• Thumbnail for Gephyrin
    Gephyrin is a protein that in humans is encoded by the GPHN gene. This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter...
    20 KB (2,486 words) - 06:40, 31 March 2024
  • Thumbnail for Hyperekplexia
    microtubule structures. Gephyrin also assists in clustering GABA receptors at synapses and molybdenum cofactor synthesis. Because of gephyrin's multi-functional...
    18 KB (1,986 words) - 20:07, 8 October 2024
  • Thumbnail for Glycine receptor
    competitive antagonist of GlyR. Cannabinoids enhance the function. The protein Gephyrin has been shown to be necessary for GlyR clustering at inhibitory synapses...
    14 KB (1,546 words) - 19:55, 4 March 2024
  • Templeton and a team of researchers looked at mutations encompassing the gephyrin gene of chromosome 14 and were able to trace the split back to the last...
    6 KB (429 words) - 17:36, 14 November 2024
  • Thumbnail for Palmitoylation
    localizations that are involved in memory formation. Palmitoylation of gephyrin has been reported to influence GABAergic synapses. DHHC domain Myristoylation...
    15 KB (1,591 words) - 05:03, 19 October 2024
  • Thumbnail for Stiff-person syndrome
    GABA-receptor-associated protein (GABARAP). Autoantibodies against amphiphysin and gephyrin are also sometimes found in SPS patients. The antibodies appear to interact...
    27 KB (2,949 words) - 01:40, 29 October 2024
  • identified as a regulator of the localization of gephyrin, inducing the formation of submembrane gephyrin aggregates that accumulate glycine and GABA receptors...
    3 KB (331 words) - 00:15, 28 July 2024
  • Thumbnail for Dorsal root ganglion
    Carbonetto S, Wiseman PW, Ribeiro-da-Silva A, De Koninck Y (June 2014). "Gephyrin Clusters Are Absent from Small Diameter Primary Afferent Terminals Despite...
    9 KB (1,019 words) - 15:07, 2 May 2024
  • Thumbnail for Gate control theory
    Carbonetto S, Wiseman PW, Ribeiro-da-Silva A, De Koninck Y (June 2014). "Gephyrin Clusters Are Absent from Small Diameter Primary Afferent Terminals Despite...
    17 KB (1,903 words) - 15:52, 27 August 2024
  • Thumbnail for Alpha cell
    al., 2017 find artemisinin itself forces α⇨β conversion in rodents (via gephyrin) and zebrafish while Ackermann et al., 2018 find artesunate does not and...
    38 KB (3,972 words) - 06:49, 3 March 2024
  • Thumbnail for Molybdenum
    Buchmeier, S.; Meier, J. C.; Schwarz, G. (2008). "Splice-specific Functions of Gephyrin in Molybdenum Cofactor Biosynthesis". Journal of Biological Chemistry....
    75 KB (8,582 words) - 11:32, 2 November 2024
  • Thumbnail for GABAA receptor
    burnout. 4-Iodopropofol GABA receptor GABAB receptor GABAA-ρ receptor Gephyrin Glycine receptor GABAA receptor positive allosteric modulators GABAA receptor...
    55 KB (5,958 words) - 06:23, 11 November 2024
  • Thumbnail for Neuroligin
    synaptic proteins in the post-synaptic density of excitatory synapses, and gephyrin, the respective scaffolding protein of inhibitory post-synapses. In addition...
    23 KB (2,644 words) - 20:28, 21 November 2024
  • surface glycine receptors by gephyrin » Nat Neurosci, 4 (3), 2001, 253-260 J. Kirsch, I. Wolters, A. Triller, H. Betz, « Gephyrin Antisense Oligonucleotides...
    9 KB (1,047 words) - 07:19, 23 June 2024
  • Thumbnail for GABAA receptor positive allosteric modulator
    Fig 4. GABAergic synapse. The synaptic anchoring protein Gephyrin is indirectly linked to the GABAA receptors....
