• Thumbnail for Gelsolin
    Gelsolin is an actin-binding protein that is a key regulator of actin filament assembly and disassembly. Gelsolin is one of the most potent members of...
    14 KB (1,645 words) - 10:13, 4 January 2024
  • Thumbnail for Plasma gelsolin
    Plasma gelsolin (pGSN) is an 83 kDa abundant protein constituent of normal plasma and an important component of the innate immune system. The identification...
    95 KB (9,144 words) - 08:16, 1 September 2024
  • Thumbnail for Thomas P. Stossel
    hematologist, inventor, medical researcher, and writer, who discovered gelsolin and invented the BioAegis technology estate. He was also a professor emeritus...
    11 KB (1,210 words) - 16:39, 2 August 2024
  • Thumbnail for Familial Amyloidosis, Finnish Type
    Familial Amyloidosis, Finnish Type (FAF), also called hereditary gelsolin amyloidosis and AGel amyloidosis (AGel), is an amyloid condition with a number...
    8 KB (722 words) - 23:14, 3 November 2023
  • transthyretin (ATTR, the most commonly implicated protein), apolipoprotein A1, and gelsolin. Due to the rareness of the other types of familial neuropathies, transthyretin...
    6 KB (505 words) - 14:56, 27 October 2023
  • Thumbnail for Lattice corneal dystrophy
    associated with manifestations of systemic amyloidosis due to accumulation of gelsolin. Associated conditions may include cutis laxa and ataxia. type III is also...
    8 KB (849 words) - 23:18, 20 September 2022
  • Thumbnail for Macrophage-capping protein
    humans is encoded by the CAPG gene. This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly...
    5 KB (617 words) - 18:11, 24 October 2023
  • railway station in Watford, Hertfordshire (by National Rail station code) Gelsolin Gigabyte System Network, a computer networking technology Global SchoolNet...
    666 bytes (110 words) - 17:40, 25 June 2024
  • Thumbnail for Listeria
    manner and aids the bacterial migration to the host cell's outer membrane. Gelsolin, an actin filament severing protein, localizes at the tail of Listeria...
    59 KB (6,191 words) - 19:46, 30 September 2024
  • Thumbnail for Cerebral amyloid angiopathy
    mutations in ITM2B. Familial amyloidosis-Finnish type is associated with gelsolin amyloid (AGel). CAA is associated with brain hemorrhages, particularly...
    18 KB (1,768 words) - 14:27, 21 August 2024
  • Thumbnail for Villin-1
    border. Villin-1 is encoded by the VIL1 gene. Villin-1 contains multiple gelsolin-like domains capped by a small (8.5 kDa) "headpiece" at the C-terminus...
    9 KB (1,108 words) - 08:33, 17 October 2022
  • Thumbnail for Microfilament
    such as Capping Protein and CapG, etc. Filament-severing proteins like gelsolin. Actin depolymerizing proteins such as ADF/cofilin. The actin filament...
    21 KB (2,785 words) - 17:16, 15 June 2024
  • cells by disrupting the actin network. Latrunculin A: Target and functions Gelsolin - Latrunculin A causes end- blocking; this protein binds to the barbed...
    20 KB (2,170 words) - 12:44, 26 September 2024
  • Thumbnail for Cytoskeleton
    T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors Cofilin 1 2 Destrin Gelsolin Profilin 1 2 Titin...
    45 KB (5,121 words) - 06:34, 27 May 2024
  • Thumbnail for Beta-actin
    DICTYOSTELIUM CAATP-ACTIN IN COMPLEX WITH GELSOLIN SEGMENT 1 1c0g: CRYSTAL STRUCTURE OF 1:1 COMPLEX BETWEEN GELSOLIN SEGMENT 1 AND A DICTYOSTELIUM/TETRAHYMENA...
    8 KB (997 words) - 22:28, 15 April 2024
  • Ardalan–Shoja–Kiuru syndrome is a clinical syndrome featuring hereditary gelsolin amyloidosis and retinitis pigmentosa. This syndrome was first recognized...
