioblasts commit to becoming...
    26 KB (3,444 words) - 20:02, 18 May 2024
  • Thumbnail for Cellular differentiation
    development, and include bone morphogenetic proteins, transforming growth factors (TGFs), and fibroblast growth factors (FGFs). TGFs and FGFs have been...
    50 KB (6,030 words) - 16:44, 2 October 2024
  • Thumbnail for Germ cell
    away from the endoderm and into the mesoderm. After splitting into two populations, the germ cells continue migrating laterally and in parallel until they...
    31 KB (4,039 words) - 06:54, 12 December 2024