• Thumbnail for MyoD
    family members include MyoD1, Myf5, myogenin, and MRF4 (Myf6). In non-vertebrate animals, a single MyoD protein is typically found. MyoD is one of the earliest...
    27 KB (3,374 words) - 10:55, 15 July 2024
  • Thumbnail for Myogenesis
    has shown that MyoD directly activates its own gene; this means that the protein made binds the myoD gene and continues a cycle of MyoD protein production...
    24 KB (2,738 words) - 04:06, 17 June 2024
  • E-box (section MYOD1 (MyoD))
    cancer. MyoD can also bind to noncanonical E boxes of MyoG and regulate its expression. MyoG belongs to the MyoD transcription factor family. MyoG-E-Box...
    30 KB (3,663 words) - 06:09, 22 November 2023
  • Thumbnail for MYF5
    forms normally. As no muscle is formed in Myf5;Myod double mutant zebrafish, Myf5 cooperates with Myod to promote myogenesis. The regulation of Myf5 is...
    18 KB (2,355 words) - 11:57, 21 June 2022
  • Thumbnail for Ubiquitin
    being used for ubiquitylation, rather than a lysine residue, in the protein MyoD and has been observed since in 22 other proteins in multiple species, including...
    98 KB (11,068 words) - 18:53, 17 August 2024
  • helix-loop-helix (bHLH) transcription factors that regulate myogenesis: MyoD, Myf5, myogenin, and MRF4. These proteins contain a conserved basic DNA binding...
    3 KB (403 words) - 08:40, 25 July 2024
  • Thumbnail for Myogenin
    myogenesis and repair. Myogenin is a member of the MyoD family of transcription factors, which also includes MyoD, Myf5, and MRF4. In mice, myogenin is essential...
    12 KB (1,497 words) - 08:24, 26 March 2024
  • Thumbnail for Retinoblastoma protein
    deacetylase 2 Insulin JARID1A Large tumor antigen LIN9 MCM7 MORF4L1 MRFAP1, MyoD NCOA6 PA2G4 Peroxisome proliferator-activated receptor gamma PIK3R3 Plasminogen...
    79 KB (9,500 words) - 18:16, 10 June 2024
  • Thumbnail for Transcription factor
    but, once expressed, require no additional activation – GATA, HNF, PIT-1, MyoD, Myf5, Hox, Winged Helix II.B signal-dependent – requires external signal...
    75 KB (8,057 words) - 04:44, 25 July 2024
  • Thumbnail for Inositol
    Inositol (redirect from Myo-inositol)
    biochemistry, medicine, and related sciences, inositol generally refers to myo-inositol (formerly meso-inositol), the most important stereoisomer of the...
    39 KB (4,027 words) - 19:46, 18 August 2024
  • Thumbnail for Induced pluripotent stem cell
    work of Harold Weintraub on the role of myoblast determination protein 1 (MyoD) in reprogramming cell fate to a muscle lineage as an important precursor...
    92 KB (10,498 words) - 20:42, 17 August 2024
  • Thumbnail for NF-κB
    Conti F, Buanne P, Canu N, Caruso M, et al. (March 2005). "PC4 coactivates MyoD by relieving the histone deacetylase 4-mediated inhibition of myocyte enhancer...
    89 KB (9,773 words) - 14:28, 22 August 2024
  • Thumbnail for Myod family inhibitor domain containing
    MyoD family inhibitor domain containing is a protein that in humans is encoded by the MDFIC gene. This gene product is a member of a family of proteins...
    1 KB (195 words) - 19:47, 3 March 2023
  • characterization of "myoD", the first master regulatory gene. When expressed, the myoD gene produces a protein referred to as MyoD (or MyoD1), which can bind...
    19 KB (2,137 words) - 14:13, 14 July 2023
  • Thumbnail for Vitamin D receptor
    The vitamin D receptor (VDR also known as the calcitriol receptor) is a member of the nuclear receptor family of transcription factors. Calcitriol (the...
