called P450-containing monooxygenase systems, although self-sufficient, non-monooxygenase P450s have been also described. All known P450-containing monooxygenase...

enzymes in electron transfer chains, broadly categorized as P450-containing systems. The term "P450" is derived from the spectrophotometric peak at the wavelength...

ISBN 0-8493-2983-3. Databases Drug metabolism database Directory of P450-containing Systems University of Minnesota Biocatalysis/Biodegradation Database SPORCalc...

In biochemistry, cytochrome P450 enzymes have been identified in all kingdoms of life: animals, plants, fungi, protists, bacteria, and archaea, as well...

ISBN 0-8493-2983-3. Databases Drug metabolism database Directory of P450-containing Systems University of Minnesota Biocatalysis/Biodegradation Database Drug...

Cytochrome P450 reductase (also known as NADPH:ferrihemoprotein oxidoreductase, NADPH:hemoprotein oxidoreductase, NADPH:P450 oxidoreductase, P450 reductase...

Cytochrome P450 1A2 (abbreviated CYP1A2), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in...

Cytochrome P450 3A4 (abbreviated CYP3A4) (EC 1.14.13.97) is an important enzyme in the body, mainly found in the liver and in the intestine, which in humans...

Cytochrome P450 family 2 subfamily C member 9 (abbreviated CYP2C9) is an enzyme protein. The enzyme is involved in the metabolism, by oxidation, of both...

This article covers protein engineering of cytochrome (CYP) P450 enzymes. P450s are involved in a range of biochemical catabolic and anabolic process....

NADPH-cytochrome P450 reductase in the baculovirus/insect cell system". Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 31 (6): 345–56...

ferricytochrome b5 + H2O Cytochrome b Cytochrome b5 deficiency P450-containing systems Cytochrome b5, type A Lederer F (1994). "The cytochrome b5-fold:...

Cytochrome P450 2E1 (abbreviated CYP2E1, EC 1.14.13.n7) is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism...

heme of the P450. The P450 systems that are located in the mitochondria are dependent on two electron transfer proteins: An FAD containing adrenodoxin...

cytochrome P450 enzyme that is involved in the conversion of lanosterol to 4,4-dimethylcholesta-8(9),14,24-trien-3β-ol. The cytochrome P450 isoenzymes...

Cytochrome P450 aromatic O-demethylase is a bacterial enzyme that catalyzes the demethylation of lignin and various lignols. The net reaction follows the...

phase 1 metabolism of amphetamine analogs is catalyzed by two systems: cytochrome P450 and flavin monooxygenase. ... Amphetamine can also undergo aromatic...

responsible for its hepatotoxicity, is formed from it by the cytochrome P450 system (specifically, CYP1A2, CYP2E1, and CYP3A4). Used in cancer metastasis...

phase 1 metabolism of amphetamine analogs is catalyzed by two systems: cytochrome P450 and flavin monooxygenase. Cashman JR, Xiong YN, Xu L, Janowsky...

cancer, including melanoma. Vitamin D requires activation by cytochrome P450 (CYP) enzymes to become active and bind to the VDR. Specifically, CYP27A1...

CoQ10 may interfere with warfarin's actions by interacting with cytochrome p450 enzymes thereby reducing the INR, a measure of blood clotting. The structure...

interactions than erythromycin as it has a lower affinity for cytochrome P450. Roxithromycin is not known to interact with hormonal contraceptives, prednisolone...

misclassified because they share activity profiles similar to those of cytochrome P450 (CYP450), which is the major contributor to oxidative xenobiotic metabolism...

vitro studies show that quercetin is a strong inhibitor of the cytochrome P450 enzymes CYP3A4 and CYP2C19 and a moderate inhibitor of CYP2D6. Drugs that...

metabolized to norhydrocodone by cytochrome P450 3A4 and to hydromorphone, also biologically active, by cytochrome P450 2D6. For individuals who have a defect...

decarboxylase to give tryptamine, which is then hydroxylated by a cytochrome P450 monooxygenase, yielding serotonin. However, since serotonin is a major gastrointestinal...

group. The oxidation of the allyl side chain is mediated by a cytochrome P450 complex, which will transform safrole into 1′-hydroxysafrole. The newly formed...

cytochromes are involved in the mitochondrial electron transport chain. Cytochrome P450 enzymes perform the function of inserting an oxygen atom into a C−H bond...

humans, these include cytochrome P450 oxidases, UDP-glucuronosyltransferases, and glutathione S-transferases. This system of enzymes acts in three stages...

One notable system involved in metabolic drug interactions is the enzyme system comprising the cytochrome P450 oxidases. Cytochrome P450 is a very large...