• In chemistry, hydroxylation can refer to: (i) most commonly, hydroxylation describes a chemical process that introduces a hydroxyl group (−OH) into an...
    9 KB (1,058 words) - 07:42, 20 June 2024
  • Thumbnail for Phenylacetone
     ... The location of the p-hydroxylation and β-hydroxylation reactions is important in species where aromatic hydroxylation of amphetamine is the predominant...
    8 KB (1,749 words) - 16:49, 28 April 2024
  • The Woodward cis-hydroxylation (also known as the Woodward reaction) is the chemical reaction of alkenes with iodine and silver acetate in wet acetic...
    2 KB (202 words) - 06:01, 28 December 2023
  • Thumbnail for Lisdexamfetamine
     ... The location of the p-hydroxylation and β-hydroxylation reactions is important in species where aromatic hydroxylation of amphetamine is the predominant...
    45 KB (14,144 words) - 09:47, 21 August 2024
  • Thumbnail for Oxaziridine
    reagents in organic chemistry for a variety of oxidations, including alpha hydroxylation of enolates, epoxidation and aziridination of olefins, and other heteroatom...
    25 KB (2,506 words) - 19:06, 6 April 2024
  • Thumbnail for Hydroxylation of estradiol
    The hydroxylation of estradiol is one of the major routes of metabolism of the estrogen steroid hormone estradiol. It is hydroxylated into the catechol...
    14 KB (1,786 words) - 11:40, 10 March 2023
  • Thumbnail for Cytochrome P450
    fatty acids, xenobiotics, and participate in many biosyntheses. By hydroxylation, CYP450 enzymes convert xenobiotics into hydrophilic derivatives, which...
    15 KB (1,669 words) - 21:07, 28 May 2024
  • benzene, such as halogenation, cyanation, trifluoromethylation, and hydroxylation. The reaction was discovered in 1884 by Swiss chemist Traugott Sandmeyer...
    16 KB (1,738 words) - 05:14, 17 August 2024
  • Thumbnail for Phenylpropanolamine
     ... The location of the p-hydroxylation and β-hydroxylation reactions is important in species where aromatic hydroxylation of amphetamine is the predominant...
    51 KB (5,502 words) - 23:47, 3 August 2024
  • The Milas hydroxylation is an organic reaction converting an alkene to a vicinal diol, and was developed by Nicholas A. Milas in the 1930s. The cis-diol...
    6 KB (698 words) - 17:41, 11 February 2023
  • Thumbnail for P-Hydroxynorephedrine
    to one patient indicates that the hydroxylation occurs in body tissues. ... a major portion of the β-hydroxylation of hydroxyamphetamine occurs in non-adrenal...
    3 KB (1,230 words) - 16:47, 28 April 2024
  • Thumbnail for Collagen
    this vitamin results in impaired collagen synthesis and scurvy. These hydroxylation reactions are catalyzed by two different enzymes: prolyl 4-hydroxylase...
    70 KB (7,693 words) - 15:43, 20 July 2024
  • Thumbnail for Aldosterone synthase
    The enzyme catalyzes sequential hydroxylations of the steroid angular methyl group at C18 after initial 11β-hydroxylation (the enzyme has steroid 18-hydroxylase...
    21 KB (2,347 words) - 00:25, 10 July 2024
  • Thumbnail for Hydroxyproline
    group attached to the gamma carbon atom. Hydroxyproline is produced by hydroxylation of the amino acid proline by the enzyme prolyl hydroxylase following...
    10 KB (935 words) - 03:37, 10 June 2024
  • Thumbnail for Alcohol (chemistry)
    alcohols are produced by hydroxylation, i.e., the installation of a hydroxy group using oxygen or a related oxidant. Hydroxylation is the means by which...
    34 KB (3,818 words) - 08:17, 6 August 2024
  • Thumbnail for 4-Hydroxyamphetamine
     ... The location of the p-hydroxylation and β-hydroxylation reactions is important in species where aromatic hydroxylation of amphetamine is the predominant...
    10 KB (1,995 words) - 16:47, 28 April 2024
  • Thumbnail for Methocarbamol
    is not hydrolyzed metabolically; its metabolism is by Phase I ring hydroxylation and O-demethylation, followed by Phase II conjugation. All the major...
    26 KB (2,349 words) - 14:19, 31 March 2024
  • Thumbnail for 4-Hydroxyphenylacetone
     ... The location of the p-hydroxylation and β-hydroxylation reactions is important in species where aromatic hydroxylation of amphetamine is the predominant...
    2 KB (1,191 words) - 16:48, 28 April 2024
  • Thumbnail for Phenylalanine
    (1983-03-14). "Stereospecificity of phenylalanine plasma kinetics and hydroxylation in man following oral application of a stable isotope-labelled pseudo-racemic...
    28 KB (2,386 words) - 21:26, 25 July 2024
  • Thumbnail for Corticosteroid
    corticosterone). These enzymes are nearly identical (they share 11β-hydroxylation and 18-hydroxylation functions), but aldosterone synthase is also able to perform...
    41 KB (4,147 words) - 01:54, 20 July 2024
  • Thumbnail for Methanol
    A. Friesner; Stephen J. Lippard (2003). "Mechanistic Studies on the Hydroxylation of Methane by Methane Monooxygenase". Chem. Rev. 103 (6): 2385–2420...
    55 KB (5,310 words) - 23:22, 18 August 2024
  • Thumbnail for Trazodone
    Trazodone is known to be extensively metabolized by the liver via hydroxylation, N-oxidation, and N-dealkylation. Several metabolites of trazodone have...
    105 KB (10,015 words) - 11:24, 16 August 2024
  • Thumbnail for Methoxsalen
    This is then followed by a hydroxylation catalyzed by the enzyme marmesin synthase to yield marmesin. Another hydroxylation is catalyzed by psoralen synthase...
    10 KB (748 words) - 07:15, 14 March 2024
  • Thumbnail for Norethisterone
    metabolism.[citation needed] Norethisterone is partially metabolized via hydroxylation by CYP3A4, and inhibitors and inducers of CYP3A4 can significantly alter...
    92 KB (9,328 words) - 04:45, 11 July 2024
  • Thumbnail for Metoprolol
    intestines. Metoprolol undergoes extensive metabolism in the liver, mainly α-hydroxylation and O-demethylation through various cytochrome P450 enzymes such as...
    31 KB (2,605 words) - 23:47, 9 July 2024
  • Thumbnail for Methamphetamine
    The main metabolic pathways involve aromatic para-hydroxylation, aliphatic alpha- and beta-hydroxylation, N-oxidation, N-dealkylation, and deamination. The...
    151 KB (14,850 words) - 16:49, 21 August 2024
  • Thumbnail for Vitamin D
    synthesis, is biologically inactive. It is activated by two protein enzyme hydroxylation steps, the first in the liver and the second in the kidneys. Because...
    162 KB (17,765 words) - 17:56, 20 August 2024
  • Thumbnail for Metandienone
    testosterone and 2% of that of DHT. The drug is metabolized in the liver by 6β-hydroxylation, 3α- and 3β-oxidation, 5β-reduction, 17-epimerization, and conjugation...
    27 KB (2,274 words) - 02:54, 22 March 2024
  • Thumbnail for Alfacalcidol
    impaired renal function alters the ability to carry out the second hydroxylation step required for the formation of the physiologically active form of...
    7 KB (456 words) - 05:04, 13 December 2023
  • the precursor of glycine and cysteine. Tyrosine is synthesized by the hydroxylation of phenylalanine, which is an essential amino acid. Estimating the daily...
    27 KB (2,690 words) - 16:06, 13 May 2024