• The pacemaker current (If, or IKf, also called funny current) is an electric current in the heart that flows through the HCN channel or pacemaker channel...
    10 KB (1,195 words) - 21:33, 8 November 2023
  • Thumbnail for Artificial cardiac pacemaker
    An artificial cardiac pacemaker, commonly referred to as simply a pacemaker, is an implanted medical device that generates electrical pulses delivered...
    80 KB (9,000 words) - 16:46, 21 June 2024
  • Thumbnail for Pacemaker potential
    cells of the heart (e.g., the sinoatrial node), the pacemaker potential (also called the pacemaker current) is the slow, positive increase in voltage across...
    7 KB (929 words) - 21:29, 2 September 2023
  • Thumbnail for Cardiac pacemaker
    are called pacemaker cells, and they directly control the heart rate. They make up the cardiac pacemaker, that is, the natural pacemaker of the heart...
    11 KB (1,469 words) - 18:44, 21 May 2024
  • The current through HCN channels, designated If or Ih, plays a key role in the control of cardiac and neuronal rhythmicity and is called the pacemaker current...
    14 KB (1,556 words) - 05:55, 3 June 2024
  • Thumbnail for Ivabradine
    the brand name Procoralan among others, is a medication, which is a pacemaker current (If) inhibitor, used for the symptomatic management of heart-related...
    24 KB (2,426 words) - 20:47, 7 June 2024
  • Thumbnail for Gerry and the Pacemakers
    Gerry and the Pacemakers were a British beat group prominent in the 1960s Merseybeat scene. In common with the Beatles, they came from Liverpool, were...
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  • Thumbnail for Sinoatrial node
    in the upper back wall of the right atrium made up of cells known as pacemaker cells. The sinus node is approximately 15 mm long, 3 mm wide, and 1 mm...
    24 KB (2,806 words) - 17:50, 24 April 2024
  • chronotropic effect. Beta blockers such as metoprolol Acetylcholine Digoxin Pacemaker current (i.e. HCN channel) inhibitors (e.g. ivabradine) Alboni, P.; Menozzi...
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  • Thumbnail for Interstitial cell of Cajal
    (1 July 1998). "Interstitial cells of Cajal generate a rhythmic pacemaker current". Nature Medicine. 4 (7): 848–851. doi:10.1038/nm0798-848. ISSN 1078-8956...
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  • and collaborators discovered the so-called "funny" (or "pacemaker") current in cardiac pacemaker cells, a new mechanism involved in the generation of cardiac...
    25 KB (2,620 words) - 10:56, 5 January 2024
  • A biological pacemaker is one or more types of cellular components that, when "implanted or injected into certain regions of the heart," produce specific...
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  • Thumbnail for Heart rate variability
    "pacemaker" current. The "Ik decay" hypothesis proposes that pacemaker depolarization results from slow deactivation of the delayed rectifier current,...
    70 KB (8,444 words) - 17:35, 28 June 2024
  • Thumbnail for Atropine
    potassium and calcium currents, as well as the slow-inward sodium current that is thought to be responsible for the pacemaker current (If). By hyperpolarizing...
    39 KB (3,656 words) - 02:17, 28 May 2024
  • Thumbnail for The Pacemaker
    The Pacemaker is a pocket-size DJ system invented by Jonas Norberg. The device features include a 120 GB hard drive, a signal-to-noise ratio of 103, and...
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  • organization Isiah Kiner-Falefa (born 1995), American baseball player Pacemaker current of the heart, IKf This disambiguation page lists articles associated...
    401 bytes (71 words) - 21:16, 31 May 2023
  • increasing the slope of the pacemaker phase, while parasympathetic activation exerts the opposite action. The amount of net inward current required to move the...
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  • activity (ECA) is the spontaneous depolarization and repolarization of pacemaker cells known as interstitial cells of Cajal (ICCs) in the smooth muscle...
    9 KB (1,111 words) - 22:08, 5 July 2022
  • later time. This contrasts with pacemaker potential or current which drives rhythmic modulation of firing rate. Some pacemaker action generate rhythms for...
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  • Thumbnail for Cardiac action potential
    known as pacemaker cells, that have automatic action potential generation capability. In healthy hearts, these cells form the cardiac pacemaker and are...
    46 KB (5,430 words) - 18:10, 24 April 2024
  • "Implantable pacemaker for the heart". In Smyth CN (ed.). Medical electronics. Paris: Iliffe & Sons. Warren J., Nelson J. (2000). "Pacemakers and ICD pulse...
    38 KB (4,547 words) - 02:37, 2 June 2024
  • limited its current load to under 0.1 mA and was thus considered useless. Greatbatch sought to introduce this invention into the pacemaker industry, which...
    11 KB (1,027 words) - 17:39, 8 June 2024
  • Pacemaker crosstalk results when the pacemaker-generated electrical event in one heart chamber is sensed by the lead in another chamber, resulting in inappropriate...
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  • must operate unattended for long periods of time, such as spacecraft, pacemakers, underwater systems and automated scientific stations in remote parts...
    25 KB (2,727 words) - 00:41, 24 May 2024
  • Thumbnail for Implantable cardioverter-defibrillator
    implantation of an ICD system is similar to implantation of a artificial pacemaker. In fact, ICDs are composed of an ICD generator and of wires. The first...
    33 KB (3,939 words) - 07:07, 25 June 2024
  • Thumbnail for Diaphragm pacing
    device to the commercial market in the early 1970s. The Avery Breathing Pacemaker received pre-market approval from the FDA in 1987 for "chronic ventilatory...
    22 KB (2,362 words) - 02:40, 19 March 2024
  • of a pacemaker has been advocated in a subset of individuals, in order to cause asynchronous contraction of the left ventricle. Since the pacemaker activates...
    82 KB (8,827 words) - 02:04, 19 June 2024
  • Thumbnail for Alinidine
    developed in the 1970s and 1980s. It causes bradycardia by inhibiting the pacemaker current by altering the maximal channel conductance and alter the voltage...
    3 KB (178 words) - 21:30, 28 August 2023
  • Thumbnail for Erotic electrostimulation
    cardiac arrest), and this risk is higher for those who use an artificial pacemaker or similar device or who have heart conditions. Because of this, it is...
    17 KB (2,017 words) - 14:26, 21 October 2023
  • The National Pacemaker Awards are awards for excellence in American student journalism, given annually since 1927. The awards are generally considered...
    46 KB (4,212 words) - 08:39, 16 April 2024