• Thumbnail for Lovastatin
    Lovastatin, sold under the brand name Mevacor among others, is a statin medication, to treat high blood cholesterol and reduce the risk of cardiovascular...
    33 KB (3,305 words) - 03:35, 30 September 2024
  • Thumbnail for Red yeast rice
    yeast rice. Chemical analysis soon showed that lovastatin and monacolin K were identical. Lovastatin became the patented prescription drug Mevacor. Red...
    24 KB (2,931 words) - 01:06, 28 September 2024
  • In enzymology, lovastatin nonaketide synthase (EC 2.3.1.161) is an enzyme that catalyzes the chemical reaction acetyl-CoA + 8 malonyl-CoA + 11 NADPH +...
    2 KB (156 words) - 14:47, 26 August 2023
  • of producing 70 mg lovastatin per kilogram of substrate. The red yeast rice fungus, Monascus purpureus, can synthesize lovastatin, mevastatin, and the...
    19 KB (1,718 words) - 19:43, 22 April 2024
  • Thumbnail for Statin
    various forms of statins, some of which include atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, and simvastatin. Combination...
    134 KB (13,062 words) - 13:35, 14 October 2024
  • Thumbnail for Aspergillus terreus
    like xylanase. It was also the initial source for the drug mevinolin (lovastatin), a drug for lowering serum cholesterol. Aspergillus terreus can cause...
    28 KB (3,074 words) - 00:09, 11 January 2024
  • Thumbnail for Niacin/lovastatin
    Niacin/lovastatin (trade names Advicor) was a drug combination used for the treatment of dyslipidemia. It was a combination of the lipid-modifying drug/vitamin...
    3 KB (251 words) - 19:28, 20 December 2023
  • Thumbnail for Pravastatin
    "Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin". Clinical Pharmacokinetics. 47 (7): 463–474...
    14 KB (1,096 words) - 19:44, 21 September 2024
  • Thumbnail for Swanson Health Products
    of SHP's red yeast rice supplements contained significant amounts of lovastatin, the active ingredient in Mevacor and its generic counterparts. The FDA...
    6 KB (601 words) - 08:45, 8 September 2024
  • Atorvastatin Rosuvastatin Lovastatin is derived from a fungus source and simvastatin and pravastatin are chemical modifications of lovastatin and as a result do...
    23 KB (2,423 words) - 18:34, 11 September 2024
  • Thumbnail for Secondary metabolite
    from Tolypocladium inflatum. Lovastatin was the first FDA approved secondary metabolite to lower cholesterol levels. Lovastatin occurs naturally in low concentrations...
    36 KB (3,675 words) - 08:03, 19 October 2024
  • Thumbnail for Fluvastatin
    characteristic side effects for statins, can also occur. Contrary to lovastatin, simvastatin and atorvastatin, fluvastatin has no relevant interactions...
    9 KB (721 words) - 21:03, 4 September 2024
  • high‐risk patients. Atorvastatin, fluvastatin, lovastatin, and pravastatin are alternatives fluvastatin, lovastatin, pravastatin, and simvastatin are alternatives...
    67 KB (4,835 words) - 05:59, 17 August 2024
  • Thumbnail for Simvastatin
    and colleagues isolated lovastatin from a strain of the fungus Aspergillus terreus. While developing and researching lovastatin, Merck scientists synthetically...
    33 KB (3,284 words) - 00:33, 1 September 2024
  • Thumbnail for Mold
    USDA and by Pfizer. Several statin cholesterol-lowering drugs (such as lovastatin, from Aspergillus terreus) are derived from molds. The immunosuppressant...
    31 KB (3,341 words) - 13:27, 3 October 2024
  • Thumbnail for Mexazolam
    HMG-CoA reductase inhibitors including simvastatin, simvastatin acid, lovastatin, fluvastatin, atorvastatin and cerivastatin inhibit the metabolism of...
    5 KB (356 words) - 08:26, 9 September 2024
  • Thumbnail for Hevea brasiliensis
    for linustatin because it is a diglucoside - in fact, the production of lovastatin inhibits linamarase cleavage of linamarin. This allows intra-plant, post-synthesis...
    17 KB (1,820 words) - 17:53, 19 October 2024
  • Thumbnail for HMG-CoA reductase
    these is monacolin K, or lovastatin (previously sold under the trade name Mevacor, and now available as generic lovastatin). Vytorin is drug that combines...
    34 KB (4,113 words) - 16:29, 29 July 2024
  • Thumbnail for Niacin
    combined with lovastatin (Advicor), and with simvastatin (Simcor), as prescription drug combinations. The combination niacin/lovastatin was approved by...
    92 KB (8,792 words) - 14:49, 24 September 2024
  • "Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis". Science. 284 (5418): 1368–1372. Bibcode:1999Sci...284.1368K...
    5 KB (400 words) - 15:12, 17 October 2024
  • group of compounds found in yeast species: Monacolin J Monacolin K or lovastatin Monacolin M [wikidata] This set index article includes a list of related...
    471 bytes (67 words) - 03:00, 28 August 2024
  • Thumbnail for Erythromycin
    — drugs that are broken down by CYP3A — such as simvastatin (Zocor), lovastatin (Mevacor), or atorvastatin (Lipitor) — are taken concomitantly with erythromycin...
    42 KB (3,900 words) - 21:05, 19 October 2024
  • Thumbnail for Cerivastatin
    activity of cerivastatin was compared to that of other statins, specifically lovastatin, simvastatin and pravastatin. This comparison was made by determining...
    16 KB (1,781 words) - 20:57, 4 September 2024
  • Thumbnail for Fungus
    statins found in fungi include mevastatin from Penicillium citrinum and lovastatin from Aspergillus terreus and the oyster mushroom. Psilocybin from fungi...
    200 KB (19,174 words) - 03:56, 29 September 2024
  • Thumbnail for Monascus purpureus
    medical uses. It produces a number of statins. The naturally occurring lovastatins and analogs are called monacolins K, L, J, and also occur in their hydroxyl...
    7 KB (715 words) - 01:13, 2 June 2024
  • Thumbnail for Medication
    chlorpromazine, reserpine, chlordiazepoxide, diazepam, and alprazolam Statins: lovastatin, pravastatin, and simvastatin Pharmaceuticals may also be described as...
    69 KB (7,416 words) - 18:18, 17 October 2024
  • Thumbnail for Clarithromycin
    liver impairment. Concomitant use with cholesterol medications such as lovastatin or simvastatin. Hypersensitivity to clarithromycin or any component of...
    29 KB (2,711 words) - 12:25, 26 September 2024
  • Thumbnail for Butylated hydroxyanisole
    used in medicines, such as cholecalciferol (vitamin D3), isotretinoin, lovastatin, and simvastatin, among others. The U.S. National Institutes of Health...
    8 KB (619 words) - 03:36, 16 January 2024
  • Thumbnail for Fentanyl
    Linolenic acid: α-Linolenic acid and γ-linolenic acid LOE-908 Loratadine Lovastatin Meclizine Metacycline Methylprednisolone Metyrapone Mevastatin Mifepristone...
    174 KB (16,180 words) - 23:05, 20 October 2024
  • Thumbnail for Fenbendazole
    Linolenic acid: α-Linolenic acid and γ-linolenic acid LOE-908 Loratadine Lovastatin Meclizine Metacycline Methylprednisolone Metyrapone Mevastatin Mifepristone...
    9 KB (687 words) - 18:36, 10 October 2024