    3 KB (238 words) - 18:21, 27 October 2023
  • Thumbnail for Troponin I
    T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors Cofilin 1 2 Destrin Gelsolin Profilin 1 2 Titin...
    18 KB (2,156 words) - 03:32, 22 July 2024
  • Thumbnail for FLII
    humans is encoded by the FLII gene. This gene encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein...
    9 KB (1,051 words) - 23:15, 7 August 2023
  • Thumbnail for Lipid-anchored protein
    myristoylated and involved in the regulation of apoptosis are actin and gelsolin. S-palmitoylation (i.e. attachment of palmitic acid) is a reversible protein...
    20 KB (2,232 words) - 07:44, 22 June 2024
  • Thumbnail for F-actin capping protein
    end), thereby blocking the exchange of subunits at these ends. Unlike gelsolin and severin this protein does not sever actin filaments. The F-actin capping...
    3 KB (257 words) - 02:10, 29 November 2023
  • Thumbnail for Asgard (archaea)
    archaeons have a regulated actin cytoskeleton, and the profilins and gelsolins they use can interact with eukaryotic actins. In addition, Asgard archaea...
    33 KB (2,842 words) - 17:39, 29 July 2024
  • Thumbnail for Keratin
    T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors Cofilin 1 2 Destrin Gelsolin Profilin 1 2 Titin...
    39 KB (3,017 words) - 13:44, 1 September 2024
  • Calbindin Calmodulin CALM1 CALM2 CALM3 CALML3 CALML5 Calsequestrin Calretinin Gelsolin Neuronal calcium sensors Calsenilin Frequenin GUCA 1A 1B Hippocalcin Neurocalcin...
    19 KB (2,056 words) - 16:29, 7 September 2024
  • variants Kidney S H AApoCIII Apolipoprotein C III, variants Kidney S H AGel Gelsolin, variants Kidney, PNS, cornea S H ALys Lysozyme, variants Kidney S H ALECT2...
    55 KB (5,426 words) - 12:05, 18 September 2024
  • Thumbnail for Microtubule
    T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors Cofilin 1 2 Destrin Gelsolin Profilin 1 2 Titin...
    64 KB (7,838 words) - 19:01, 10 September 2024
  • Thumbnail for Actin
    it to break. Gelsolin inserts itself between actin molecules in a filament, disrupting the filament. After the filament breaks, gelsolin remains attached...
    153 KB (18,278 words) - 03:30, 28 September 2024
  • Thumbnail for Androgen receptor
    protein 6, L-DOPA, EFCAB6, Epidermal growth factor receptor, FOXO1, GAPDH, Gelsolin, GNB2L1, GSK3B, HDAC1, HSP90AA1, HTATIP, MAGEA11, MED1, MYST2, NCOA1, NCOA2...
    87 KB (9,376 words) - 13:18, 19 August 2024
  • Thumbnail for Myristoylation
    where it prompts the release of cytochrome c leading to cell death. Actin, gelsolin and p21-activated kinase 2 PAK2 are three other proteins that are myristoylated...
    23 KB (2,277 words) - 18:23, 3 June 2024
  • Thumbnail for ACTA2
    DICTYOSTELIUM CAATP-ACTIN IN COMPLEX WITH GELSOLIN SEGMENT 1 1c0g: CRYSTAL STRUCTURE OF 1:1 COMPLEX BETWEEN GELSOLIN SEGMENT 1 AND A DICTYOSTELIUM/TETRAHYMENA...
    9 KB (1,136 words) - 03:07, 6 May 2024
  • Thumbnail for Phosphatidylinositol 4,5-bisphosphate
    Yamamoto, Masaya; Mejillano, Marisan; Yin, Helen (November 19, 1999). "Gelsolin, a Multifunctional Actin Regulatory Protein". The Journal of Biological...
    21 KB (2,099 words) - 13:43, 21 August 2024