• Loop extrusion is a major mechanism of Nuclear organization. It is a dynamic process in which structural maintenance of chromosomes (SMC) protein complexes...
    38 KB (4,377 words) - 07:31, 7 December 2024
  • Thumbnail for Cohesin
    process of loop extrusion, cohesin moves actively along the two DNA double helices, translocating one of them with respect to the other. Thus, the loop can become...
    60 KB (6,745 words) - 05:50, 17 December 2024
  • Thumbnail for Topologically associating domain
    simulations have shown that chromatin loop extrusion driven by cohesin motors can generate TADs. In the loop extrusion model, cohesin binds chromatin, pulls...
    32 KB (3,426 words) - 03:04, 18 November 2024
  • Thumbnail for Nuclear organization
    breathing. At intermediate scales, an active process of loop extrusion creates dynamic loops and Topologically Associating Domains (TADs). Each human...
    32 KB (3,819 words) - 04:21, 16 December 2024
  • Chromatin (section DNA loops)
    with loops forming and disappearing. The loops are regulated by two main elements: Cohesins, protein complexes that generate loops by extrusion of the...
    53 KB (5,924 words) - 21:12, 17 December 2024
  • Thumbnail for Fused filament fabrication
    feedback loop. This is similar to ambient heating of a room. FFF and the other technologies of additive manufacturing by material extrusion (EAM) techniques...
    46 KB (4,623 words) - 23:21, 4 January 2025
  • Thumbnail for Condensin
    to translocate along dsDNA (motor activity) and to "extrude" DNA loops (loop extrusion activity) in an ATP hydrolysis-dependent manner. In the latter experiments...
    66 KB (7,622 words) - 11:51, 20 August 2024
  • Thumbnail for Nucleoid
    SMC complexes from different organisms differ in the mechanism of loop extrusion. Single molecule fluorescence microscopy of MukBEF in E. coli suggests...
    151 KB (17,185 words) - 06:38, 8 August 2024
  • Thumbnail for Cornelia de Lange syndrome
    de Lange syndrome mutations in NIPBL can impair cohesin-mediated DNA loop extrusion". PNAS. 119 (18): e2201029119. Bibcode:2022PNAS..11901029P. doi:10.1073/pnas...
    27 KB (3,107 words) - 01:35, 5 January 2025
  • Ganji et al for their publication entitled 'Real-time imaging of DNA loop extrusion by condensin' appeared in Science in 2018. "Home - Kavli Institute of...
    4 KB (451 words) - 09:02, 6 September 2023
  • Thumbnail for Cees Dekker
    DNA loop-extrusion by SMC proteins 2019, first visualization of the circular chromosome of E coli bacteria. 2020s 2020, discovered a new type of loops in...
    18 KB (1,938 words) - 15:46, 26 August 2024
  • Thumbnail for Rubber band
    Rubber band (redirect from Snoopy loop)
    A rubber band (also known as an elastic, gum band or lacky band) is a loop of rubber, usually ring or oval shaped, and commonly used to hold multiple objects...
    24 KB (2,511 words) - 17:30, 29 October 2024
  • Thumbnail for Kim Nasmyth
    Kim Nasmyth explaining loop extrusion with a climbing rope...
    19 KB (1,578 words) - 07:17, 17 November 2024
  • Thumbnail for CTCF
    chromatin structure. It is currently believed that the DNA loops are formed by the loop extrusion mechanism, whereby the cohesin ring is actively being translocated...
    26 KB (3,172 words) - 16:20, 28 November 2024
  • Thumbnail for STAG2
    STAG2 has been shown to interact with STAG1. Cohesion folds by DNA loop extrusion and this cohesion consists of SMC1, SMC3, RAD21, and either STAG1 or...
    8 KB (1,014 words) - 05:06, 1 December 2023
  • critical regulator of IgH locus contraction that facilitates chromatin loop extrusion across the entire locus. He is a member of the editorial board for Immunity...
    11 KB (1,031 words) - 01:10, 26 October 2024
  • Thumbnail for O-ring
    cross-sectional diameter, and radial clearance. O-rings can be produced by extrusion, injection molding, pressure molding or transfer molding. The first patent...
    26 KB (3,361 words) - 14:13, 15 June 2024
  • Thumbnail for Cruciform DNA
    range of cellular proteins were characterized. The mechanism of cruciform extrusion occurs through the opening of double stranded DNA to allow for intrastrand...
    28 KB (3,447 words) - 16:00, 30 March 2024
  • Thumbnail for Hi-C (genomic analysis technique)
    property of underlying biological mechanisms, which defines TADs as loop extrusions, compartmentalizations, or any dynamic genomic pattern rather than...
    98 KB (10,972 words) - 12:56, 11 June 2024
  • Thumbnail for 3D printing processes
    of physical transformations which are used in 3D printing include melt extrusion, light polymerization, continuous liquid interface production and sintering...
    76 KB (8,369 words) - 00:11, 12 December 2024
  • Thumbnail for Heat pipe
    Heat pipe (section Loop)
    (VCHP) for spacecraft thermal control. The heat pipe is an aluminium extrusion, similar to that shown in the first figure. The bottom flanged area is...
    59 KB (7,644 words) - 05:19, 18 December 2024
  • Thumbnail for 3D printing
    models—is fused deposition modeling, a special application of plastic extrusion, developed in 1988 by S. Scott Crump and commercialized by his company...
    209 KB (21,845 words) - 23:18, 4 January 2025
  • standard thermoplastic processing methods, such as injection molding and extrusion. Coprocessing with other polymers can include coextrusion, molding, and...
    14 KB (1,783 words) - 16:13, 19 November 2024
  • Thumbnail for Polypropylene
    Melting process of polypropylene can be achieved via extrusion and molding. Common extrusion methods include production of melt-blown and spun-bond...
    50 KB (5,823 words) - 13:26, 2 December 2024
  • Thumbnail for Slip bands in metals
    dislocation loops at the surface cause the irreversible/persistent surface step associated with slip-bands. Surface relief through extrusion occurs on the...
    51 KB (5,228 words) - 18:51, 16 May 2024
  • Thumbnail for District heating
    District heating (redirect from Steam loop)
    egyr.2021.08.161. ISSN 2352-4847. S2CID 240180109. Doyle, Lucía (2021). "Extrusion foaming behavior of polybutene-1. Toward single-material multifunctional...
    132 KB (14,151 words) - 16:31, 6 December 2024
  • Thumbnail for Ion channel
    allow protons to leave cells. Their function thus appears to be acid extrusion from cells. Another important function occurs in phagocytes (e.g. eosinophils...
    51 KB (5,909 words) - 05:58, 14 December 2024
  • Thumbnail for Cell spreader
    handle. Another variant is a rod bent in L-shape. Extrusion molded versions can be T-shaped. Inoculation loop Ball inoculator Drop cells or bacteria at the...
    4 KB (329 words) - 22:12, 21 November 2023
  • Thumbnail for Boundary representation
    richer operation set. In addition to the Boolean operations, B-rep has extrusion (or sweeping), chamfer, blending, drafting, shelling, tweaking and other...
    9 KB (1,106 words) - 23:52, 14 December 2024
  • cruciform extrusion. DNA in the region of the inverted repeat unwinds and then recombines, forming a four-way junction with two stem-loop structures...
    31 KB (3,451 words) - 20:17, 11 September 2024