    22 KB (2,646 words) - 05:40, 13 July 2024
  • Thumbnail for EP300
    HNF1A, HNRPU, ING4, ING5, IRF2, LEF1, MAF, MAML1, MEF2C, MEF2D, MYBL2, Mdm2, MyoD, MEF2A, NCOA6, NFATC2, NPAS2, P53, PAX6, PCNA, PROX1, PTMA, PPARA, PPARG...
    37 KB (4,263 words) - 08:33, 20 June 2024
  • Thumbnail for Chronaxie
    (2007). "Electrical stimulation based on chronaxie reduces atrogin-1 and myod gene expression in denervated rat muscle". Muscle Nerve. 35 (1): 87–97. doi:10...
    17 KB (2,377 words) - 19:43, 28 April 2024
  • Thumbnail for MYF6
    although in mice it is able to initiate myogenesis in the absence of Myf5 and MyoD, two other MRFs. The portion of the protein integral to myogenesis regulation...
    9 KB (1,166 words) - 18:37, 22 August 2024
  • Thumbnail for Ardem Patapoutian
    2021. Patapoutian, Ardem (1996). The Role of the MyoD Family Genes During Mouse Development (Ph.D. thesis). California Institute of Technology. OCLC 35966904...
    33 KB (2,511 words) - 13:34, 11 July 2024
  • Thumbnail for PITX2
    expression of MyoD. However, in the absence of the parallel pathway, Pitx2 can continue activating MyoD genes. The expression of Pitx2 saves MyoD gene expression...
    27 KB (3,419 words) - 08:01, 21 July 2024
  • increased expression of myogenic basic helix-loop-helix transcription factors MyoD, myogenin, and MRF4 – all responsible for the induction of myocyte-specific...
    28 KB (3,408 words) - 17:26, 22 February 2024
  • Thumbnail for IFRD1
    morphological and biochemical differentiation by inhibiting the expression of MyoD and myogenin, key master genes of muscle development. A role for IFRD1 in...
    13 KB (1,603 words) - 23:51, 3 March 2023
  • Thumbnail for Cyclin-dependent kinase 4
    interact with: CDC37, CDKN1B, CDKN2B, CDKN2C, CEBPA, CCND1, CCND3, DBNL, MyoD, P16, PCNA, and SERTAD1. GRCh38: Ensembl release 89: ENSG00000135446 – Ensembl...
    21 KB (2,372 words) - 12:19, 28 July 2024
  • Thumbnail for Muscle cell
    Differentiation is regulated by myogenic regulatory factors, including MyoD, Myf5, myogenin, and MRF4. GATA4 and GATA6 also play a role in myocyte differentiation...
    37 KB (4,500 words) - 22:16, 12 July 2024
  • and GSK3 interaction. During myogenesis, Wnt uses PA and CREB to activate MyoD and Myf5 genes. Wnt also acts in conjunction with Ryk and Src to allow for...
    64 KB (7,427 words) - 21:08, 3 August 2024
  • Thumbnail for Sex-determining region Y protein
    Sertoli cells, SOX9 directly targets the Amh gene as well as the prostaglandin D synthase (Ptgds) gene. SOX9 binding to the enhancer near the Amh promoter...
    39 KB (4,859 words) - 19:32, 22 August 2024
  • Thumbnail for MDFI
    MyoD family inhibitor is a protein that in humans is encoded by the MDFI gene. This protein is a transcription factor that negatively regulates other myogenic...
    6 KB (744 words) - 23:26, 3 March 2023
  • adult cell type to another. Forcing mouse embryonic fibroblasts to express MyoD was found to be sufficient to turn those cells into myoblasts. The only[citation...
    31 KB (3,333 words) - 18:59, 17 August 2023
  • Thumbnail for Histone acetyltransferase
    proteins HMG-N2/HMG17 and HMG-I(Y), the transcriptional activators p53, MyoD, E2F(1-3), and HIV Tat, and the general transcription factors TFIIE and TFIIF...
    53 KB (6,148 words) - 01:29, 28 July 2024
  • Thumbnail for BHLHE41
    (H3K9me2) at promoter sites of target genes of MyoD. G9a also methylates MyoD, which inhibits MyoD's transcriptional activity. BHLHE41 and BHLHE40 are...
    27 KB (3,158 words) - 20:58, 17 August 2024