family members include MyoD1, Myf5, myogenin, and MRF4 (Myf6). In non-vertebrate animals, a single MyoD protein is typically found. MyoD is one of the earliest...
27 KB (3,374 words) - 10:55, 15 July 2024
has shown that MyoD directly activates its own gene; this means that the protein made binds the myoD gene and continues a cycle of MyoD protein production...
24 KB (2,738 words) - 04:06, 17 June 2024
E-box (section MYOD1 (MyoD))
cancer. MyoD can also bind to noncanonical E boxes of MyoG and regulate its expression. MyoG belongs to the MyoD transcription factor family. MyoG-E-Box...
30 KB (3,663 words) - 06:09, 22 November 2023
forms normally. As no muscle is formed in Myf5;Myod double mutant zebrafish, Myf5 cooperates with Myod to promote myogenesis. The regulation of Myf5 is...
18 KB (2,355 words) - 11:57, 21 June 2022
being used for ubiquitylation, rather than a lysine residue, in the protein MyoD and has been observed since in 22 other proteins in multiple species, including...
98 KB (11,068 words) - 18:53, 17 August 2024
helix-loop-helix (bHLH) transcription factors that regulate myogenesis: MyoD, Myf5, myogenin, and MRF4. These proteins contain a conserved basic DNA binding...
3 KB (403 words) - 08:40, 25 July 2024
myogenesis and repair. Myogenin is a member of the MyoD family of transcription factors, which also includes MyoD, Myf5, and MRF4. In mice, myogenin is essential...
12 KB (1,497 words) - 08:24, 26 March 2024
deacetylase 2 Insulin JARID1A Large tumor antigen LIN9 MCM7 MORF4L1 MRFAP1, MyoD NCOA6 PA2G4 Peroxisome proliferator-activated receptor gamma PIK3R3 Plasminogen...
79 KB (9,500 words) - 18:16, 10 June 2024
but, once expressed, require no additional activation – GATA, HNF, PIT-1, MyoD, Myf5, Hox, Winged Helix II.B signal-dependent – requires external signal...
75 KB (8,057 words) - 04:44, 25 July 2024
Inositol (redirect from Myo-inositol)
biochemistry, medicine, and related sciences, inositol generally refers to myo-inositol (formerly meso-inositol), the most important stereoisomer of the...
39 KB (4,027 words) - 19:46, 18 August 2024
work of Harold Weintraub on the role of myoblast determination protein 1 (MyoD) in reprogramming cell fate to a muscle lineage as an important precursor...
92 KB (10,498 words) - 20:42, 17 August 2024
Conti F, Buanne P, Canu N, Caruso M, et al. (March 2005). "PC4 coactivates MyoD by relieving the histone deacetylase 4-mediated inhibition of myocyte enhancer...
89 KB (9,773 words) - 14:28, 22 August 2024
MyoD family inhibitor domain containing is a protein that in humans is encoded by the MDFIC gene. This gene product is a member of a family of proteins...
1 KB (195 words) - 19:47, 3 March 2023
characterization of "myoD", the first master regulatory gene. When expressed, the myoD gene produces a protein referred to as MyoD (or MyoD1), which can bind...
19 KB (2,137 words) - 14:13, 14 July 2023
The vitamin D receptor (VDR also known as the calcitriol receptor) is a member of the nuclear receptor family of transcription factors. Calcitriol (the...
22 KB (2,646 words) - 05:40, 13 July 2024
HNF1A, HNRPU, ING4, ING5, IRF2, LEF1, MAF, MAML1, MEF2C, MEF2D, MYBL2, Mdm2, MyoD, MEF2A, NCOA6, NFATC2, NPAS2, P53, PAX6, PCNA, PROX1, PTMA, PPARA, PPARG...
37 KB (4,263 words) - 08:33, 20 June 2024
(2007). "Electrical stimulation based on chronaxie reduces atrogin-1 and myod gene expression in denervated rat muscle". Muscle Nerve. 35 (1): 87–97. doi:10...
17 KB (2,377 words) - 19:43, 28 April 2024
although in mice it is able to initiate myogenesis in the absence of Myf5 and MyoD, two other MRFs. The portion of the protein integral to myogenesis regulation...
9 KB (1,166 words) - 18:37, 22 August 2024
2021. Patapoutian, Ardem (1996). The Role of the MyoD Family Genes During Mouse Development (Ph.D. thesis). California Institute of Technology. OCLC 35966904...
33 KB (2,511 words) - 13:34, 11 July 2024
expression of MyoD. However, in the absence of the parallel pathway, Pitx2 can continue activating MyoD genes. The expression of Pitx2 saves MyoD gene expression...
27 KB (3,419 words) - 08:01, 21 July 2024
increased expression of myogenic basic helix-loop-helix transcription factors MyoD, myogenin, and MRF4 – all responsible for the induction of myocyte-specific...
28 KB (3,408 words) - 17:26, 22 February 2024
morphological and biochemical differentiation by inhibiting the expression of MyoD and myogenin, key master genes of muscle development. A role for IFRD1 in...
13 KB (1,603 words) - 23:51, 3 March 2023
interact with: CDC37, CDKN1B, CDKN2B, CDKN2C, CEBPA, CCND1, CCND3, DBNL, MyoD, P16, PCNA, and SERTAD1. GRCh38: Ensembl release 89: ENSG00000135446 – Ensembl...
21 KB (2,372 words) - 12:19, 28 July 2024
Differentiation is regulated by myogenic regulatory factors, including MyoD, Myf5, myogenin, and MRF4. GATA4 and GATA6 also play a role in myocyte differentiation...
37 KB (4,500 words) - 22:16, 12 July 2024
and GSK3 interaction. During myogenesis, Wnt uses PA and CREB to activate MyoD and Myf5 genes. Wnt also acts in conjunction with Ryk and Src to allow for...
64 KB (7,427 words) - 21:08, 3 August 2024
Sertoli cells, SOX9 directly targets the Amh gene as well as the prostaglandin D synthase (Ptgds) gene. SOX9 binding to the enhancer near the Amh promoter...
39 KB (4,859 words) - 19:32, 22 August 2024
MyoD family inhibitor is a protein that in humans is encoded by the MDFI gene. This protein is a transcription factor that negatively regulates other myogenic...
6 KB (744 words) - 23:26, 3 March 2023
adult cell type to another. Forcing mouse embryonic fibroblasts to express MyoD was found to be sufficient to turn those cells into myoblasts. The only[citation...
31 KB (3,333 words) - 18:59, 17 August 2023
proteins HMG-N2/HMG17 and HMG-I(Y), the transcriptional activators p53, MyoD, E2F(1-3), and HIV Tat, and the general transcription factors TFIIE and TFIIF...
53 KB (6,148 words) - 01:29, 28 July 2024
(H3K9me2) at promoter sites of target genes of MyoD. G9a also methylates MyoD, which inhibits MyoD's transcriptional activity. BHLHE41 and BHLHE40 are...
27 KB (3,158 words) - 20:58, 17 August 2024