    33 KB (3,698 words) - 22:10, 6 November 2024
  • Thumbnail for ARHGEF9
    newly identified brain-specific GEF, induces submembrane clustering of gephyrin". Nat. Neurosci. 3 (1): 22–9. doi:10.1038/71096. PMID 10607391. S2CID 24878249...
    4 KB (510 words) - 00:17, 28 July 2024
  • Thumbnail for MTOR
    Barrow RK, Blackshaw S, et al. (May 1999). "Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling". Science. 284 (5417): 1161–4...
    119 KB (12,661 words) - 15:12, 8 November 2024
  • Thumbnail for NRXN1
    gamma-aminobutyric acid receptor clustering neuronal signal transduction gephyrin clustering involved in postsynaptic density assembly postsynaptic density...
    11 KB (1,321 words) - 15:55, 7 July 2023
  • Thumbnail for Eukaryotic translation elongation factor 1 alpha 1
    number and size of inhibitory postsynaptic complexes like postsynaptic gephyrin clusters. eEF1A has also been found to bind to several kinases, phospholipases...
    22 KB (2,672 words) - 20:37, 3 December 2023
  • Thumbnail for Daniel Choquet
    (2001). "Fast and reversible trapping of surface glycine receptors by gephyrin". Nature Neuroscience. 4 (3): 253–260. doi:10.1038/85099. PMID 11224541...
    9 KB (815 words) - 01:00, 30 October 2024
  • Thumbnail for Dystroglycan
    AG, Wang F, St-Louis M, Carbonetto S, Wiseman PW, et al. (June 2014). "Gephyrin clusters are absent from small diameter primary afferent terminals despite...
    14 KB (1,615 words) - 11:38, 15 November 2024
  • Thumbnail for Molybdenum in biology
    Buchmeier, S.; Meier, J. C.; Schwarz, G. (2008). "Splice-specific Functions of Gephyrin in Molybdenum Cofactor Biosynthesis". Journal of Biological Chemistry....
    22 KB (2,343 words) - 11:31, 2 November 2024
  • Thumbnail for Derlin-2
    (2006). "Neuronal cotransport of glycine receptor and the scaffold protein gephyrin". J. Cell Biol. 172 (3): 441–51. doi:10.1083/jcb.200506066. PMC 2063653...
    4 KB (472 words) - 06:53, 28 March 2024
  • biosynthesis, molybendum is incorporated to MPT by the two-domain protein gephyrin. MPT synthase sulfurylase recharges MPT synthase with a sulfur atom after...
    11 KB (1,305 words) - 11:31, 2 November 2024
  • Thumbnail for GABARAP
    acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse". Proceedings...
    13 KB (1,678 words) - 20:34, 13 October 2022
  • A crosstalk between β1 and β3 integrins controls glycine receptor and gephyrin trafficking at synapses. Nature neuroscience, 13(11), 1388–1395. Charrier...
    6 KB (598 words) - 15:10, 23 June 2024
  • Thumbnail for ENAH (gene)
    Imamura H, Takahashi K, et al. (February 1998). "Interactions of drebrin and gephyrin with profilin". Biochemical and Biophysical Research Communications. 243...
    10 KB (1,100 words) - 02:39, 29 March 2024
  • Thumbnail for DBN1
    Mammoto A, Sasaki T, Asakura T, et al. (1998). "Interactions of drebrin and gephyrin with profilin". Biochem. Biophys. Res. Commun. 243 (1): 86–9. doi:10.1006/bbrc...
    7 KB (892 words) - 11:37, 15 November 2024
  • Thumbnail for NRXN2
    Biological process neuron cell-cell adhesion cell adhesion signal transduction gephyrin clustering involved in postsynaptic density assembly postsynaptic density...
    7 KB (766 words) - 00:36, 4 March 2023
  • Thumbnail for GLRB
    beta". Meyer G, Kirsch J, Betz H, Langosch D (1995). "Identification of a gephyrin binding motif on the glycine receptor beta subunit". Neuron. 15 (3): 563–72...
    5 KB (550 words) - 07:49, 6 January 2024