• In organic chemistry, the Mannich reaction is a three-component organic reaction that involves the amino alkylation of an acidic proton next to a carbonyl...
    10 KB (1,017 words) - 16:55, 26 September 2024
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    The nitro-Mannich reaction (or aza-Henry reaction) is the nucleophilic addition of a nitroalkane (or the corresponding nitronate anion) to an imine, resulting...
    25 KB (2,892 words) - 22:19, 27 September 2024
  • method using sulfuric acid. The Michael reaction can occur under neutral conditions through an enamine. A Mannich base can be heated in the presence of...
    15 KB (1,746 words) - 15:21, 26 September 2024
  • olefination Kabachnik–Fields reaction Kharasch–Sosnovsky reaction Keck asymmetric allylation Ketimine Mannich reaction Ketone halogenation Kiliani–Fischer...
    37 KB (3,419 words) - 11:08, 19 October 2024
  • development of related reactions including the Michael addition, asymmetric aldol reaction, and the Mannich reaction. This reaction has likewise been used...
    20 KB (1,841 words) - 15:30, 19 May 2024
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    A00270 Gaudry, Michel; Jasor, Yves; Khac, Trung Bui (1979). "Regioselective Mannich Condensation with Dimethyl(Methylene)ammonium Trifluoroacetate:...
    2 KB (284 words) - 19:10, 19 October 2023
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    reduction of its oxime. Henry reaction of piperonal with nitroethane followed by nitro compound reduction. Darzens reaction on heliotropin was also done...
    24 KB (2,233 words) - 07:24, 24 October 2024
  • Thumbnail for Thioester
    Thioester (section Reactions)
    acetate salt is rarely practiced. The alkylation can be conducted using Mannich bases and the thiocarboxylic acid: CH3COSH + R'2NCH2OH → CH3COSCH2NR'2...
    13 KB (1,388 words) - 20:22, 15 September 2024
  • CuFe2O4 catalyst was demonstrated its activity for C-H activation in Mannich type reaction. In the mechanistic study, the copper play a significant role in...
    25 KB (2,299 words) - 00:28, 18 October 2024
  • Thumbnail for Hydrogen-bond catalysis
    such as aldol additions, Diels-Alder cycloadditions and Mannich reactions. Many organic reactions involve the formation of tetrahedral intermediates through...
    32 KB (3,990 words) - 10:15, 26 September 2024
  • Thumbnail for Benjamin List
    Hajos–Parrish–Eder–Sauer–Wiechert reaction. Subsequently, he developed the first proline-catalyzed Mannich, Michael, and α-amination reactions. He found asymmetric...
    24 KB (2,117 words) - 10:06, 3 November 2024
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    substitution but will also become part of the strychnine skeleton. A Mannich reaction with formaldehyde and dimethylamine) produced gramine 4. Alkylation...
    39 KB (4,087 words) - 03:50, 29 February 2024
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    S-Methyl-N-nitro-isothiourea is treated with methylamine to give N-methyl nitroguanidine. This intermediate is used in a Mannich reaction with formaldehyde...
    21 KB (1,974 words) - 00:20, 23 October 2024