Nectins and Nectin-like molecules (Necl) are families of cellular adhesion molecules involved in Ca2+-independent cellular adhesion. Nectins are ubiquitously...

Nectin-3, also known as nectin cell adhesion molecule 3, is a protein that in humans is encoded by the NECTIN3 gene. Nectin-3 belongs to the family of...

Poliovirus receptor-related 1 (PVRL1), also known as nectin-1 and CD111 (formerly herpesvirus entry mediator C, HVEC) is a human protein of the immunoglobulin...

Poliovirus receptor-related 2 (PVRL2), also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), is a human plasma membrane glycoprotein...

cell adhesion molecule Nectin-4. For wild type and vaccine strains, extracellular domains of CD150 (SLAM or SLAMF1) and/or of nectin-4 (also called...

antibody-drug conjugate used for the treatment of urothelial cancer. It is a nectin-4-directed antibody and microtubule inhibitor conjugate. Enfortumab refers...

mediates cellular adhesion to other cells bearing its ligands, nectin molecule CD112 and nectin-like protein CD155, that are broadly distributed on normal...

receptors include herpesvirus entry mediator (HVEM), nectin-1 and 3-O sulfated heparan sulfate. The nectin receptors usually produce cell-cell adhesion, to...

found on immune cells like B or T cells, and antigen-presenting cells, or nectin-4, a cellular adhesion molecule. Once bound, the fusion, or F protein helps...

leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112)". Blood. 105 (5): 2066–73. doi:10.1182/blood-2004-09-3548. PMID 15536144...

ASG-22M6E): product candidate for the treatment of solid tumours (targets Nectin-4 in bladder, breast, lung and pancreatic cancer); developed in 50-50 partnership...

filaments Integrins EC matrix Adherens junctions (Adhesion belt, Focal adhesion) Actin filaments Cadherin / Integrin / Nectins Other cells / EC matrix...

PMC 7086627. PMID 19495937. Mueller S, Wimmer E (August 2003). "Recruitment of nectin-3 to cell-cell junctions through trans-heterophilic interaction with CD155...

of cases. Virus enters into susceptible cells by entry receptors such as nectin-1, HVEM and 3-O sulfated heparan sulfate. Infected people who show no visible...

ensure stability of synaptic components SynCAM’s (also known as Cadm or nectin-like molecules) are a specific type of synaptic CAM found in vertebrates...

including ovarian and pancreatic cancer. The conjugate consists of a human anti-nectin-4 antibody linked to the cytotoxic agent MMAE, which is released after internalization...

PMC 4222184. PMID 25080364. Noyce RS, Richardson CD (September 2012). "Nectin 4 is the epithelial cell receptor for measles virus". Trends in Microbiology...

in aid of viral entry" (2001) "Striking similarity of murine nectin-1alpha to human nectin-1alpha (HveC) in sequence and activity as a glycoprotein D receptor...

humanized TWEAK receptor cancer etc. Enfortumab vedotin Padcev mab human nectin-4 Y urothelial cancer Enlimomab pegol mab mouse ICAM-1 (CD54) Enoblituzumab...

Satoh A, Nishioka H, Aoki J, Nomoto A, Mizoguchi A, Takai Y (May 1999). "Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based...

It is caused by mutations in the gene PVRL1 (11q23-q24) which encodes nectin-1, the principal receptor used by alpha-herpesviruses to mediate entry into...

A, Colonna M (October 2006). "The role of NK cell recognition of nectin and nectin-like proteins in tumor immunosurveillance". Seminars in Cancer Biology...

associated with forms of anemia, myelofibrosis and thrombocythemia. CD111 Nectin-1 or Herpesvirus entry mediator C (HveC), encoded by the PVRL1 (Poliovirus...

family CTX Junctional adhesion molecule BT-IGSF CAR VSIG ESAM Nectins PVRL1 PVRL2 PVRL3 Nectin-4 CADM1 CADM3 NECL3 NECL4 NECL5 CD2 family CD2 CD58 Signaling...

cell to attach to it and are then endocytosed. For example, HSV uses the nectin receptor and is then endocytosed. After endocytosis, the low pH inside the...

related to the calcium-independent cell-cell adhesion molecules known as nectins (see PVRL3; MIM 607147) (Kakunaga et al., 2005). GRCh38: Ensembl release...

tibtech.2009.02.002. Epub 2009 Mar 25. Review. Adherens junction protein nectin-4 is the epithelial receptor for measles virus. Mühlebach MD, Mateo M, Sinn...

and fibronectin, which are natural ECM components, and ProNectin F plus (Pro-F) and ProNectin L (Pro-L), which are artificial ECM components, and poly(ethyleneimine)...

"Search for polymorphisms in the genes for herpesvirus entry mediator, nectin-1, and nectin-2 in immune seronegative individuals". The Journal of Infectious...

PMID 2538245. S2CID 44296539. Mueller, S.; Wimmer, E. (2003). "Recruitment of Nectin-3 to cell-cell junctions through trans-heterophilic interaction with CD155...