Methionine synthase (MS, MeSe, MTR) is primarily responsible for the regeneration of methionine from homocysteine in most individuals. In humans it is...
30 KB (3,437 words) - 07:25, 16 May 2024
(3) Adenosylhomocysteinase cysteine. Methionine can be regenerated from homocysteine via (4) methionine synthase in a reaction that requires vitamin B12...
30 KB (3,083 words) - 04:36, 29 March 2025
Methionine synthase reductase, also known as MSR, is an enzyme that in humans is encoded by the MTRR gene. Methionine is an essential amino acid required...
44 KB (5,274 words) - 18:33, 3 May 2024
Homocystinuria (redirect from Cystathionine beta synthase deficiency)
the metabolism of the amino acid methionine due to a deficiency of cystathionine beta synthase or methionine synthase. It is an inherited autosomal recessive...
13 KB (1,363 words) - 21:19, 25 December 2024
Methylation (section Methionine synthase)
N-methylhistidine, and two isomers of N-methylarginine. Methionine synthase regenerates methionine (Met) from homocysteine (Hcy). The overall reaction transforms...
28 KB (3,059 words) - 01:10, 17 February 2025
Vitamin B12 (section Methionine synthase)
neurotoxic dicarboxylic acid, causing neurological deterioration. Methionine synthase, coded by MTR gene, is a methyltransferase enzyme which uses the...
114 KB (12,440 words) - 15:34, 10 April 2025
[Methionine synthase] reductase, or Methionine synthase reductase, encoded by the gene MTRR, is an enzyme that is responsible for the reduction of methionine...
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10-methylenetetrahydrofolate (MTHF) and used to recycle homocysteine back to methionine by methionine synthase (MS). L-Methylfolate is water-soluble and primarily excreted...
15 KB (1,214 words) - 02:20, 10 February 2025
conversion of this intermediate to methionine, through a methylation reaction carried out by methionine synthase. The reverse pathway is present in several...
6 KB (831 words) - 00:32, 17 October 2024
range of macromolecules by the suspected copper-dependent enzyme methionine synthase. This cycle is able to produce purines, which are a component of...
28 KB (2,727 words) - 20:58, 2 January 2025
Methylcobalamin and 5-methyltetrahydrofolate are needed by methionine synthase in the methionine cycle to transfer a methyl group from 5-methyltetrahydrofolate...
30 KB (2,673 words) - 13:58, 10 April 2025
Homocysteine (section Methionine salvage)
(THF) to give L-methionine.[clarification needed] Mammals biosynthesize the amino acid cysteine via homocysteine. Cystathionine β-synthase catalyses the...
24 KB (2,056 words) - 15:35, 26 April 2025
metabolism, and the activation of methionine synthase, which is the rate-limiting step in the synthesis of methionine from homocysteine and 5-methyltetrahydrofolate...
21 KB (2,027 words) - 00:06, 8 February 2025
back to methionine can occur via either of two pathways. The pathway present in virtually all cells involves the enzyme methionine synthase (MS), which...
22 KB (1,812 words) - 20:50, 31 March 2025
recycled back to methionine through transfer of a methyl group from 5-methyltetrahydrofolate, by one of the two classes of methionine synthases (i.e. cobalamin-dependent...
24 KB (2,420 words) - 02:57, 17 March 2025
toxic amino acid) to methionine by the enzyme methionine synthase. (Note that homocysteine can also be converted to methionine by the folate-independent...
37 KB (3,954 words) - 03:55, 28 April 2025
homocysteine [citation needed] is converted back to methionine by remethylation via the methionine synthase major pathway. This requires active folate and...
20 KB (2,117 words) - 03:35, 4 January 2025
using the enzyme methionine S-methyltransferase and the catalyst methionine synthase. Phenylalanine and tyrosine are grouped together because tyrosine...
27 KB (2,693 words) - 06:58, 9 March 2025
acid synthase, aminocyclopropanecarboxylate synthase, ACC synthase, and S-adenosyl-L-methionine methylthioadenosine-lyase. This enzyme participates...
21 KB (2,514 words) - 10:32, 18 November 2024
B12 is a necessary cofactor for methionine synthase, an enzyme involved in the methylation of homocysteine to methionine. DNA methylation is involved in...
117 KB (12,933 words) - 02:48, 18 March 2025
Cystathionine-β-synthase, also known as CBS, is an enzyme (EC 4.2.1.22) that in humans is encoded by the CBS gene. It catalyzes the first step of the transsulfuration...
26 KB (3,182 words) - 21:20, 25 December 2024
studies of FMN and Vitamin B12 Dependent Enzymes: Flavodoxin and Methionine Synthase". After her PhD, she joined Douglas Rees as a postdoctoral fellow...
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therapy methionine synthase: pernicious anemia, caused by Vitamin B12 deficiency, is caused by a lack of cofactor for the methionine synthase enzyme Recent...
26 KB (2,919 words) - 01:51, 24 December 2024
Phenytoin Nitrous Oxide Erythroleukemia Inborn genetic mutations of the Methionine synthase gene Di Guglielmo's syndrome Congenital dyserythropoietic anemia...
13 KB (1,263 words) - 10:10, 17 March 2025
essential part of the methionine biosynthesis pathway as homocysteine can be directly converted into methionine by methionine synthase. The enzyme belongs...
19 KB (1,960 words) - 12:39, 3 December 2023
5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), also known as methionine synthase.[citation needed] Methylcobalamin participates in the Wood-Ljungdahl...
13 KB (1,114 words) - 14:03, 10 April 2025
tetrahydrofolate and methionine. This reaction is catalyzed by the enzyme methionine synthase with B12 as an essential cofactor. During B12 deficiency, this reaction...
54 KB (6,015 words) - 06:24, 14 April 2025
Idaho, US Mill test report (metals industry) Methionine synthase, responsible for the regeneration of methionine from homocysteine MTR (software), or My traceroute...
2 KB (256 words) - 05:55, 29 September 2024
containing the cobalamin-binding domain include: Animal and prokaryotic methionine synthase (EC 2.1.1.13), which catalyse the transfer of a methyl group from...
7 KB (770 words) - 17:55, 11 March 2024
B12 functions as a co-enzyme in intermediary metabolism for the methionine synthase reaction with methylcobalamin, and the methylmalonyl CoA mutase reaction...
42 KB (2,795 words) - 17:19, 30 March 2025