Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival...
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neurotrophic factor (BDNF) Nerve growth factor (NGF) Neurotrophin-3 (NT-3) Neurotrophin-4 (NT-4) Placental growth factor (PGF) Platelet-derived growth factor (PDGF)...
10 KB (1,131 words) - 19:14, 31 March 2024
low-affinity nerve growth factor receptor (LNGFR) before discovery that p75NTR bound other neurotrophins equally well as nerve growth factor. p75NTR is...
37 KB (4,235 words) - 13:48, 29 June 2024
Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
17 KB (1,708 words) - 22:30, 15 October 2024
Nerve growth factor (NGF) inhibitors are a class of compounds that inhibit the action of the neurotrophin nerve growth factor by targeting NGF molecules...
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Neurotrophin (redirect from Neuronal growth associated protein)
for neurotrophic factor, but the term neurotrophin is more generally reserved for four structurally related factors: nerve growth factor (NGF), brain-derived...
27 KB (3,082 words) - 16:34, 16 October 2024
growth factors, which are related to the canonical nerve growth factor (NGF), a family which also includes NT-3 and NT-4/NT-5. Neurotrophic factors are found...
46 KB (5,344 words) - 17:28, 12 October 2024
Cenegermin (redirect from Recombinant human nerve growth factor)
Oxervate, also known as recombinant human nerve growth factor (rhNGF), is a recombinant form of human nerve growth factor (NGF). In July 2017, it was approved...
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neurotrophic factors are being intensely studied for use in bioartificial nerve conduits because they are necessary in vivo for directing axon growth and regeneration...
16 KB (1,784 words) - 04:08, 6 January 2024
Neurotrophic factor receptors or neurotrophin receptors are a group of growth factor receptors which specifically bind to neurotrophins (neurotrophic factors). Two...
5 KB (670 words) - 17:28, 23 January 2021
PC12 cell line (section Nerve Growth Factor)
cells stop dividing and terminally differentiate when treated with nerve growth factor or dexamethasone. This makes PC12 cells useful as a model system...
10 KB (1,002 words) - 02:01, 3 December 2023
monoclonal antibody against nerve growth factor[31] Fulranumab (AMG-403, JNJ-42160443) – monoclonal antibody against nerve growth factor [32] GBR-900 – monoclonal...
18 KB (1,274 words) - 09:53, 9 January 2024
neurotrophic factors such as nerve growth factor (NGF) and ciliary neurotrophic factor (CNTF), which promote growth, of both the damaged nerve and supporting...
34 KB (4,113 words) - 01:03, 12 July 2024
Fibroblast growth factors (FGF) are a family of cell signalling proteins produced by macrophages; they are involved in a wide variety of processes, most...
25 KB (3,124 words) - 21:38, 18 August 2024
Nuclear receptor 4A1 (redirect from Nerve growth factor ib)
1621/nrs.04002. PMC 1402209. PMID 16604165. Milbrandt J (May 1988). "Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene". Neuron...
21 KB (2,530 words) - 02:53, 28 March 2024
Medicine jointly with colleague Stanley Cohen for the discovery of nerve growth factor (NGF). From 2001 until her death, she also served in the Italian...
50 KB (5,000 words) - 09:05, 13 September 2024
Nociceptor (redirect from Pain nerve)
such as ATP, which can be detected by P2 purinergic receptors, or nerve growth factor, which can be detected by Tropomyosin receptor kinase A (TrkA). Chemical...
23 KB (2,811 words) - 09:50, 13 September 2024
Tropomyosin receptor kinase A (TrkA), also known as high affinity nerve growth factor receptor, neurotrophic tyrosine kinase receptor type 1, or TRK1-transforming...
27 KB (3,264 words) - 05:43, 13 April 2024
Neurotrophin-3 (redirect from Neurotrophic Factor-3)
gene, NT-3, is a neurotrophic factor in the NGF (Nerve Growth Factor) family of neurotrophins. It is a protein growth factor which has activity on certain...
14 KB (1,816 words) - 04:39, 31 October 2023
2021). "Laboratory safety evaluation of bedinvetmab, a canine anti-nerve growth factor monoclonal antibody, in dogs". Veterinary Journal. 276: 105733. doi:10...
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Physiology or Medicine in 1986 for the isolation of nerve growth factor and the discovery of epidermal growth factor. He died in February 2020 at the age of 97...
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Hertha Meyer (section Discovery of nerve growth factor)
cell organelles. Her cell culture method led to the discovery of nerve growth factor, a protein that regulates development and survival of neurones. Meyer...
27 KB (3,000 words) - 19:50, 9 March 2024
TrkA and TrkC. There are other neurotrophic factors structurally related to BDNF: NGF (for nerve growth factor), NT-3 (for neurotrophin-3) and NT-4 (for...
40 KB (4,319 words) - 02:54, 11 August 2024
the neurotrophic tyrosine kinase receptor. NTRK1 is a receptor for nerve growth factor (NGF). This protein induces outgrowth of axons and dendrites and...
8 KB (737 words) - 13:55, 15 October 2024
fruiting body of Hericium erinaceum (lion's mane mushroom) that promote nerve growth factor synthesis in vitro. Kawagishi, Hirokazu; Ando, Motoharu; Shinba,...
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Anabasis product cenegermin, an eye drop containing recombinant human nerve growth factor, as a treatment for neurotrophic keratitis. Cenegermin was approved...
2 KB (202 words) - 09:25, 19 June 2024
neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), and ciliary neurotrophic factor (CNTF). Although...
13 KB (1,177 words) - 02:19, 4 September 2024
fiber degeneration of affected neurons and their projecting axons. Nerve growth factor protects cholinergic neurons. The small non-toxic molecule urea has...
20 KB (2,446 words) - 00:41, 16 December 2023
analgesic effects of alpha-2 adrenergic receptor agonists bedinvetmab - nerve growth factor inhibitor monoclonal antibody used for osteoarthritis in dogs benazepril...
11 KB (1,144 words) - 12:20, 8 August 2024
transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix metalloproteinase, beta subunit of pro-nerve growth factor and...
17 KB (2,288 words) - 15:22, 19 March 2024