Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that exists in all eukaryotes. Its main function is to reduce errors in gene expression by...
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Messenger RNA (section Nonsense-mediated decay)
subject to surveillance by nonsense-mediated decay (NMD), which checks for the presence of premature stop codons (nonsense codons) in the message. These...
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MRNA surveillance (redirect from No-Go decay)
nonsense-mediated mRNA decay pathway (NMD); the nonstop mediated mRNA decay pathways (NSD); and the no-go mediated mRNA decay pathway (NGD). Nonsense-mediated...
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recognition in translation, termination of translation, and nonsense mediated mRNA decay via the SURF complex. All cells need to make proteins through...
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splicing, but along with Y14, it also takes part in the process of nonsense-mediated decay in eukaryotes. SRm160 is another coactivator that has been proposed...
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SR protein (section Nonsense-mediated decay)
alternative pre-mRNA splicing, mRNA export, genome stabilization, nonsense-mediated decay, and translation. SR proteins alternatively splice pre-mRNA by...
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ways that it does this quality control is through nonsense-mediated decay. Nonsense-mediated decay is when faulty mRNA's that have stop codons too early...
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between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa...
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between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa...
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types of situations with nonsense mutations occur a lot less frequently than the deleterious outcomes. Nonsense-mediated mRNA decay Despite an expected tendency...
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between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa...
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In contrast to nonsense-mediated decay (NMD), polypeptides do not release from the ribosome, and thus, NSD seems to involve mRNA decay factors distinct...
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between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa...
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Messenger RNA decapping (section Translation and decay)
A number of specific decay pathways exist that recognize aberrant messages and promote their decapping. Nonsense mediated decay recognizes premature stop...
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Synthetic rescue (section Dosage-mediated suppression)
partially completed polypeptide or degradation of the mRNA by nonsense-mediated decay. The redundancy of tRNA genes makes sure that such mutation would...
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errors explains why most splice variants are rapidly degraded by nonsense-mediated decay. The presence of sloppy binding sites within genes causes splicing...
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encode different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). Alpha-synuclein (α-Syn) aggregation via Lewy bodies inclusion...
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Deaths, a humanitarian aid organization Non-metropolitan district Nonsense mediated decay, a mechanism of messenger RNA surveillance Norsk Medisinaldepot...
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nonsense mediated mRNA decay factor (C. elegans)". Yang L, Kraft VA, Pfeiffer S, Merl-Pham J, Bao X, An Y, et al. (June 2020). "Nonsense-mediated decay...
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pseudogene because all associated transcripts are candidates for nonsense-mediated decay (NMD). Rahim MM, Tu MM, Mahmoud AB, Wight A, Abou-Samra E, Lima...
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eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay". Nature. 427 (6976): 753–7. Bibcode:2004Natur.427..753P. doi:10...
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of a human decapping complex associated with hUpf proteins in nonsense-mediated decay". Molecular and Cellular Biology. 22 (23): 8114–8121. doi:10.1128/MCB...
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high translational activity. PABPC1 is also associated with nonsense-mediated mRNA decay (NMD). PABPC1 binds to the poly(A) tail and interact with eIF4G...
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encode different isoforms have been identified although some fit nonsense-mediated decay criteria. The receptor is found in the central and peripheral nervous...
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decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature...
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Cytoplasmic Isoforms Differentially Regulate Alternative Splicing and Nonsense-Mediated Decay of Rbfox2". PLOS ONE. 6 (6): e21585. Bibcode:2011PLoSO...621585D...
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carrying the frameshift mutation may also be degraded through Nonsense-mediated decay during translation, thus not resulting in any protein product....
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length by increasing euchromatin formation. On the other hand, nonsense-mediated decay factor enrichment at telomeres may exist to prevent TERRA inhibition...
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upstream ORFs and transcripts that are predicted to be candidates for nonsense-mediated decay. Curation occurs continuously, and any of the collaborating centers...
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single-stranded DNA in telomere maintenance and single-stranded RNA in nonsense-mediated mRNA decay (NMD). The SMG6 gene also contains one of 27 SNPs associated...
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