Glycosaminoglycans (GAGs) or mucopolysaccharides are long, linear polysaccharides consisting of repeating disaccharide units (i.e. two-sugar units). The...
23 KB (2,639 words) - 09:17, 29 July 2024
Polysulfated glycosaminoglycan (PSGAG), sold under the brand name Adequan, is an injectable drug for dogs and horses that is used to alleviate the limpness...
14 KB (1,148 words) - 18:01, 27 February 2023
enzymology, a glycosaminoglycan galactosyltransferase (EC 2.4.1.74) is an enzyme that catalyzes the chemical reaction UDP-galactose + glycosaminoglycan ⇌ {\displaystyle...
2 KB (133 words) - 14:23, 26 August 2023
covalently attached glycosaminoglycan (GAG) chain(s). The point of attachment is a serine (Ser) residue to which the glycosaminoglycan is joined through...
8 KB (835 words) - 16:01, 3 December 2023
Sodium hyaluronate (category Glycosaminoglycans)
glycosaminoglycan found in various connective tissue of humans. Sodium hyaluronate is the sodium salt of hyaluronic acid. It is a glycosaminoglycan and...
17 KB (1,839 words) - 11:28, 15 August 2024
Iduronidase (redirect from Glycosaminoglycan alpha-L-iduronohydrolase)
laronidase), sold as Aldurazyme, is an enzyme with the systematic name glycosaminoglycan α-L-iduronohydrolase. It catalyses the hydrolysis of unsulfated α-L-iduronosidic...
17 KB (1,583 words) - 10:00, 1 September 2024
Sulodexide (category Glycosaminoglycans)
Sulodexide, traded as Aterina, is a highly purified mixture of glycosaminoglycans composed of heparan sulfate (80%) and dermatan sulfate (20%). The low...
6 KB (583 words) - 22:58, 2 January 2024
Hyaluronic acid (category Glycosaminoglycans)
nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans as it is non-sulfated...
51 KB (5,575 words) - 02:49, 13 September 2024
with how the body breaks down certain large sugar molecules called glycosaminoglycans (also known as GAGs or mucopolysaccharides). In children with this...
46 KB (5,317 words) - 18:53, 10 September 2024
increased amount of protein and mucopolysaccharides. These can include glycosaminoglycans, such as hyaluronic acid, chondroitin sulfate and other mucopolysaccharides...
10 KB (924 words) - 19:17, 25 July 2024
Heparin (category Glycosaminoglycans)
unfractionated heparin (UFH), is a medication and naturally occurring glycosaminoglycan. Heparin is a blood anticoagulant that increases the activity of antithrombin...
77 KB (7,855 words) - 18:45, 29 August 2024
related to the concentration of proteoglycan aggregates and charged glycosaminoglycan side chains in articular cartilage. In the complex of Gd3+ and DTPA5−...
9 KB (698 words) - 06:00, 13 July 2024
antioxidant and anti-inflammatory effects, stimulation of collagen and glycosaminoglycan synthesis in skin fibroblasts and promotion of blood vessels growth...
19 KB (2,260 words) - 21:50, 2 March 2024
Gene ontology Molecular function glycosaminoglycan binding calcium ion binding Cellular component extracellular region basement membrane cell junction...
11 KB (1,298 words) - 19:18, 12 April 2024
kDa to which three long chains (each approximately 70-100 kDa) of glycosaminoglycans (often heparan sulfate, HS, but can be chondroitin sulfate, CS) are...
84 KB (11,012 words) - 18:25, 12 September 2024
Heparan sulfate (category Glycosaminoglycans)
are the main HS-bearing species. Heparan sulfate is a member of the glycosaminoglycan (GAG) family of carbohydrates and is very closely related in structure...
36 KB (4,151 words) - 06:37, 27 May 2024
Chondroitin sulfate (category Glycosaminoglycans)
Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) composed of a chain of alternating sugars (N-acetylgalactosamine and glucuronic acid). It is...
36 KB (4,168 words) - 17:45, 26 August 2024
Versican (section Glycosaminoglycan binding region)
proteoglycans share a homologous globular N-terminal, C-terminal, and glycosaminoglycan (GAG) binding regions. The N-terminal (G1) globular domain consists...
19 KB (2,427 words) - 15:21, 24 January 2024
Enzymes in the Golgi append proteins to glycosaminoglycans, thus creating proteoglycans. Glycosaminoglycans are long unbranched polysaccharide molecules...
25 KB (2,765 words) - 14:39, 26 July 2024
tension on the tissue. It has a low content of glycosaminoglycans (2% of dry weight). Glycosaminoglycans are long, unbranched polysaccharides (relatively...
12 KB (1,563 words) - 15:52, 2 April 2024
(a type of collagen), a network of collagen type II fibrils with glycosaminoglycan, hyaluronan, opticin, and a wide array of proteins. Despite having...
18 KB (1,744 words) - 03:14, 27 May 2024
patched binding peptidase activity zinc ion binding laminin-1 binding glycosaminoglycan binding morphogen activity hydrolase activity protein binding endopeptidase...
62 KB (7,249 words) - 04:46, 3 August 2024
levels in patients with different types of diseases". Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A. Progress in Molecular...
121 KB (12,789 words) - 20:47, 6 September 2024
the penis. Urethral glands produce a colloid secretion containing glycosaminoglycans; this secretion protects the epithelium against urine. Untreated urethritis...
2 KB (134 words) - 09:38, 18 July 2023
clinical anticoagulant worldwide. Heparin is a naturally occurring glycosaminoglycan. There are three major categories of heparin: unfractionated heparin...
78 KB (8,755 words) - 00:46, 23 July 2024
engineering and regenerative medicine applications as they resemble animal glycosaminoglycans (GAGs). They are used for tissue engineering, wound coverage, and...
27 KB (2,656 words) - 03:24, 18 August 2024
by binding to hyaluronan. Attached to each aggrecan molecule are glycosaminoglycan (GAG) chains of chondroitin sulfate and keratan sulfate. Increasing...
16 KB (1,791 words) - 18:11, 4 August 2024
cells. This layer contains heparan sulfate, a negatively charged glycosaminoglycan that contributes to the electrostatic barrier of the glomerular filter...
5 KB (579 words) - 05:55, 22 August 2024
Dermatan sulfate (category Glycosaminoglycans)
Dermatan sulfate is a glycosaminoglycan (formerly called a mucopolysaccharide) found mostly in skin, but also in blood vessels, heart valves, tendons...
4 KB (334 words) - 07:07, 2 September 2023
bundles in the fibrosa. This is due to an excess of dermatan sulfate, a glycosaminoglycan. This weakens the leaflets and adjacent tissue, resulting in increased...
55 KB (5,580 words) - 08:35, 19 February 2024